Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Rac family small GTPase 2

Gene

Rac2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: GO_Central
  • GTP binding Source: GO_Central
  • protein kinase regulator activity Source: Ensembl

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-114604 GPVI-mediated activation cascade
R-RNO-194840 Rho GTPase cycle
R-RNO-4086400 PCP/CE pathway
R-RNO-416482 G alpha (12/13) signalling events
R-RNO-5668599 RHO GTPases Activate NADPH Oxidases

Names & Taxonomyi

Protein namesi
Submitted name:
Rac family small GTPase 2Imported
Submitted name:
Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2)Imported
Gene namesi
Name:Rac2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1307568 Rac2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000007350 Expressed in 10 organ(s), highest expression level in spleen

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009994

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00760000118978
HOGENOMiHOG000233974
HOVERGENiHBG009351
KOiK07860
OMAiLCPQPAK
OrthoDBiEOG091G0KCM
TreeFamiTF101109

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit

Sequencei

Sequence statusi: Complete.

Q5U1Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP
60 70 80 90 100
VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE
110 120 130 140 150
VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKDID
160 170 180 190
SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRPCS LL
Length:192
Mass (Da):21,441
Last modified:December 7, 2004 - v1
Checksum:i2A1F1266AB9D7705
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058502 Genomic DNA No translation available.
BC086399 mRNA Translation: AAH86399.1
RefSeqiNP_001008385.1, NM_001008384.1
XP_006242090.1, XM_006242028.2
UniGeneiRn.2863

Genome annotation databases

EnsembliENSRNOT00000009994; ENSRNOP00000009994; ENSRNOG00000007350
GeneIDi366957
KEGGirno:366957
UCSCiRGD:1307568 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058502 Genomic DNA No translation available.
BC086399 mRNA Translation: AAH86399.1
RefSeqiNP_001008385.1, NM_001008384.1
XP_006242090.1, XM_006242028.2
UniGeneiRn.2863

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009994

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000009994; ENSRNOP00000009994; ENSRNOG00000007350
GeneIDi366957
KEGGirno:366957
UCSCiRGD:1307568 rat

Organism-specific databases

CTDi5880
RGDi1307568 Rac2

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00760000118978
HOGENOMiHOG000233974
HOVERGENiHBG009351
KOiK07860
OMAiLCPQPAK
OrthoDBiEOG091G0KCM
TreeFamiTF101109

Enzyme and pathway databases

ReactomeiR-RNO-114604 GPVI-mediated activation cascade
R-RNO-194840 Rho GTPase cycle
R-RNO-4086400 PCP/CE pathway
R-RNO-416482 G alpha (12/13) signalling events
R-RNO-5668599 RHO GTPases Activate NADPH Oxidases

Gene expression databases

BgeeiENSRNOG00000007350 Expressed in 10 organ(s), highest expression level in spleen

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U1Y2_RAT
AccessioniPrimary (citable) accession number: Q5U1Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: November 7, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again