UniProtKB - Q5U0I6 (Q5U0I6_HUMAN)
Protein
Submitted name:
H.sapiens ras-related Hrab1A protein
Gene
RAB1A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: InterPro
GO - Biological processi
- cell migration Source: Ensembl
- melanosome transport Source: Ensembl
- substrate adhesion-dependent cell spreading Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: H.sapiens ras-related Hrab1A proteinImportedSubmitted name: RAB1A proteinImportedSubmitted name: RAB1A, member RAS oncogene familyImportedSubmitted name: RAB1A, member RAS oncogene family, isoform CRA_bImportedSubmitted name: cDNA, FLJ96558, Homo sapiens RAB1A, member RAS oncogene family (RAB1A), mRNAImported |
Gene namesi | Name:RAB1AImported ORF Names:hCG_22592Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000138069.16 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus Source: Ensembl
Other locations
- melanosome Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSG00000138069, Expressed in sperm and 251 other tissues |
ExpressionAtlasi | Q5U0I6, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 178 – 205 | DisorderedSequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 187 – 205 | PolarSequence analysisAdd BLAST | 19 |
Phylogenomic databases
HOGENOMi | CLU_041217_23_1_1 |
OMAi | KERMGNT |
OrthoDBi | 1149105at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5U0I6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI
60 70 80 90 100
RTIELDGKTI KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDVTDQESFN
110 120 130 140 150
NVKQWLQEID RYASENVNKL LVGNKCDLTT KKVVDYTTAK EFADSLGIPF
160 170 180 190 200
LETSAKNATN VEQSFMTMAA EIKKRMGPGA TAGGAEKSNV KIQSTPVKQS
GGGCC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT019528 mRNA Translation: AAV38335.1 BT019529 mRNA Translation: AAV38336.1 AK315495 mRNA Translation: BAG37879.1 X13898 mRNA Translation: CAA32098.1 CR536488 mRNA Translation: CAG38727.1 CH471053 Genomic DNA Translation: EAW99918.1 CH471053 Genomic DNA Translation: EAW99922.1 |
RefSeqi | NP_004152.1, NM_004161.4 |
Genome annotation databases
GeneIDi | 5861 |
KEGGi | hsa:5861 |
UCSCi | uc002sdm.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT019528 mRNA Translation: AAV38335.1 BT019529 mRNA Translation: AAV38336.1 AK315495 mRNA Translation: BAG37879.1 X13898 mRNA Translation: CAA32098.1 CR536488 mRNA Translation: CAG38727.1 CH471053 Genomic DNA Translation: EAW99918.1 CH471053 Genomic DNA Translation: EAW99922.1 |
RefSeqi | NP_004152.1, NM_004161.4 |
3D structure databases
SMRi | Q5U0I6 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q5U0I6, 2 interactors |
Proteomic databases
MaxQBi | Q5U0I6 |
PRIDEi | Q5U0I6 |
Protocols and materials databases
Antibodypediai | 3942, 169 antibodies |
DNASUi | 5861 |
Genome annotation databases
GeneIDi | 5861 |
KEGGi | hsa:5861 |
UCSCi | uc002sdm.4, human |
Organism-specific databases
CTDi | 5861 |
PharmGKBi | PA34107 |
VEuPathDBi | HostDB:ENSG00000138069.16 |
Phylogenomic databases
HOGENOMi | CLU_041217_23_1_1 |
OMAi | KERMGNT |
OrthoDBi | 1149105at2759 |
Miscellaneous databases
BioGRID-ORCSi | 5861, 123 hits in 899 CRISPR screens |
ChiTaRSi | RAB1A, human |
GenomeRNAii | 5861 |
Gene expression databases
Bgeei | ENSG00000138069, Expressed in sperm and 251 other tissues |
ExpressionAtlasi | Q5U0I6, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5U0I6_HUMAN | |
Accessioni | Q5U0I6Primary (citable) accession number: Q5U0I6 Secondary accession number(s): D6W5F3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | February 10, 2021 | |
This is version 153 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |