Gata5

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
enhancer sequence-specific DNA binding Source: Ensembl
proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
RNA polymerase II proximal promoter sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Source: Ensembl
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

anatomical structure formation involved in morphogenesis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
animal organ morphogenesis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
aortic valve morphogenesis Source: Ensembl
cell development
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cellular response to BMP stimulus Source: Ensembl
endocardial cushion fusion Source: Ensembl
heart development
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
intestinal epithelial cell differentiation Source: Ensembl
negative regulation of cardiac muscle hypertrophy Source: Ensembl
negative regulation of gene expression Source: Ensembl
positive regulation of cardiac endothelial to mesenchymal transition Source: Ensembl
positive regulation of Notch signaling pathway involved in heart induction Source: Ensembl
positive regulation of transcription from RNA polymerase II promoter involved in heart development Source: Ensembl
tissue development
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: GATA-binding protein 5Imported Submitted name: Similar to Transcription factor GATA-5 (GATA binding factor-5)Imported
Gene namesⁱ	Name:Gata5Imported Synonyms:LOC499951Imported ORF Names:rCG_38545Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 3

Organism-specific databases

Rat genome database More...RGDⁱ	1561365 Gata5

RGDⁱ

1561365 Gata5

Subcellular locationⁱ

GO - Cellular component

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000058983 Expressed in 4 organ(s), highest expression level in heart

Bgeeⁱ

ENSRNOG00000058983 Expressed in 4 organ(s), highest expression level in heart

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000007896

STRINGⁱ

10116.ENSRNOP00000007896

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	190 – 244	GATA-typeInterPro annotationAdd BLAST		55
Domainⁱ	244 – 297	GATA-typeInterPro annotationAdd BLAST		54

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1601 Eukaryota COG5641 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119221
HOGENOMⁱ	HOG000047700
HOVERGENⁱ	HBG051703
KEGG Orthology (KO) More...KOⁱ	K17896
OMAⁱ	WTAGPFD
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AUR
TreeFamⁱ	TF315391

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00202 ZnF_GATA, 2 hits
Gene3Dⁱ	3.30.50.10, 2 hits
InterProⁱ	View protein in InterPro IPR008013 GATA_N IPR016375 TF_GATA_4/5/6 IPR039355 Transcription_factor_GATA IPR000679 Znf_GATA IPR013088 Znf_NHR/GATA
PANTHERⁱ	PTHR10071 PTHR10071, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00320 GATA, 2 hits PF05349 GATA-N, 1 hit
PIRSFⁱ	PIRSF003028 TF_GATA_4/5/6, 1 hit
PRINTSⁱ	PR00619 GATAZNFINGER
SMARTⁱ	View protein in SMART SM00401 ZnF_GATA, 2 hits
PROSITEⁱ	View protein in PROSITE PS00344 GATA_ZN_FINGER_1, 2 hits PS50114 GATA_ZN_FINGER_2, 2 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5U2V0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MYQSLALAQS PGQGTYADSG PFLHSSGAGS PVFVAPTRVP SMLPYLPSCE 
        60         70         80         90        100
PGSQPPALAA HSSWTQAVSA ESSAFGSGSP HPPATHPPGA TAFPFAHSPS 
       110        120        130        140        150
GSGSGGSAGV RDGAAFQSAL LAREQYPTAL GRPMSASYPT TYPAYVSPDV 
       160        170        180        190        200
APSWTSGPFD SSILHGLQGR PGGLPGRRTT FVPDFLEEFP GEGRECVNCG 
       210        220        230        240        250
ALSTPLWRRD GTGHYLCNAC GLYHKMNGVN RPLVRPQKRL SSSRRSGLCC 
       260        270        280        290        300
SNCHTATTTL WRRNAEGEPV CNACGLYMKL HGVPRPLAMK KESIQTRKRK 
       310        320        330        340        350
PKNPAKIKGS SGSTANSTAS SPTLLNTESS ATTLKAESSL ASPGCAGPTI 
       360        370        380        390        400
TSQASSPADE SLASSHLEFK FEPEDFVFTS SSLSPQAGLS GVLRQEAWCA 

LALA

Length:404

Mass (Da):42,098

Last modified:December 7, 2004 - v1

Checksum:ⁱ3E235B571A59D8BD

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115322 Genomic DNA No translation available. BC085855 mRNA Translation: AAH85855.1 CH474066 Genomic DNA Translation: EDL88812.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001019487.1, NM_001024316.1
UniGeneⁱ	Rn.27175

Genome annotation databases

Ensemblⁱ	ENSRNOT00000089971; ENSRNOP00000073661; ENSRNOG00000058983
GeneIDⁱ	499951
KEGGⁱ	rno:499951

Protein	Similar proteins		Species	Score	Length	Source
Q5U2V0	transcription factor GATA-5		MESAU		406	UniRef90_Q5U2V0
Transcription factor GATA-5		CRIGR		406
Uncharacterized protein		NEOLE		404
UPI00038C44B7		MICOH		405
UPI00042AAD59		PERMB		404
+3

Protein	Similar proteins		Species	Score	Length	Source
Q5U2V0	Transcription factor GATA-5		HUMAN		397	UniRef50_Q9BWX5
Transcription factor GATA-5		MOUSE		404
Uncharacterized protein		CERAT		397
Uncharacterized protein		MACNE		397
GATA binding protein 5		PONAB		397
+45

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115322 Genomic DNA No translation available. BC085855 mRNA Translation: AAH85855.1 CH474066 Genomic DNA Translation: EDL88812.1
RefSeqⁱ	NP_001019487.1, NM_001024316.1
UniGeneⁱ	Rn.27175

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000007896

STRINGⁱ

10116.ENSRNOP00000007896

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000089971; ENSRNOP00000073661; ENSRNOG00000058983
GeneIDⁱ	499951
KEGGⁱ	rno:499951

Organism-specific databases

CTDⁱ	140628
RGDⁱ	1561365 Gata5

Phylogenomic databases

eggNOGⁱ	KOG1601 Eukaryota COG5641 LUCA
GeneTreeⁱ	ENSGT00760000119221
HOGENOMⁱ	HOG000047700
HOVERGENⁱ	HBG051703
KOⁱ	K17896
OMAⁱ	WTAGPFD
OrthoDBⁱ	EOG091G0AUR
TreeFamⁱ	TF315391

Enzyme and pathway databases

Reactomeⁱ	R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Gene expression databases

Bgeeⁱ	ENSRNOG00000058983 Expressed in 4 organ(s), highest expression level in heart

Bgeeⁱ

ENSRNOG00000058983 Expressed in 4 organ(s), highest expression level in heart

Family and domain databases

CDDⁱ	cd00202 ZnF_GATA, 2 hits
Gene3Dⁱ	3.30.50.10, 2 hits
InterProⁱ	View protein in InterPro IPR008013 GATA_N IPR016375 TF_GATA_4/5/6 IPR039355 Transcription_factor_GATA IPR000679 Znf_GATA IPR013088 Znf_NHR/GATA
PANTHERⁱ	PTHR10071 PTHR10071, 1 hit
Pfamⁱ	View protein in Pfam PF00320 GATA, 2 hits PF05349 GATA-N, 1 hit
PIRSFⁱ	PIRSF003028 TF_GATA_4/5/6, 1 hit
PRINTSⁱ	PR00619 GATAZNFINGER
SMARTⁱ	View protein in SMART SM00401 ZnF_GATA, 2 hits
PROSITEⁱ	View protein in PROSITE PS00344 GATA_ZN_FINGER_1, 2 hits PS50114 GATA_ZN_FINGER_2, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5U2V0_RAT
Accessionⁱ	Q5U2V0Primary (citable) accession number: Q5U2V0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 7, 2004
	Last sequence update:	December 7, 2004
	Last modified:	November 7, 2018
	This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5U2V0 (Q5U2V0_RAT)

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GATA-binding protein 5

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ