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Protein
Submitted name:

Casein kinase 1 epsilon

Gene

CSNK1E

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Casein kinase 1 epsilonImported
Submitted name:
Casein kinase 1, epsilonImported
Submitted name:
HCG2014051, isoform CRA_aImported
Gene namesi
Name:CSNK1EImported
ORF Names:hCG_2014051Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000213923.10

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26953

PTM / Processingi

Proteomic databases

MaxQBiQ5U045

Expressioni

Gene expression databases

BgeeiENSG00000213923
ExpressionAtlasiQ5U045 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ5U045, 1 interactor
MINTiQ5U045

Structurei

3D structure databases

SMRiQ5U045
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 277Protein kinaseInterPro annotationAdd BLAST269

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1164 Eukaryota
ENOG410XPGP LUCA
HOVERGENiHBG000176
KOiK08960
OrthoDBiEOG091G0AFG

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q5U045-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH
60 70 80 90 100
IESKFYKMMQ GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF
110 120 130 140 150
SLKTVLLLAD QMISRIEYIH SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF
160 170 180 190 200
GLAKKYRDAR THQHIPYREN KNLTGTARYA SINTHLGIEQ SRRDDLESLG
210 220 230 240 250
YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL CKGYPSEFST
260 270 280 290 300
YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN
310 320 330 340 350
PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS
360 370 380 390 400
TPASRIQPAG NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS
410
RIPASQTSVP FDHLGK
Length:416
Mass (Da):47,315
Last modified:May 10, 2005 - v1
Checksum:iEE1B1698AE914324
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019831 mRNA Translation: AAV38634.1
EF015901 Genomic DNA Translation: ABM64212.1
CH471095 Genomic DNA Translation: EAW60228.1
CH471095 Genomic DNA Translation: EAW60230.1
CH471095 Genomic DNA Translation: EAW60232.1
CH471095 Genomic DNA Translation: EAW60233.1
CH471095 Genomic DNA Translation: EAW60234.1
RefSeqiNP_001276841.1, NM_001289912.1
NP_001885.1, NM_001894.4
NP_689407.1, NM_152221.2
UniGeneiHs.474833
Hs.720223

Genome annotation databases

GeneIDi102800317
1454
KEGGihsa:102800317
hsa:1454
UCSCiuc003avj.4 human

Similar proteinsi

Entry informationi

Entry nameiQ5U045_HUMAN
AccessioniPrimary (citable) accession number: Q5U045
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 20, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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