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Protein

Uncharacterized protein C12orf60

Gene

C12orf60

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C12orf60
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000182993.3
HGNCiHGNC:28726 C12orf60
neXtProtiNX_Q5U649

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182993
PharmGKBiPA143485389

Polymorphism and mutation databases

BioMutaiC12orf60
DMDMi125863778

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002742711 – 245Uncharacterized protein C12orf60Add BLAST245

Proteomic databases

EPDiQ5U649
PaxDbiQ5U649
PeptideAtlasiQ5U649
PRIDEiQ5U649
ProteomicsDBi65239

PTM databases

iPTMnetiQ5U649
PhosphoSitePlusiQ5U649

Expressioni

Gene expression databases

BgeeiENSG00000182993 Expressed in 149 organ(s), highest expression level in testis
CleanExiHS_C12orf60
GenevisibleiQ5U649 HS

Organism-specific databases

HPAiHPA043911

Interactioni

Protein-protein interaction databases

IntActiQ5U649, 1 interactor
STRINGi9606.ENSP00000331691

Structurei

3D structure databases

ProteinModelPortaliQ5U649
SMRiQ5U649
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IFFE Eukaryota
ENOG4111DAN LUCA
GeneTreeiENSGT00390000003800
HOGENOMiHOG000111765
HOVERGENiHBG081242
InParanoidiQ5U649
OMAiPIMNLQL
OrthoDBiEOG091G0M4L
PhylomeDBiQ5U649
TreeFamiTF338464

Family and domain databases

InterProiView protein in InterPro
IPR027895 DUF4533
PfamiView protein in Pfam
PF15047 DUF4533, 1 hit

Sequencei

Sequence statusi: Complete.

Q5U649-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSESEKDKE RLIQAAKMFF FHVQDLASVI NTLTELFSRS MNTQILLMAV
60 70 80 90 100
KNNSYIKDFF EQMLKIFKEM QSVVDARHDK IQKESLCSKV AMAMCSVVQK
110 120 130 140 150
STNVEELHQS AKEVFKSAHT PVIISVLNSS NILGSLESSL SHLMKFPIMN
160 170 180 190 200
LQLSDFYTED TKEQSDVTTS ERTRSPPGSS KTTMIDTLKK LQDVLKTEDS
210 220 230 240
KNPTKSAADL LEQIVKAMGP ILEILQKAIK TMEMNISVFK KASDK
Length:245
Mass (Da):27,626
Last modified:February 6, 2007 - v2
Checksum:iC424D710741D7FD5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti42N → D in AAH29443 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03022651K → R1 PublicationCorresponds to variant dbSNP:rs17853860Ensembl.1
Natural variantiVAR_03022765K → R. Corresponds to variant dbSNP:rs7304054Ensembl.1
Natural variantiVAR_030228103N → K. Corresponds to variant dbSNP:rs7307438Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289942 mRNA Translation: BAF82631.1
BC015546 mRNA Translation: AAH15546.1
BC029443 mRNA Translation: AAH29443.1
BC038836 mRNA Translation: AAH38836.1
CCDSiCCDS8667.1
RefSeqiNP_787070.2, NM_175874.3
XP_005253379.1, XM_005253322.4
XP_011518870.1, XM_011520568.2
XP_011518871.1, XM_011520569.2
XP_016874360.1, XM_017018871.1
XP_016874361.1, XM_017018872.1
XP_016874362.1, XM_017018873.1
XP_016874363.1, XM_017018874.1
UniGeneiHs.659951

Genome annotation databases

EnsembliENST00000330828; ENSP00000331691; ENSG00000182993
GeneIDi144608
KEGGihsa:144608
UCSCiuc001rcj.5 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289942 mRNA Translation: BAF82631.1
BC015546 mRNA Translation: AAH15546.1
BC029443 mRNA Translation: AAH29443.1
BC038836 mRNA Translation: AAH38836.1
CCDSiCCDS8667.1
RefSeqiNP_787070.2, NM_175874.3
XP_005253379.1, XM_005253322.4
XP_011518870.1, XM_011520568.2
XP_011518871.1, XM_011520569.2
XP_016874360.1, XM_017018871.1
XP_016874361.1, XM_017018872.1
XP_016874362.1, XM_017018873.1
XP_016874363.1, XM_017018874.1
UniGeneiHs.659951

3D structure databases

ProteinModelPortaliQ5U649
SMRiQ5U649
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5U649, 1 interactor
STRINGi9606.ENSP00000331691

PTM databases

iPTMnetiQ5U649
PhosphoSitePlusiQ5U649

Polymorphism and mutation databases

BioMutaiC12orf60
DMDMi125863778

Proteomic databases

EPDiQ5U649
PaxDbiQ5U649
PeptideAtlasiQ5U649
PRIDEiQ5U649
ProteomicsDBi65239

Protocols and materials databases

DNASUi144608
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000330828; ENSP00000331691; ENSG00000182993
GeneIDi144608
KEGGihsa:144608
UCSCiuc001rcj.5 human

Organism-specific databases

CTDi144608
EuPathDBiHostDB:ENSG00000182993.3
GeneCardsiC12orf60
HGNCiHGNC:28726 C12orf60
HPAiHPA043911
neXtProtiNX_Q5U649
OpenTargetsiENSG00000182993
PharmGKBiPA143485389
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFFE Eukaryota
ENOG4111DAN LUCA
GeneTreeiENSGT00390000003800
HOGENOMiHOG000111765
HOVERGENiHBG081242
InParanoidiQ5U649
OMAiPIMNLQL
OrthoDBiEOG091G0M4L
PhylomeDBiQ5U649
TreeFamiTF338464

Miscellaneous databases

ChiTaRSiC12orf60 human
GenomeRNAii144608
PROiPR:Q5U649

Gene expression databases

BgeeiENSG00000182993 Expressed in 149 organ(s), highest expression level in testis
CleanExiHS_C12orf60
GenevisibleiQ5U649 HS

Family and domain databases

InterProiView protein in InterPro
IPR027895 DUF4533
PfamiView protein in Pfam
PF15047 DUF4533, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCL060_HUMAN
AccessioniPrimary (citable) accession number: Q5U649
Secondary accession number(s): A8K1M7, Q5XKK8, Q8IXY2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: September 12, 2018
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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