UniProtKB - Q5VT06 (CE350_HUMAN)
Centrosome-associated protein 350
CEP350
Functioni
GO - Molecular functioni
- microtubule binding Source: InterPro
GO - Biological processi
- microtubule anchoring Source: InterPro
- non-motile cilium assembly Source: Ensembl
- protein localization to centrosome Source: Ensembl
Enzyme and pathway databases
PathwayCommonsi | Q5VT06 |
SIGNORi | Q5VT06 |
Names & Taxonomyi
Protein namesi | Recommended name: Centrosome-associated protein 350CuratedShort name: Cep350 Alternative name(s): Centrosome-associated protein of 350 kDa1 Publication |
Gene namesi | ORF Names:GM1331 Publication |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000135837.15 |
HGNCi | HGNC:24238, CEP350 |
MIMi | 617870, gene |
neXtProti | NX_Q5VT06 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Cytoskeleton
- centrosome 4 Publications
- spindle 1 Publication
- centriole 2 Publications
- cilium basal body 1 Publication
Note: Associated with mitotic spindles (PubMed:16314388). Nuclear, in discrete foci. Associated with intermediate filaments (PubMed:15615782). Also present in the pericentrosomal area (PubMed:17878239). Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole (PubMed:28625565). Localizes to the distal end of the centriole on the subdistal appendage region (PubMed:28659385).5 Publications
Cytoskeleton
- centriole Source: UniProtKB
- centrosome Source: UniProtKB
- spindle Source: UniProtKB-SubCell
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- cell projection Source: UniProtKB-KW
- cytoplasm Source: UniProtKB-KW
- membrane Source: UniProtKB
Keywords - Cellular componenti
Cell projection, Cytoplasm, Cytoskeleton, NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 762 – 763 | LL → AA: Abolishes recruitment of PPARA to specific nuclear foci. No effect on interaction with PPARA (in vitro). 1 Publication | 2 |
Organism-specific databases
DisGeNETi | 9857 |
OpenTargetsi | ENSG00000135837 |
PharmGKBi | PA143485434 |
Miscellaneous databases
Pharosi | Q5VT06, Tbio |
Polymorphism and mutation databases
BioMutai | CEP350 |
DMDMi | 74746869 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000233291 | 1 – 3117 | Centrosome-associated protein 350Add BLAST | 3117 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 86 | PhosphoserineCombined sources | 1 | |
Modified residuei | 139 | PhosphoserineCombined sources | 1 | |
Modified residuei | 142 | PhosphoserineCombined sources | 1 | |
Modified residuei | 218 | PhosphoserineCombined sources | 1 | |
Modified residuei | 473 | PhosphoserineCombined sources | 1 | |
Modified residuei | 507 | PhosphoserineCombined sources | 1 | |
Modified residuei | 695 | PhosphoserineCombined sources | 1 | |
Modified residuei | 878 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 939 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1061 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1253 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 1256 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1259 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1613 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1648 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1653 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1818 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1936 | PhosphoserineBy similarity | 1 | |
Modified residuei | 2115 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2204 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 2206 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2431 | PhosphoserineBy similarity | 1 | |
Modified residuei | 2460 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2689 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 2830 | PhosphoserineBy similarity | 1 | |
Modified residuei | 2839 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q5VT06 |
jPOSTi | Q5VT06 |
MassIVEi | Q5VT06 |
MaxQBi | Q5VT06 |
PaxDbi | Q5VT06 |
PeptideAtlasi | Q5VT06 |
PRIDEi | Q5VT06 |
ProteomicsDBi | 65290 |
PTM databases
iPTMneti | Q5VT06 |
PhosphoSitePlusi | Q5VT06 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000135837, Expressed in testis and 256 other tissues |
ExpressionAtlasi | Q5VT06, baseline and differential |
Genevisiblei | Q5VT06, HS |
Organism-specific databases
HPAi | ENSG00000135837, Low tissue specificity |
Interactioni
Subunit structurei
Part of a ternary complex that contains CEP350, CEP43 and MAPRE1.
Interacts (via C-terminus) directly with CEP43 (via N-terminus) (PubMed:16314388, PubMed:28625565, PubMed:28428259).
Interacts with NR1H3, PPARA, PPARD and PPARG (PubMed:15615782).
Interacts directly with microtubules (PubMed:17878239).
Interacts with the fusion protein CEP43-FGFR1, and by doing so recruits and activates PI3K and PLC-gamma (PubMed:18412956).
Interacts with CYLD (PubMed:25134987).
Interacts with CFAP157 (By similarity).
Interacts with CEP19 (via C-terminus) (PubMed:28659385).
By similarity8 PublicationsBinary interactionsi
Q5VT06
With | #Exp. | IntAct |
---|---|---|
CTNNA1 [P35221] | 5 | EBI-947346,EBI-701918 |
GO - Molecular functioni
- microtubule binding Source: InterPro
Protein-protein interaction databases
BioGRIDi | 115191, 76 interactors |
DIPi | DIP-49946N |
IntActi | Q5VT06, 69 interactors |
MINTi | Q5VT06 |
STRINGi | 9606.ENSP00000356579 |
Miscellaneous databases
RNActi | Q5VT06, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q5VT06 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q5VT06 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2517 – 2559 | CAP-GlyPROSITE-ProRule annotationAdd BLAST | 43 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 598 – 645 | Sequence analysisAdd BLAST | 48 | |
Coiled coili | 1369 – 1411 | Sequence analysisAdd BLAST | 43 | |
Coiled coili | 1707 – 1800 | Sequence analysisAdd BLAST | 94 | |
Coiled coili | 1856 – 1899 | Sequence analysisAdd BLAST | 44 | |
Coiled coili | 2051 – 2110 | Sequence analysisAdd BLAST | 60 | |
Coiled coili | 2719 – 2752 | Sequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1112 – 1281 | Ser-richAdd BLAST | 170 | |
Compositional biasi | 1502 – 1556 | Ser-richAdd BLAST | 55 |
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | KOG4568, Eukaryota |
GeneTreei | ENSGT00940000155130 |
HOGENOMi | CLU_000421_0_0_1 |
InParanoidi | Q5VT06 |
OMAi | ADITTSW |
PhylomeDBi | Q5VT06 |
TreeFami | TF329845 |
Family and domain databases
Gene3Di | 2.30.30.190, 1 hit |
InterProi | View protein in InterPro IPR036859, CAP-Gly_dom_sf IPR000938, CAP-Gly_domain IPR028750, CEP350 IPR025486, DUF4378 |
PANTHERi | PTHR13958, PTHR13958, 1 hit |
Pfami | View protein in Pfam PF01302, CAP_GLY, 1 hit PF14309, DUF4378, 1 hit |
SMARTi | View protein in SMART SM01052, CAP_GLY, 1 hit |
SUPFAMi | SSF74924, SSF74924, 1 hit |
PROSITEi | View protein in PROSITE PS00845, CAP_GLY_1, 1 hit PS50245, CAP_GLY_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MRSSKSKEVP LPNPRNSQSK DTVQADITTS WDALSQTKAA LRHIENKLEV
60 70 80 90 100
APTSTAVCDS VMDTKKSSTS ATRKISRKDG RYLDDSWVNA PISKSTKSRK
110 120 130 140 150
EKSRSPLRAT TLESNVKKNN RVEFREPLVS YREIHGAPSN FSSSHLESKH
160 170 180 190 200
VYCVDVNEEK TESGNWMIGS REERNIRSCD FESSQSSVIN DTVVRFLNDR
210 220 230 240 250
PAIDALQNSE CLIRMGASMR TEEEMPNRTK GSENNLKLSV NNMAHDTDPK
260 270 280 290 300
ALRLTDSSPS STSTSNSQRL DILKRRQHDV KLEKLKERIR KQWEHSEETN
310 320 330 340 350
GRGQKLGHID HPVMVVNVDN SVTAKVRKVA TAPPAPAYKG FNPSETKIRT
360 370 380 390 400
PDGKVWQEAE FQNMSRELYR DLALHFADDI SIKEKPAEKS KEKKVVKPVR
410 420 430 440 450
KVQKVAQLSS TECRTGSSHL ISTSSWRDGQ KLVKKILGPA PRMEPKEQRT
460 470 480 490 500
ASSDRGGRER TAKSGGHIGR AESDPRLDVL HRHLQRNSER SRSKSRSENN
510 520 530 540 550
IKKLASSLPD NKQEENTALN KDFLPIEIRG ILDDLQLDST AHTAKQDTVE
560 570 580 590 600
LQNQKSSAPV HAPRSHSPVK RKPDKITANE DPPVISKRRH YDTDEVRQYI
610 620 630 640 650
VRQQEERKRK QNEEKKAQKE ATEQKNKRLQ ELYRKQKEAF TKVKNVPPSE
660 670 680 690 700
PSATRRLQET YSKLLLEKTL LEEPSHQHVT QETQAKPGYQ PSGESDKENK
710 720 730 740 750
VQERPPSASS SSDMSLSEPP QPLARKDLME STWMQPERLS PQVHHSQPQP
760 770 780 790 800
FAGTAGSLLS HLLSLEHVGI LHKDFESILP TRKNHNMASR PLTFTPQPYV
810 820 830 840 850
TSPAAYTDAL LKPSASQYKS KLDRIEALKA TAASLSSRIE SEAKKLAGAS
860 870 880 890 900
INYGSAWNTE YDVQQAPQED GPWTKAVTPP VKDDNEDVFS ARIQKMLGSC
910 920 930 940 950
VSHATFDDDL PGVGNLSEFK KLPEMIRPQS AISSFRVRSP GPKPEGLLAQ
960 970 980 990 1000
LCKRQTDSSS SDMQACSQDK AKISLGSSID SVSEGPLLSE GSLSEEEGDQ
1010 1020 1030 1040 1050
DGQPLLKVAE ILKEKEFCPG ERNSYEPIKE FQKEAEKFLP LFGHIGGTQS
1060 1070 1080 1090 1100
KGPWEELAKG SPHSVINIFT KSYQLYGKGF EDKLDRGTST SRPLNATATP
1110 1120 1130 1140 1150
LSGVSYEDDF VSSPGTGTST EKKSTLEPHS TLSPQEDHSN RKSAYDPSSV
1160 1170 1180 1190 1200
DVTSQHSSGA QSAASSRSST SSKGKKGKKE KTEWLDSFTG NVQNSLLDEE
1210 1220 1230 1240 1250
KAERGSHQGK KSGTSSKLSV KDFEQTLDTD STLEDLSGHS VSVSSDKGRS
1260 1270 1280 1290 1300
QKTPTSPLSP SSQKSLQFDV AGTSSERSKS SVMPPTITGF KPNAPLTDLN
1310 1320 1330 1340 1350
PAASRTTTEN MAPIPGSKRF SPAGLHHRMA AELSYLNAIE ESVRQLSDVE
1360 1370 1380 1390 1400
RVRGISLAQQ ESVSLAQIIK AQQQRHERDL ALLKLKAEQE ALESQRQLEE
1410 1420 1430 1440 1450
TRNKAAQVHA ESLQQVVQSQ REVTEVLQEA TCKIAAQQSE TARLTTDAAR
1460 1470 1480 1490 1500
QICEMAELTR THISDAVVAS GAPLAILYDH QRQHLPDFVK QLRTRTETDR
1510 1520 1530 1540 1550
KSPSVSLSQS KEGTLDSKHQ KYSASYDSYS ESSGYKNHDR RSSSGSSRQE
1560 1570 1580 1590 1600
SPSVPSCKEN EKKLNGEKIE SSIDEQVQTA ADDSLRSDSV PSLPDEKDST
1610 1620 1630 1640 1650
SIATEYSLKF DESMTEDEIE EQSFRSLLPS ESHRRFNMEK RRGHHDDSDE
1660 1670 1680 1690 1700
EASPEKTTLS TAKELNMPFS GGQDSFSKFT MEMVRQYMKE EEMRAAHQSS
1710 1720 1730 1740 1750
LLRLREKALK EKTKAELAWL EHQKKHLRDK GEDDKMPPLR KKQRGLLLRL
1760 1770 1780 1790 1800
QQEKAEIKRL QEANKAARKE RQLILKQQEE IEKIRQTTIK LQEKLKSAGE
1810 1820 1830 1840 1850
SKLDSHSDDD TKDNKATSPG PTDLETRSPS PISISSSETS SIMQKLKKMR
1860 1870 1880 1890 1900
SRMDEKFLTK REQKLMQRRQ HAEELLEWKR RLDAEEAEIR QMEKQALAAW
1910 1920 1930 1940 1950
DKELIKPKTP KKELEDQRTE QKEIASEEES PVPLYSHLNS ESSIPEELGS
1960 1970 1980 1990 2000
PAVEYVPSES IGQEQPGSPD HSILTEEMIC SQELESSTSP SKHSLPKSCT
2010 2020 2030 2040 2050
SVSKQESSKG SHRTGGQCHL PIKSHQHCYS WSDESLSMTQ SETTSDQSDI
2060 2070 2080 2090 2100
EGRIRALKDE LRKRKSVVNQ LKKEQKKRQK ERLKAQEASL IKQLESYDEF
2110 2120 2130 2140 2150
IKKTEAELSQ DLETSPTAKP QIKTLSSASE KPKIKPLTPL HRSETAKNWK
2160 2170 2180 2190 2200
SLTESERSRG SLESIAEHVD ASLSGSERSV SERSLSAYAK RVNEWDSRTE
2210 2220 2230 2240 2250
DFQTPSPVLR SSRKIREESG DSLENVPALH LLKELNATSR ILDMSDGKVG
2260 2270 2280 2290 2300
ESSKKSEIKE IEYTKLKKSK IEDAFSKEGK SDVLLKLVLE QGDSSEILSK
2310 2320 2330 2340 2350
KDLPLDSENV QKDLVGLAIE NLHKSEEMLK ERQSDQDMNH SPNIQSGKDI
2360 2370 2380 2390 2400
HEQKNTKEKD LSWSEHLFAP KEIPYSEDFE VSSFKKEISA ELYKDDFEVS
2410 2420 2430 2440 2450
SLLSLRKDSQ SCRDKPQPMR SSTSGATSFG SNEEISECLS EKSLSIHSNV
2460 2470 2480 2490 2500
HSDRLLELKS PTELMKSKER SDVEHEQQVT ESPSLASVPT ADELFDFHIG
2510 2520 2530 2540 2550
DRVLIGNVQP GILRFKGETS FAKGFWAGVE LDKPEGNNNG TYDGIAYFEC
2560 2570 2580 2590 2600
KEKHGIFAPP QKISHIPENF DDYVDINEDE DCYSDERYQC YNQEQNDTEG
2610 2620 2630 2640 2650
PKDREKDVSE YFYEKSLPSV NDIEASVNRS RSLKIETDNV QDISGVLEAH
2660 2670 2680 2690 2700
VHQQSSVDSQ ISSKENKDLI SDATEKVSIA AEDDTLDNTF SEELEKQQQF
2710 2720 2730 2740 2750
TEEEDNLYAE ASEKLCTPLL DLLTREKNQL EAQLKSSLNE EKKSKQQLEK
2760 2770 2780 2790 2800
ISLLTDSLLK VFVKDTVNQL QQIKKTRDEK IQLSNQELLG DDQKKVTPQD
2810 2820 2830 2840 2850
LSQNVEEQSP SISGCFLSSE LEDEKEEISS PDMCPRPESP VFGASGQEEL
2860 2870 2880 2890 2900
AKRLAELELS REFLSALGDD QDWFDEDFGL SSSHKIQKNK AEETIVPLMA
2910 2920 2930 2940 2950
EPKRVTQQPC ETLLAVPHTA EEVEILVHNA AEELWKWKEL GHDLHSISIP
2960 2970 2980 2990 3000
TKLLGCASKG LDIESTSKRV YKQAVFDLTK EIFEEIFAED PNLNQPVWMK
3010 3020 3030 3040 3050
PCRINSSYFR RVKNPNNLDE IKSFIASEVL KLFSLKKEPN HKTDWQKMMK
3060 3070 3080 3090 3100
FGRKKRDRVD HILVQELHEE EAQWVNYDED ELCVKMQLAD GIFETLIKDT
3110
IDVLNQISEK QGRMLLV
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0Y7F7 | H0Y7F7_HUMAN | Centrosome-associated protein 350 | CEP350 | 1,292 | Annotation score: | ||
H0Y6Q4 | H0Y6Q4_HUMAN | Centrosome-associated protein 350 | CEP350 | 331 | Annotation score: | ||
E9PIK0 | E9PIK0_HUMAN | Centrosome-associated protein 350 | CEP350 | 242 | Annotation score: | ||
Q5T2X5 | Q5T2X5_HUMAN | Centrosome-associated protein 350 | CEP350 | 110 | Annotation score: | ||
Q5T2X4 | Q5T2X4_HUMAN | Centrosome-associated protein 350 | CEP350 | 581 | Annotation score: | ||
A2A4F6 | A2A4F6_HUMAN | Centrosome-associated protein 350 | CEP350 | 130 | Annotation score: | ||
H0YD38 | H0YD38_HUMAN | Centrosome-associated protein 350 | CEP350 | 57 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 25 | Missing in AAL91355 (PubMed:11891061).Curated | 1 | |
Sequence conflicti | 114 | S → G in AAL55733 (Ref. 1) Curated | 1 | |
Sequence conflicti | 459 | E → R in AAL55733 (Ref. 1) Curated | 1 | |
Sequence conflicti | 2164 | S → P in AAL55733 (Ref. 1) Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_059202 | 892 | R → T. Corresponds to variant dbSNP:rs6692219Ensembl. | 1 | |
Natural variantiVAR_026126 | 945 | E → Q1 PublicationCorresponds to variant dbSNP:rs2477120Ensembl. | 1 | |
Natural variantiVAR_059203 | 1213 | G → V. Corresponds to variant dbSNP:rs12125245Ensembl. | 1 | |
Natural variantiVAR_048671 | 1445 | T → A. Corresponds to variant dbSNP:rs16855164Ensembl. | 1 | |
Natural variantiVAR_059204 | 1446 | T → A. Corresponds to variant dbSNP:rs16855164Ensembl. | 1 | |
Natural variantiVAR_059205 | 1517 | S → A. Corresponds to variant dbSNP:rs12124336Ensembl. | 1 | |
Natural variantiVAR_061092 | 2044 | T → P. Corresponds to variant dbSNP:rs56173179Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF287356 mRNA Translation: AAL55733.1 AL645487 Genomic DNA No translation available. AL590632 Genomic DNA No translation available. AL390718 Genomic DNA No translation available. AF387614 mRNA Translation: AAL91355.1 |
CCDSi | CCDS1336.1 |
PIRi | T00263 |
RefSeqi | NP_055625.4, NM_014810.4 |
Genome annotation databases
Ensembli | ENST00000367607; ENSP00000356579; ENSG00000135837 |
GeneIDi | 9857 |
KEGGi | hsa:9857 |
UCSCi | uc001gnt.4, human |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF287356 mRNA Translation: AAL55733.1 AL645487 Genomic DNA No translation available. AL590632 Genomic DNA No translation available. AL390718 Genomic DNA No translation available. AF387614 mRNA Translation: AAL91355.1 |
CCDSi | CCDS1336.1 |
PIRi | T00263 |
RefSeqi | NP_055625.4, NM_014810.4 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2COZ | NMR | - | A | 2473-2581 | [»] | |
SMRi | Q5VT06 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 115191, 76 interactors |
DIPi | DIP-49946N |
IntActi | Q5VT06, 69 interactors |
MINTi | Q5VT06 |
STRINGi | 9606.ENSP00000356579 |
PTM databases
iPTMneti | Q5VT06 |
PhosphoSitePlusi | Q5VT06 |
Polymorphism and mutation databases
BioMutai | CEP350 |
DMDMi | 74746869 |
Proteomic databases
EPDi | Q5VT06 |
jPOSTi | Q5VT06 |
MassIVEi | Q5VT06 |
MaxQBi | Q5VT06 |
PaxDbi | Q5VT06 |
PeptideAtlasi | Q5VT06 |
PRIDEi | Q5VT06 |
ProteomicsDBi | 65290 |
Protocols and materials databases
Antibodypediai | 34424, 68 antibodies |
Genome annotation databases
Ensembli | ENST00000367607; ENSP00000356579; ENSG00000135837 |
GeneIDi | 9857 |
KEGGi | hsa:9857 |
UCSCi | uc001gnt.4, human |
Organism-specific databases
CTDi | 9857 |
DisGeNETi | 9857 |
EuPathDBi | HostDB:ENSG00000135837.15 |
GeneCardsi | CEP350 |
HGNCi | HGNC:24238, CEP350 |
HPAi | ENSG00000135837, Low tissue specificity |
MIMi | 617870, gene |
neXtProti | NX_Q5VT06 |
OpenTargetsi | ENSG00000135837 |
PharmGKBi | PA143485434 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4568, Eukaryota |
GeneTreei | ENSGT00940000155130 |
HOGENOMi | CLU_000421_0_0_1 |
InParanoidi | Q5VT06 |
OMAi | ADITTSW |
PhylomeDBi | Q5VT06 |
TreeFami | TF329845 |
Enzyme and pathway databases
PathwayCommonsi | Q5VT06 |
SIGNORi | Q5VT06 |
Miscellaneous databases
BioGRID-ORCSi | 9857, 62 hits in 849 CRISPR screens |
ChiTaRSi | CEP350, human |
EvolutionaryTracei | Q5VT06 |
GeneWikii | CEP350 |
GenomeRNAii | 9857 |
Pharosi | Q5VT06, Tbio |
PROi | PR:Q5VT06 |
RNActi | Q5VT06, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000135837, Expressed in testis and 256 other tissues |
ExpressionAtlasi | Q5VT06, baseline and differential |
Genevisiblei | Q5VT06, HS |
Family and domain databases
Gene3Di | 2.30.30.190, 1 hit |
InterProi | View protein in InterPro IPR036859, CAP-Gly_dom_sf IPR000938, CAP-Gly_domain IPR028750, CEP350 IPR025486, DUF4378 |
PANTHERi | PTHR13958, PTHR13958, 1 hit |
Pfami | View protein in Pfam PF01302, CAP_GLY, 1 hit PF14309, DUF4378, 1 hit |
SMARTi | View protein in SMART SM01052, CAP_GLY, 1 hit |
SUPFAMi | SSF74924, SSF74924, 1 hit |
PROSITEi | View protein in PROSITE PS00845, CAP_GLY_1, 1 hit PS50245, CAP_GLY_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CE350_HUMAN | |
Accessioni | Q5VT06Primary (citable) accession number: Q5VT06 Secondary accession number(s): O75068, Q8TDK3, Q8WY20 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 2, 2006 |
Last sequence update: | December 7, 2004 | |
Last modified: | December 2, 2020 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations