UniProtKB - Q5U231 (ZFR_XENTR)
Protein
Zinc finger RNA-binding protein
Gene
zfr
Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Functioni
Involved in postimplantation and gastrulation stages of development. Binds to DNA and RNA (By similarity).By similarity
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- double-stranded RNA binding Source: GO_Central
- single-stranded RNA binding Source: GO_Central
- zinc ion binding Source: InterPro
GO - Biological processi
- multicellular organism development Source: UniProtKB-KW
Keywordsi
Molecular function | Developmental protein, DNA-binding, RNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger RNA-binding protein |
Gene namesi | Name:zfr |
Organismi | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
Taxonomic identifieri | 8364 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana |
Proteomesi |
|
Organism-specific databases
Xenbasei | XB-GENE-6067390, zfr |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000312725 | 1 – 1065 | Zinc finger RNA-binding proteinAdd BLAST | 1065 |
Proteomic databases
PRIDEi | Q5U231 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 694 – 1064 | DZFPROSITE-ProRule annotationAdd BLAST | 371 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 35 – 302 | Ala-richAdd BLAST | 268 | |
Compositional biasi | 429 – 486 | Ser-richAdd BLAST | 58 |
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG3792, Eukaryota |
GeneTreei | ENSGT00940000155290 |
InParanoidi | Q5U231 |
OMAi | HDYVEEX |
OrthoDBi | 612611at2759 |
Family and domain databases
Gene3Di | 3.30.460.10, 1 hit |
InterProi | View protein in InterPro IPR006561, DZF_dom IPR003604, Matrin/U1-like-C_Znf_C2H2 IPR043519, NT_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF07528, DZF, 1 hit |
SMARTi | View protein in SMART SM00572, DZF, 1 hit SM00355, ZnF_C2H2, 3 hits SM00451, ZnF_U1, 3 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS51703, DZF, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All
Q5U231-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIPICPVVSF TYVPSRLGEE AKMATGNYFG FTHGAAAQYS QQPASGVAYS
60 70 80 90 100
HPTTVASYTV HQAPVAAHTV TAAYAPAAAT VAVARPAPVA VAAAATAAAY
110 120 130 140 150
GGYPAAHTAT DYGYTQRQQE APPPPPPVTT QNYQDSYSYV RSTAPAVAYD
160 170 180 190 200
SKQYYQQPTA TVAAAAQPQP AVAETYYQTA PIALSLPVAP KAGYSQGAAQ
210 220 230 240 250
YTQAQQTRQV TAIKPANPSP ATTTFSIYPV SSTVQPVAAA ATVVPSYTQS
260 270 280 290 300
ATYSTTAVTY SGAAYSGYEA AVYSAASSYY QQQQQQQQKQ AAAAAAAAAT
310 320 330 340 350
AAWTGTNFTK KPQFQNKQLK PKQPPKPPQI HYCDVCKISC AGPQTYKEHL
360 370 380 390 400
EGQKHKKKEA ALKASQNTTS SSTAVRGTQN QLRCELCDVS CTGADAYAAH
410 420 430 440 450
IRGAKHQKVV KLHTKLGKPI PSTEPNVVSQ SVTSAAVSKP STTSSSTSGA
460 470 480 490 500
NGSSSVGASP SVKLLTSSSS LSTSSSSKAS SMSSTSIVKK VTTPKITFIG
510 520 530 540 550
GNKLQSTGNK VDDSKMSDSA KTTPSTAAQT QEAKIDPMSE AAQTLAALQS
560 570 580 590 600
DVQPVGHDYV EEVRNDEGKV IRFHCKLCEC SFNDPNAKEM HLKGRRHRLQ
610 620 630 640 650
YKKKVNPDLQ VEVKPSIRAR KIQEEKMRKQ MQKEEYWRRR EEEERWRMEM
660 670 680 690 700
RRYEEDMYWR RMEEEQHHWD DRRRVPEGGY PHGPPGPPGL LGVRPGMPPQ
710 720 730 740 750
PQGPSPLRRP DSSDDRYVMT KHAAIYPTEE ELQAVQKIVS LTERALKLVS
760 770 780 790 800
DSMADQDKSK TKESDDKKEP SKERALKGVL RVGVLAKGLL LRGDRNVSLV
810 820 830 840 850
LLCAEKPTRA LLSRITESLP KQLAVICPEK YEVSCSLAEA AIILNSCVEP
860 870 880 890 900
KMQVTITLTS PVIREENLRD GDVTPGMVKD PPDVLDRQKC LDALAALRHA
910 920 930 940 950
KWFQARANGL QSCVIIIRIL RDLCQRVPTW SDFPSWALEL LVEKAISSSS
960 970 980 990 1000
GPQSPGDALR RVFECISSGI ILKGGPGLLD PCEKDPYDTL ATMNDQQRED
1010 1020 1030 1040 1050
ITSSAQFALR LLAFRQIYKV LGMDPLSQMN QRFNVHNNRK RRRDSDGVDS
1060
FEAEGKKDKK DYDNF
Computationally mapped potential isoform sequencesi
There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF6XPE8 | F6XPE8_XENTR | Ubiquitin carboxyl-terminal hydrola... | usp13 zfr | 843 | Annotation score: | ||
A0A7D9NKG7 | A0A7D9NKG7_XENTR | Ubiquitin carboxyl-terminal hydrola... | usp13 | 858 | Annotation score: | ||
A0A6I8PYF9 | A0A6I8PYF9_XENTR | Ubiquitin carboxyl-terminal hydrola... | usp13 | 844 | Annotation score: | ||
A0A6I8RMC6 | A0A6I8RMC6_XENTR | Ubiquitin carboxyl-terminal hydrola... | usp13 | 841 | Annotation score: | ||
A0A6I8SJP8 | A0A6I8SJP8_XENTR | Ubiquitin carboxyl-terminal hydrola... | usp13 | 855 | Annotation score: | ||
A0A6I8RGS9 | A0A6I8RGS9_XENTR | Ubiquitinyl hydrolase 1 | usp13 | 774 | Annotation score: | ||
A0A6I8QBR6 | A0A6I8QBR6_XENTR | Zinc finger RNA-binding protein | zfr | 1,050 | Annotation score: | ||
A0A6I8QY67 | A0A6I8QY67_XENTR | Ubiquitin carboxyl-terminal hydrola... | usp13 | 506 | Annotation score: | ||
A0A6I8R378 | A0A6I8R378_XENTR | Zinc finger RNA-binding protein | zfr | 880 | Annotation score: | ||
A0A6I8RLH1 | A0A6I8RLH1_XENTR | Zinc finger RNA-binding protein | zfr | 1,066 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC086301 mRNA Translation: AAH86301.1 |
RefSeqi | NP_001011177.1, NM_001011177.1 XP_012816351.1, XM_012960897.2 |
Genome annotation databases
Ensembli | ENSXETT00000034043; ENSXETP00000034043; ENSXETG00000015598 |
GeneIDi | 496597 |
KEGGi | xtr:496597 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC086301 mRNA Translation: AAH86301.1 |
RefSeqi | NP_001011177.1, NM_001011177.1 XP_012816351.1, XM_012960897.2 |
3D structure databases
SMRi | Q5U231 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 8364.ENSXETP00000034043 |
Proteomic databases
PRIDEi | Q5U231 |
Genome annotation databases
Ensembli | ENSXETT00000034043; ENSXETP00000034043; ENSXETG00000015598 |
GeneIDi | 496597 |
KEGGi | xtr:496597 |
Organism-specific databases
CTDi | 51663 |
Xenbasei | XB-GENE-6067390, zfr |
Phylogenomic databases
eggNOGi | KOG3792, Eukaryota |
GeneTreei | ENSGT00940000155290 |
InParanoidi | Q5U231 |
OMAi | HDYVEEX |
OrthoDBi | 612611at2759 |
Gene expression databases
ExpressionAtlasi | Q5U231, baseline |
Family and domain databases
Gene3Di | 3.30.460.10, 1 hit |
InterProi | View protein in InterPro IPR006561, DZF_dom IPR003604, Matrin/U1-like-C_Znf_C2H2 IPR043519, NT_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF07528, DZF, 1 hit |
SMARTi | View protein in SMART SM00572, DZF, 1 hit SM00355, ZnF_C2H2, 3 hits SM00451, ZnF_U1, 3 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS51703, DZF, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ZFR_XENTR | |
Accessioni | Q5U231Primary (citable) accession number: Q5U231 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 4, 2007 |
Last sequence update: | December 7, 2004 | |
Last modified: | April 7, 2021 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |