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Protein

Putative serine/threonine-protein kinase/receptor R818

Gene

MIMI_R818

Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei820ATPPROSITE-ProRule annotation1
Active sitei915Proton acceptorBy similarity1
Binding sitei1421ATPPROSITE-ProRule annotation1
Active sitei1515Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi799 – 807ATPPROSITE-ProRule annotation9
Nucleotide bindingi1400 – 1408ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Receptor, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein kinase/receptor R818 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:MIMI_R818
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
Proteomesi
  • UP000001134 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei749 – 769HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000025399620 – 1651Putative serine/threonine-protein kinase/receptor R818Add BLAST1632

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi111N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi135N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi190N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi236N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi275N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi276N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi287N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi452N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi455N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi477N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi495N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi540N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi596N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi722N-linked (GlcNAc...) asparagine; by hostSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ5UQG7

Structurei

3D structure databases

ProteinModelPortaliQ5UQG7
SMRiQ5UQG7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini793 – 1057Protein kinase 1PROSITE-ProRule annotationAdd BLAST265
Domaini1135 – 1278Guanylate cyclasePROSITE-ProRule annotationAdd BLAST144
Domaini1394 – 1645Protein kinase 2PROSITE-ProRule annotationAdd BLAST252

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1110 – 1113Poly-Ser4

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di3.30.70.1230, 1 hit
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR011009 Kinase-like_dom_sf
IPR029787 Nucleotide_cyclase
IPR024370 PBP_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 1 hit
PF12849 PBP_like_2, 2 hits
PF07714 Pkinase_Tyr, 2 hits
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00044 CYCc, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF55073 SSF55073, 1 hit
SSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS50125 GUANYLATE_CYCLASE_2, 1 hit
PS00107 PROTEIN_KINASE_ATP, 2 hits
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5UQG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSIGIFVVA LWLTHFCDGG QLGARIYSSG SESSVLLFDQ YINKYAFTNG
60 70 80 90 100
DVKIIYEGKS IFEILSETYV TDFNIFDRAI SQDNLDMFQI VQFPLAGQAI
110 120 130 140 150
VMTYNLPELV NSSYRLVIDR ETLGKIWYGA ISKWNDTAIQ NLNPTVGHLL
160 170 180 190 200
PDTDIILGYS DDYIMTISGL IKMALSSFSP EFDTELKYAN NTFNGMNPTK
210 220 230 240 250
NGRGHNIGET STVRLEWLKK TSYGLTYINY ADVYNNGTDS TVPMNMYNKA
260 270 280 290 300
GYFVEPNLVS VQAAMSDFKI FYANNNSTID IYDAPGNKSW PLAYVNYLGC
310 320 330 340 350
SSAFGPMADC TRTIQMTNFI AWIYTNDAAS ESAIELQFYP LDKTLQKVAI
360 370 380 390 400
DNLYNIKCNN IAVLSQQYLI GFGAPISVMS LWPNSWTTVA STARYYSAPS
410 420 430 440 450
SQALELQETY GADFGITVTG VPNTYFNKMP DLGVMPLAAF TIVPAYNIPA
460 470 480 490 500
INGTNGTLIL DYEIITDIYL GIINNWNDSR IRALNGIEIN RKLPNVSITV
510 520 530 540 550
IYQAVSSDYN FMFTDFMSKK SPKFAKKIGS TYFPILTLPN NSMIITTDIY
560 570 580 590 600
DVGNQLISNS NSFAFWPYFG ITMLSRQPTV QAASIRTEKG NIISSNSTTL
610 620 630 640 650
EKAINNFISK GGSIEDAPYI MGENDESWPL SALMTMIYRQ STIHYAAKAA
660 670 680 690 700
AVADFAYWTQ SNPTAINIAT IQGMYVASNN PTLKSRNLNL LKNFVVDGEP
710 720 730 740 750
ISSIANCIYQ GTICSDMGTC NNNSCLCNSY RKGIYCENIV SSSGESIGII
760 770 780 790 800
LAIVIPVSFV ICCIIIVLVI ALIVSIRLHQ RVEDEWEVDF HELDFMESLG
810 820 830 840 850
SGGSGEVFKA MWKGTEVAVK KLVNSNITKD AERNFKQEIH RMTSLRHPNV
860 870 880 890 900
VLFMAASTRP PNMCIVMEFM SLGSLYDLLG NELVTEIPPV LRIRIAYQAA
910 920 930 940 950
KGMHFLHSSD IVHRDLKSLN LLLDSKWNVK VSDFGLTKIK DNNKGKSSTK
960 970 980 990 1000
EDSVCSIQWT APEVLSEKQD IDYILADVYS FGIIMWELMT RLRPYIGLSP
1010 1020 1030 1040 1050
AAIAVAVIRD NLRPEIQEED INLMSSDYVE LVNICWHKDT MIRPSFLEIM
1060 1070 1080 1090 1100
TKLSTLIGGS GITTGTSTSS SNQSSDYIGP NIITRTKNIH NNDETKNSFG
1110 1120 1130 1140 1150
STTYGSNTIS SSSNTESDKI LSKLNKKKIP TGEVIIVFTD IISAEQLWHH
1160 1170 1180 1190 1200
NPLAMKNATV LYNAVIRETL DKIGGYESFI YKDHNSGEGS FCLVFQEAID
1210 1220 1230 1240 1250
AIDFCSISQK KLLEIDWPEE LLDHPAAASE KDINGTMIFA GPRVRMGLHA
1260 1270 1280 1290 1300
GTVKIMQDPV TRRYEYSGVT VNIAAKITMM THGGQVIMSE QVTDKISNND
1310 1320 1330 1340 1350
CSNIKSLGQI EITDTNNYKV NIFELRIEGL IGRFFGGVAF YNYDSVTEST
1360 1370 1380 1390 1400
DLDDTYPDSL NFSTNGILYG GIKQENEYLS SAGLCRWIIN YDDIQIGKQI
1410 1420 1430 1440 1450
GVGSYGIVNM GKWKNINVAV KKFVKQKIDE KQMLEFRAEI AFLSQLRHPH
1460 1470 1480 1490 1500
IILMIGACLK RPNICIVTEF MGNGSLRNVI KTTKPEWKLK IKMLYQTALG
1510 1520 1530 1540 1550
IGYLHNSDPI IIHRDIKPSN ILVDDSMNVK IADFGFARIK EENSVMTRCG
1560 1570 1580 1590 1600
TPCWTAPEII RGEKYTEKVD VFSFGIVMWE VLTCKEPFSG CNFMKVSMDI
1610 1620 1630 1640 1650
LEGARPQIPS DCPIDFTKLM KQCWHAKPDK RPSMEDVIMG LNDMLGPEKS

L
Length:1,651
Mass (Da):184,362
Last modified:December 7, 2004 - v1
Checksum:iACD50969F68DA309
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY653733 Genomic DNA Translation: AAV51078.1
RefSeqiYP_003987350.1, NC_014649.1

Genome annotation databases

GeneIDi9925481
KEGGivg:9925481

Similar proteinsi

Entry informationi

Entry nameiYR818_MIMIV
AccessioniPrimary (citable) accession number: Q5UQG7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: December 7, 2004
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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