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UniProtKB - Q5U1P8 (Q5U1P8_ORYSJ)
Protein
Peroxidase
Gene
prx45
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
UniRule annotationCatalytic activityi
- EC:1.11.1.7UniRule annotationARBA annotation
Cofactori
Protein has several cofactor binding sites:- Ca2+UniRule annotationNote: Binds 2 calcium ions per subunit.UniRule annotation
- heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 66 | Transition state stabilizerUniRule annotation | 1 | |
Active sitei | 70 | Proton acceptorUniRule annotation | 1 | |
Metal bindingi | 71 | Calcium 1UniRule annotation | 1 | |
Metal bindingi | 74 | Calcium 1; via carbonyl oxygenUniRule annotation | 1 | |
Metal bindingi | 76 | Calcium 1; via carbonyl oxygenUniRule annotation | 1 | |
Metal bindingi | 78 | Calcium 1UniRule annotation | 1 | |
Metal bindingi | 80 | Calcium 1UniRule annotation | 1 | |
Metal bindingi | 93 | Calcium 1UniRule annotation | 1 | |
Binding sitei | 170 | Substrate; via carbonyl oxygenUniRule annotation | 1 | |
Metal bindingi | 200 | Iron (heme axial ligand)UniRule annotation | 1 | |
Metal bindingi | 201 | Calcium 2UniRule annotation | 1 | |
Metal bindingi | 251 | Calcium 2UniRule annotation | 1 | |
Metal bindingi | 254 | Calcium 2UniRule annotation | 1 | |
Metal bindingi | 259 | Calcium 2UniRule annotation | 1 |
GO - Molecular functioni
- heme binding Source: UniProtKB-UniRule
- metal ion binding Source: UniProtKB-UniRule
- peroxidase activity Source: GO_Central
GO - Biological processi
- hydrogen peroxide catabolic process Source: UniProtKB-KW
- response to oxidative stress Source: UniProtKB-UniRule
Keywordsi
Molecular function | Oxidoreductase, Peroxidase |
Biological process | Hydrogen peroxideUniRule annotation |
Ligand | CalciumUniRule annotationARBA annotation, HemeUniRule annotationARBA annotation, Iron, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: PeroxidaseUniRule annotationARBA annotation (EC:1.11.1.7UniRule annotationARBA annotation) |
Gene namesi | Name:prx45Imported Ordered Locus Names:LOC_Os03g25330Imported, Os03g0368900Imported ORF Names:OSNPB_030368900Imported |
Organismi | Oryza sativa subsp. japonica (Rice)Imported |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
- Secreted UniRule annotation
Cell Wall
- plant-type cell wall Source: GO_Central
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedUniRule annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | UniRule annotationAdd BLAST | 24 | |
ChainiPRO_5013420909 | 25 – 332 | PeroxidaseUniRule annotationAdd BLAST | 308 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 39 ↔ 120 | UniRule annotation | ||
Disulfide bondi | 72 ↔ 77 | UniRule annotation | ||
Disulfide bondi | 126 ↔ 327 | UniRule annotation | ||
Disulfide bondi | 207 ↔ 235 | UniRule annotation |
Keywords - PTMi
Disulfide bondUniRule annotationARBA annotation, Pyrrolidone carboxylic acidARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 331 | PEROXIDASE_4InterPro annotationAdd BLAST | 303 |
Sequence similaritiesi
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.UniRule annotation
Keywords - Domaini
SignalUniRule annotationPhylogenomic databases
eggNOGi | ENOG502QPX7, Eukaryota |
HOGENOMi | CLU_010543_0_1_1 |
OMAi | SPYYPLE |
OrthoDBi | 902776at2759 |
Family and domain databases
CDDi | cd00693, secretory_peroxidase, 1 hit |
InterProi | View protein in InterPro IPR002016, Haem_peroxidase IPR010255, Haem_peroxidase_sf IPR000823, Peroxidase_pln IPR019794, Peroxidases_AS IPR019793, Peroxidases_heam-ligand_BS IPR033905, Secretory_peroxidase |
PANTHERi | PTHR31235, PTHR31235, 1 hit |
Pfami | View protein in Pfam PF00141, peroxidase, 1 hit |
PRINTSi | PR00458, PEROXIDASE PR00461, PLPEROXIDASE |
SUPFAMi | SSF48113, SSF48113, 1 hit |
PROSITEi | View protein in PROSITE PS00435, PEROXIDASE_1, 1 hit PS00436, PEROXIDASE_2, 1 hit PS50873, PEROXIDASE_4, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5U1P8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASSPSLPLV TCALLLLLAV ACQAHPYWPL ELAYYRDKCP QAEAVVKAVV
60 70 80 90 100
GEAVRQNPGN GAAVIRMLFH DCFVEGCDAS ILLDPTPFNP TPEKLSAPNN
110 120 130 140 150
PSMRGFDLID AIKHAVEAAC PGVVSCADII AFAARDATYF LSGGKVYFDM
160 170 180 190 200
PSGRRDGTFS NDSGPIDFLP PPTSNLSDLV SSFAVKGLSV EDMVVLSGAH
210 220 230 240 250
TVGRSHCSSF VPDRLNASVF SDIDGGFAWF LRSQCPLDAT PGGNDPTVML
260 270 280 290 300
DFVTPNTLDN QYYKNVLDHK VLFTSDAALL TSPETAKMVV DNAVIPGWWE
310 320 330
DRFKAAMVKL ASIQVKTGYQ GQIRKNCRVI NY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DP000009 Genomic DNA Translation: ABF96157.1 AK099751 mRNA Translation: BAG94279.1 AK120411 mRNA Translation: BAG99999.1 AP014959 Genomic DNA Translation: BAS84348.1 BN000574 Genomic DNA Translation: CAH69287.1 |
RefSeqi | XP_015632331.1, XM_015776845.1 |
Genome annotation databases
EnsemblPlantsi | Os03t0368900-01; Os03t0368900-01; Os03g0368900 |
GeneIDi | 4332925 |
Gramenei | Os03t0368900-01; Os03t0368900-01; Os03g0368900 |
KEGGi | osa:4332925 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DP000009 Genomic DNA Translation: ABF96157.1 AK099751 mRNA Translation: BAG94279.1 AK120411 mRNA Translation: BAG99999.1 AP014959 Genomic DNA Translation: BAS84348.1 BN000574 Genomic DNA Translation: CAH69287.1 |
RefSeqi | XP_015632331.1, XM_015776845.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 39947.Q5U1P8 |
Genome annotation databases
EnsemblPlantsi | Os03t0368900-01; Os03t0368900-01; Os03g0368900 |
GeneIDi | 4332925 |
Gramenei | Os03t0368900-01; Os03t0368900-01; Os03g0368900 |
KEGGi | osa:4332925 |
Phylogenomic databases
eggNOGi | ENOG502QPX7, Eukaryota |
HOGENOMi | CLU_010543_0_1_1 |
OMAi | SPYYPLE |
OrthoDBi | 902776at2759 |
Family and domain databases
CDDi | cd00693, secretory_peroxidase, 1 hit |
InterProi | View protein in InterPro IPR002016, Haem_peroxidase IPR010255, Haem_peroxidase_sf IPR000823, Peroxidase_pln IPR019794, Peroxidases_AS IPR019793, Peroxidases_heam-ligand_BS IPR033905, Secretory_peroxidase |
PANTHERi | PTHR31235, PTHR31235, 1 hit |
Pfami | View protein in Pfam PF00141, peroxidase, 1 hit |
PRINTSi | PR00458, PEROXIDASE PR00461, PLPEROXIDASE |
SUPFAMi | SSF48113, SSF48113, 1 hit |
PROSITEi | View protein in PROSITE PS00435, PEROXIDASE_1, 1 hit PS00436, PEROXIDASE_2, 1 hit PS50873, PEROXIDASE_4, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5U1P8_ORYSJ | |
Accessioni | Q5U1P8Primary (citable) accession number: Q5U1P8 Secondary accession number(s): Q9FRD8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 7, 2004 |
Last sequence update: | December 7, 2004 | |
Last modified: | January 19, 2022 | |
This is version 152 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |