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Protein

Membrane-associated phosphatidylinositol transfer protein 1

Gene

Pitpnm1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport
LigandCalcium, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-1483226 Synthesis of PI

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Membrane-associated phosphatidylinositol transfer protein 1
Alternative name(s):
Phosphatidylinositol transfer protein, membrane-associated 1
Short name:
PITPnm 1
Pyk2 N-terminal domain-interacting receptor 2
Short name:
NIR-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pitpnm1
Synonyms:Nir2, Pitpnm
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Rat genome database

More...
RGDi
1306710 Pitpnm1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Lipid droplet, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002327401 – 1242Membrane-associated phosphatidylinositol transfer protein 1Add BLAST1242

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei59PhosphothreonineBy similarity1
Modified residuei282PhosphothreonineBy similarity1
Modified residuei287PhosphothreonineCombined sources1
Modified residuei300PhosphoserineCombined sources1
Modified residuei304PhosphoserineCombined sources1
Modified residuei319PhosphoserineBy similarity1
Modified residuei326PhosphoserineBy similarity1
Modified residuei329PhosphoserineBy similarity1
Modified residuei342PhosphoserineCombined sources1
Modified residuei345PhosphoserineCombined sources1
Modified residuei346PhosphoserineCombined sources1
Modified residuei373PhosphoserineCombined sources1
Modified residuei382Phosphoserine; by CDK1By similarity1
Modified residuei593PhosphoserineCombined sources1
Modified residuei600PhosphoserineCombined sources1
Modified residuei621PhosphoserineCombined sources1
Modified residuei894PhosphoserineBy similarity1
Modified residuei1209Omega-N-methylarginineBy similarity1
Modified residuei1235PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated on multiple sites by CDK1 at the onset of mitosis. Phosphorylation facilitates dissociation from the Golgi complex and is required for interaction with PLK1 (By similarity).By similarity
Phosphorylated on threonine residues upon treatment with oleic acid.By similarity
Phosphorylated on tyrosine residues by PTK2B.By similarity

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5U2N3

PRoteomics IDEntifications database

More...
PRIDEi
Q5U2N3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5U2N3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5U2N3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000018553 Expressed in 10 organ(s), highest expression level in brain

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5U2N3 RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PIK4CA and VAPB. Interacts with PTK2B via its C-terminus. Interacts with RHOA. Has higher affinity for the inactive, GDP-bound form of RHOA. The CDK1-phosphorylated form interacts with PLK1 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000025084

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5U2N3

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5U2N3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini684 – 878DDHDPROSITE-ProRule annotationAdd BLAST195

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi310 – 319Poly-Ser10

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3668 Eukaryota
COG5083 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161522

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000294231

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG052733

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5U2N3

Identification of Orthologs from Complete Genome Data

More...
OMAi
HWQDAGY

Database of Orthologous Groups

More...
OrthoDBi
122895at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5U2N3

TreeFam database of animal gene trees

More...
TreeFami
TF312967

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.530.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004177 DDHD_dom
IPR036412 HAD-like_sf
IPR031315 LNS2/PITP
IPR001666 PI_transfer
IPR023393 START-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10658 PTHR10658, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02862 DDHD, 1 hit
PF02121 IP_trans, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00391 PITRANSFER

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01127 DDHD, 1 hit
SM00775 LNS2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784 SSF56784, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51043 DDHD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5U2N3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIKEYHILL PMSLDEYQVA QLYMIQKKSR EESSGEGSGV EILANRPYTD
60 70 80 90 100
GPGGNGQYTH KVYHVGSHIP GWFRALLPKA ALQVEEESWN AYPYTRTRYT
110 120 130 140 150
CPFVEKFSIE IETYYLPDGG QQPNVFNLSG AERRQRILDT IDIVRDAVAP
160 170 180 190 200
GEYKAEEDPR LYRSVKTGRG PLADDWARTA AQTGPLMCAY KLCKVEFRYW
210 220 230 240 250
GMQAKIEQFI HDVGLRRVML RAHRQAWCWQ DEWIELSMAD IRALEEETAR
260 270 280 290 300
MLAQRMAKCN TGSEGPEAQT PGKPSTETQP GTRTAGTPDG PEAPPGPDAS
310 320 330 340 350
PDASFGKQWS SSSRSSYSSQ HGGGVSPQSL SEWRMQNIAR DSENSSEEEF
360 370 380 390 400
FDAHEGFSDS DEVFPKEMTK WNSNDFIDAF ASPTEVEGVP DPAIMATKGI
410 420 430 440 450
EDEARAPRDS EGLDGTGDLG VEACSVHALF LILHSGSILD SGPGDTNSKQ
460 470 480 490 500
ADVQTLSTAF EAVTRVHFPE ALGHVALRLV PCPPICAAAY ALVSNLSPYS
510 520 530 540 550
HDGDSLSRSQ DHIPLAALPL LATSSSRYQG AVATVIARTN QAYAAFLRSS
560 570 580 590 600
EGTGFCGQVV LIGDGVGGIL GFDALCHSAS AGTGSRGSSR RGSMNNEMLS
610 620 630 640 650
PEVGPVRDPL ADGVEVLGRA SPEPSALPAQ RTSSDMANPD PDGSQNSLQV
660 670 680 690 700
APTVTSGEPR RASTASCPPA SSEAPDGPTN AARLDFKVSG FFLFGSPLGL
710 720 730 740 750
VLALRKTVMP ALEVAQMRPA CEQIYNLFHA ADPCASRLEP LLAPKFQAIA
760 770 780 790 800
PLAVPRYQKF PLGDGSSLLL ADTLQTHSSL FLEELEMMVP STPTSASGAF
810 820 830 840 850
WKGNELGNEP AAQPAAPSTT SEVVKILDRW WGNKRIDYSL YCPEALTAFP
860 870 880 890 900
TVTLPHLFHA SYWESADVVA FILRQVIEKE RPQLTECEEP SIYSPAFPRE
910 920 930 940 950
KWQRKRTQVK IRNVTSNHRA SDTVVCEGRP QVLNGRFMYG PLDVVTLTGE
960 970 980 990 1000
KVDVYVMTQP LSGKWIHFGT EVTNSSGRLT FPVPSERALG IGVYPVRMVV
1010 1020 1030 1040 1050
RGDHTYAECC LTVVSRGTEA VVFSIDGSFT ASVSIMGSDP KVRAGAVDVV
1060 1070 1080 1090 1100
RHWQDSGYLI VYVTGRPDMQ KHRVVAWLSQ HNFPHGVVSF CDGLTHDPLR
1110 1120 1130 1140 1150
QKAMFLQSLV QEVELNIVAG YGSPKDVAVY AALGLSPSQT YIVGRAVRKL
1160 1170 1180 1190 1200
QAQCQFLSDG YVAHLGQLEA GSHSHAPSGP PRAALAKSSY AVAAPVDFLR
1210 1220 1230 1240
KQSQLLRSRG PSQVDLEGPG TPPTTLARGK TRSISLKLDS EE
Length:1,242
Mass (Da):134,984
Last modified:December 7, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAEC9040877E2979E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC085945 mRNA Translation: AAH85945.1

NCBI Reference Sequences

More...
RefSeqi
NP_001008370.1, NM_001008369.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Rn.154692

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000025084; ENSRNOP00000025084; ENSRNOG00000018553

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
361694

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:361694

UCSC genome browser

More...
UCSCi
RGD:1306710 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085945 mRNA Translation: AAH85945.1
RefSeqiNP_001008370.1, NM_001008369.1
UniGeneiRn.154692

3D structure databases

ProteinModelPortaliQ5U2N3
SMRiQ5U2N3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025084

PTM databases

iPTMnetiQ5U2N3
PhosphoSitePlusiQ5U2N3

Proteomic databases

PaxDbiQ5U2N3
PRIDEiQ5U2N3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000025084; ENSRNOP00000025084; ENSRNOG00000018553
GeneIDi361694
KEGGirno:361694
UCSCiRGD:1306710 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9600
RGDi1306710 Pitpnm1

Phylogenomic databases

eggNOGiKOG3668 Eukaryota
COG5083 LUCA
GeneTreeiENSGT00940000161522
HOGENOMiHOG000294231
HOVERGENiHBG052733
InParanoidiQ5U2N3
OMAiHWQDAGY
OrthoDBi122895at2759
PhylomeDBiQ5U2N3
TreeFamiTF312967

Enzyme and pathway databases

ReactomeiR-RNO-1483226 Synthesis of PI

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5U2N3

Gene expression databases

BgeeiENSRNOG00000018553 Expressed in 10 organ(s), highest expression level in brain
GenevisibleiQ5U2N3 RN

Family and domain databases

Gene3Di3.30.530.20, 1 hit
InterProiView protein in InterPro
IPR004177 DDHD_dom
IPR036412 HAD-like_sf
IPR031315 LNS2/PITP
IPR001666 PI_transfer
IPR023393 START-like_dom_sf
PANTHERiPTHR10658 PTHR10658, 1 hit
PfamiView protein in Pfam
PF02862 DDHD, 1 hit
PF02121 IP_trans, 1 hit
PRINTSiPR00391 PITRANSFER
SMARTiView protein in SMART
SM01127 DDHD, 1 hit
SM00775 LNS2, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
PROSITEiView protein in PROSITE
PS51043 DDHD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPITM1_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5U2N3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: December 7, 2004
Last modified: January 16, 2019
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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