MARC1

Functionⁱ

As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively.1 Publication

Cofactorⁱ

Mo-molybdopterin2 PublicationsNote: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.2 Publications

Keywordsⁱ

Molecular function	Oxidoreductase
Ligand	Molybdenum

Enzyme and pathway databases

Reactomeⁱ	R-HSA-211945 Phase I - Functionalization of compounds

Reactomeⁱ

R-HSA-211945 Phase I - Functionalization of compounds

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Mitochondrial amidoxime-reducing component 1 (EC:1.-.-.-) Short name: mARC1 Alternative name(s): Molybdenum cofactor sulfurase C-terminal domain-containing protein 1 Short name: MOSC domain-containing protein 1 Short name: Moco sulfurase C-terminal domain-containing protein 1
Gene namesⁱ	Name:MARC1 Synonyms:MOSC1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000186205.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:26189 MARC1
MIMⁱ	614126 gene
neXtProtⁱ	NX_Q5VT66

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	2 – 20	Mitochondrial matrix1 PublicationAdd BLAST	19
Transmembraneⁱ	21 – 40	Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST	20
Topological domainⁱ	41 – 337	Cytoplasmic1 PublicationAdd BLAST	297

Keywords - Cellular componentⁱ

Membrane, Mitochondrion, Mitochondrion outer membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	64757
Open Targets More...OpenTargetsⁱ	ENSG00000186205
PharmGKBⁱ	PA142671344

Chemistry databases

ChEMBLⁱ	CHEMBL3706559

ChEMBLⁱ

CHEMBL3706559

Polymorphism and mutation databases

BioMutaⁱ	MARC1
DMDMⁱ	74746896

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		Removed2 Publications
ChainⁱPRO_0000273335	2 – 337	Mitochondrial amidoxime-reducing component 1Add BLAST		336

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Lipidationⁱ	2	N-myristoyl glycine2 Publications		1

Keywords - PTMⁱ

Lipoprotein, Myristate

Proteomic databases

EPDⁱ	Q5VT66
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q5VT66
PaxDbⁱ	Q5VT66
PeptideAtlas More...PeptideAtlasⁱ	Q5VT66
PRIDEⁱ	Q5VT66
ProteomicsDBⁱ	65307 65308 [Q5VT66-2] 65309 [Q5VT66-3]

PTM databases

iPTMnetⁱ	Q5VT66
PhosphoSitePlusⁱ	Q5VT66
SwissPalmⁱ	Q5VT66

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000186205 Expressed in 185 organ(s), highest expression level in adipose tissue
CleanExⁱ	HS_MOSC1
ExpressionAtlasⁱ	Q5VT66 baseline and differential
Genevisibleⁱ	Q5VT66 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA028702

HPAⁱ

HPA028702

Interactionⁱ

Subunit structureⁱ

Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase and MARC1.

Protein-protein interaction databases

BioGridⁱ	122271, 31 interactors
IntActⁱ	Q5VT66, 3 interactors
STRINGⁱ	9606.ENSP00000355877

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5VT66
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	187 – 335	MOSCPROSITE-ProRule annotationAdd BLAST		149

Keywords - Domainⁱ

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG2362 Eukaryota COG3217 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063150
HOVERGENⁱ	HBG081982
InParanoidⁱ	Q5VT66
OMAⁱ	CDPSERK
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0S9F
PhylomeDBⁱ	Q5VT66
TreeFamⁱ	TF316807

Family and domain databases

InterProⁱ	View protein in InterPro IPR005302 MoCF_Sase_C IPR005303 MOSC_N IPR011037 Pyrv_Knase-like_insert_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03473 MOSC, 1 hit PF03476 MOSC_N, 1 hit
SUPFAMⁱ	SSF50800 SSF50800, 2 hits
PROSITEⁱ	View protein in PROSITE PS51340 MOSC, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q5VT66-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGAAGSSALA RFVLLAQSRP GWLGVAALGL TAVALGAVAW RRAWPTRRRR 
        60         70         80         90        100
LLQQVGTVAQ LWIYPVKSCK GVPVSEAECT AMGLRSGNLR DRFWLVINQE 
       110        120        130        140        150
GNMVTARQEP RLVLISLTCD GDTLTLSAAY TKDLLLPIKT PTTNAVHKCR 
       160        170        180        190        200
VHGLEIEGRD CGEATAQWIT SFLKSQPYRL VHFEPHMRPR RPHQIADLFR 
       210        220        230        240        250
PKDQIAYSDT SPFLILSEAS LADLNSRLEK KVKATNFRPN IVISGCDVYA 
       260        270        280        290        300
EDSWDELLIG DVELKRVMAC SRCILTTVDP DTGVMSRKEP LETLKSYRQC 
       310        320        330 
DPSERKLYGK SPLFGQYFVL ENPGTIKVGD PVYLLGQ

Length:337

Mass (Da):37,499

Last modified:December 7, 2004 - v1

Checksum:ⁱF983AB08F3D646C4

GO

Isoform 2 (identifier: Q5VT66-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
251-251: E → EVTLCPFGSFLGFDFFFK

« Hide

        10         20         30         40         50
MGAAGSSALA RFVLLAQSRP GWLGVAALGL TAVALGAVAW RRAWPTRRRR 
        60         70         80         90        100
LLQQVGTVAQ LWIYPVKSCK GVPVSEAECT AMGLRSGNLR DRFWLVINQE 
       110        120        130        140        150
GNMVTARQEP RLVLISLTCD GDTLTLSAAY TKDLLLPIKT PTTNAVHKCR 
       160        170        180        190        200
VHGLEIEGRD CGEATAQWIT SFLKSQPYRL VHFEPHMRPR RPHQIADLFR 
       210        220        230        240        250
PKDQIAYSDT SPFLILSEAS LADLNSRLEK KVKATNFRPN IVISGCDVYA 
       260        270        280        290        300
EVTLCPFGSF LGFDFFFKDS WDELLIGDVE LKRVMACSRC ILTTVDPDTG 
       310        320        330        340        350
VMSRKEPLET LKSYRQCDPS ERKLYGKSPL FGQYFVLENP GTIKVGDPVY 

LLGQ

Note: No experimental confirmation available.

Show »

Length:354

Mass (Da):39,454

Checksum:ⁱCC368AD4B543AD51

GO

Isoform 3 (identifier: Q5VT66-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-102: Missing.
251-251: E → EVTLCPFGSFLGFDFFFK

« Hide

        10         20         30         40         50
MVTARQEPRL VLISLTCDGD TLTLSAAYTK DLLLPIKTPT TNAVHKCRVH 
        60         70         80         90        100
GLEIEGRDCG EATAQWITSF LKSQPYRLVH FEPHMRPRRP HQIADLFRPK 
       110        120        130        140        150
DQIAYSDTSP FLILSEASLA DLNSRLEKKV KATNFRPNIV ISGCDVYAEV 
       160        170        180        190        200
TLCPFGSFLG FDFFFKDSWD ELLIGDVELK RVMACSRCIL TTVDPDTGVM 
       210        220        230        240        250
SRKEPLETLK SYRQCDPSER KLYGKSPLFG QYFVLENPGT IKVGDPVYLL 

GQ

Note: No experimental confirmation available.

Show »

Length:252

Mass (Da):28,439

Checksum:ⁱ0FEF88317AF6C9D2

GO

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

H7BYZ9	H7BYZ9_HUMAN	Mitochondrial amidoxime-reducing co... Mitochondrial amidoxime-reducing component 1	MARC1	263	Annotation score:
H0YDX4	H0YDX4_HUMAN	Mitochondrial amidoxime-reducing co... Mitochondrial amidoxime-reducing component 1	MARC1	99	Annotation score:
X6RIL1	X6RIL1_HUMAN	Mitochondrial amidoxime-reducing co... Mitochondrial amidoxime-reducing component 1	MARC1	119	Annotation score:

Sequence cautionⁱ

The sequence BAB15333 differs from that shown. Reason: Frameshift at position 139.Curated

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_062273	15	L → H1 PublicationCorresponds to variant dbSNP:rs72470572Ensembl.	1
Natural variantⁱVAR_056941	96	V → L Common polymorphism in Caucasian population; no effect on binding of the molybdenum cofactor; no significant effect on catalytic efficiency toward benzamidoxime; no significant effect on affinity for benzamidoxime. 2 PublicationsCorresponds to variant dbSNP:rs12023067Ensembl.	1
Natural variantⁱVAR_030129	165	T → A No effect on binding of the molybdenum cofactor; no significant effect on catalytic efficiency toward benzamidoxime; no significant effect on affinity for benzamidoxime. 5 PublicationsCorresponds to variant dbSNP:rs2642438Ensembl.	1
Natural variantⁱVAR_030130	187	M → K No effect on binding of the molybdenum cofactor; no significant effect on catalytic efficiency toward benzamidoxime; no significant effect on affinity for benzamidoxime. 2 PublicationsCorresponds to variant dbSNP:rs17850677Ensembl.	1
Natural variantⁱVAR_030131	246	C → S No effect on binding of the molybdenum cofactor; no significant effect on catalytic efficiency toward benzamidoxime; no significant effect on affinity for benzamidoxime. 2 PublicationsCorresponds to variant dbSNP:rs3738178Ensembl.	1
Natural variantⁱVAR_062274	247	D → H No effect on binding of the molybdenum cofactor; no significant effect on catalytic efficiency toward benzamidoxime; no significant effect on affinity for benzamidoxime. 2 PublicationsCorresponds to variant dbSNP:rs72470601Ensembl.	1
Natural variantⁱVAR_030132	268	M → I No effect on binding of the molybdenum cofactor; no significant effect on catalytic efficiency toward benzamidoxime; no significant effect on affinity for benzamidoxime. 1 PublicationCorresponds to variant dbSNP:rs2642419Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_022511	1 – 102	Missing in isoform 3. 1 PublicationAdd BLAST		102
Alternative sequenceⁱVSP_022512	251	E → EVTLCPFGSFLGFDFFFK in isoform 2 and isoform 3. 1 Publication		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK026043 mRNA Translation: BAB15333.1 Frameshift. AK094105 mRNA Translation: BAC04286.1 AK290812 mRNA Translation: BAF83501.1 EU563849 Genomic DNA Translation: ACB21046.1 AL445423 Genomic DNA No translation available. AL606726 Genomic DNA No translation available. CH471100 Genomic DNA Translation: EAW93291.1 BC010619 mRNA Translation: AAH10619.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS1526.1 [Q5VT66-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_073583.3, NM_022746.3 [Q5VT66-1] XP_011508202.1, XM_011509900.2 [Q5VT66-2] XP_011508206.1, XM_011509904.2 [Q5VT66-3]
UniGeneⁱ	Hs.497816

Genome annotation databases

Ensemblⁱ	ENST00000366910; ENSP00000355877; ENSG00000186205 [Q5VT66-1]
GeneIDⁱ	64757
KEGGⁱ	hsa:64757
UCSC genome browser More...UCSCⁱ	uc001hms.4 human [Q5VT66-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q5VT66	Isoform 2 of Mitochondrial amidoxime-reducing component 1		HUMAN		354	UniRef90_Q5VT66
Uncharacterized protein		PANPA		340
Mitochondrial amidoxime reducing component 1		SAIBB		339
MOSC domain-containing protein 1, mitochondrial		CALJA		338
MOSC domain-containing protein 1, mitochondrial		MACMU		337
+48

Protein	Similar proteins		Species	Score	Length	Source
Q5VT66	Mitochondrial amidoxime reducing component 2		MOUSE		338	UniRef50_Q5VT66
Mitochondrial amidoxime reducing component 2		RAT		338
Mitochondrial amidoxime reducing component 2		HUMAN		335
Mitochondrial amidoxime reducing component 2		MACFA		335
Mitochondrial amidoxime reducing component 2		BOVIN		336
+263

Cross-referencesⁱ

Web resourcesⁱ

NIEHS-SNPs

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK026043 mRNA Translation: BAB15333.1 Frameshift. AK094105 mRNA Translation: BAC04286.1 AK290812 mRNA Translation: BAF83501.1 EU563849 Genomic DNA Translation: ACB21046.1 AL445423 Genomic DNA No translation available. AL606726 Genomic DNA No translation available. CH471100 Genomic DNA Translation: EAW93291.1 BC010619 mRNA Translation: AAH10619.1
CCDSⁱ	CCDS1526.1 [Q5VT66-1]
RefSeqⁱ	NP_073583.3, NM_022746.3 [Q5VT66-1] XP_011508202.1, XM_011509900.2 [Q5VT66-2] XP_011508206.1, XM_011509904.2 [Q5VT66-3]
UniGeneⁱ	Hs.497816

3D structure databases

ProteinModelPortalⁱ	Q5VT66
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	122271, 31 interactors
IntActⁱ	Q5VT66, 3 interactors
STRINGⁱ	9606.ENSP00000355877

Chemistry databases

ChEMBLⁱ	CHEMBL3706559

ChEMBLⁱ

CHEMBL3706559

PTM databases

iPTMnetⁱ	Q5VT66
PhosphoSitePlusⁱ	Q5VT66
SwissPalmⁱ	Q5VT66

Polymorphism and mutation databases

BioMutaⁱ	MARC1
DMDMⁱ	74746896

Proteomic databases

EPDⁱ	Q5VT66
MaxQBⁱ	Q5VT66
PaxDbⁱ	Q5VT66
PeptideAtlasⁱ	Q5VT66
PRIDEⁱ	Q5VT66
ProteomicsDBⁱ	65307 65308 [Q5VT66-2] 65309 [Q5VT66-3]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000366910; ENSP00000355877; ENSG00000186205 [Q5VT66-1]
GeneIDⁱ	64757
KEGGⁱ	hsa:64757
UCSCⁱ	uc001hms.4 human [Q5VT66-1]

Organism-specific databases

CTDⁱ	64757
DisGeNETⁱ	64757
EuPathDBⁱ	HostDB:ENSG00000186205.12
GeneCardsⁱ	MARC1
H-InvDBⁱ	HIX0001608
HGNCⁱ	HGNC:26189 MARC1
HPAⁱ	HPA028702
MIMⁱ	614126 gene
neXtProtⁱ	NX_Q5VT66
OpenTargetsⁱ	ENSG00000186205
PharmGKBⁱ	PA142671344
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2362 Eukaryota COG3217 LUCA
GeneTreeⁱ	ENSGT00530000063150
HOVERGENⁱ	HBG081982
InParanoidⁱ	Q5VT66
OMAⁱ	CDPSERK
OrthoDBⁱ	EOG091G0S9F
PhylomeDBⁱ	Q5VT66
TreeFamⁱ	TF316807

Enzyme and pathway databases

Reactomeⁱ	R-HSA-211945 Phase I - Functionalization of compounds

Reactomeⁱ

R-HSA-211945 Phase I - Functionalization of compounds

Miscellaneous databases

GenomeRNAiⁱ	64757
Protein Ontology More...PROⁱ	PR:Q5VT66
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000186205 Expressed in 185 organ(s), highest expression level in adipose tissue
CleanExⁱ	HS_MOSC1
ExpressionAtlasⁱ	Q5VT66 baseline and differential
Genevisibleⁱ	Q5VT66 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR005302 MoCF_Sase_C IPR005303 MOSC_N IPR011037 Pyrv_Knase-like_insert_dom_sf
Pfamⁱ	View protein in Pfam PF03473 MOSC, 1 hit PF03476 MOSC_N, 1 hit
SUPFAMⁱ	SSF50800 SSF50800, 2 hits
PROSITEⁱ	View protein in PROSITE PS51340 MOSC, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MARC1_HUMAN
Accessionⁱ	Q5VT66Primary (citable) accession number: Q5VT66 Secondary accession number(s): A8K447 Q9H6C7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
	Last sequence update:	December 7, 2004
	Last modified:	September 12, 2018
	This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

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UniRef

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Supporting data

UniProtKB - Q5VT66 (MARC1_HUMAN)

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Mitochondrial amidoxime-reducing component 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Other locations

Mitochondrion

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

Kineticsⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ