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Protein
Submitted name:

Cytochrome P450, family 2, subfamily AD, polypeptide 3

Gene

cyp2ad3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-DRE-211935 Fatty acids
R-DRE-211981 Xenobiotics
R-DRE-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 2, subfamily AD, polypeptide 3Imported
Submitted name:
Cytochrome P450, family 2, subfamily J, polypeptide 27Imported
Gene namesi
Name:cyp2ad3Imported
Synonyms:cyp2j27Imported, si:dkey-183n20.10Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 20

Organism-specific databases

ZFINiZDB-GENE-041001-156 cyp2ad3

Expressioni

Gene expression databases

BgeeiENSDARG00000022650 Expressed in 17 organ(s), highest expression level in embryo

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140799
HOVERGENiHBG015789
KOiK17852
OMAiPLMYLRV

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR008067 Cyt_P450_E_grp-I_CYP2A-like
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR01684 EP450ICYP2A
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q5TZ78-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILQFIYENF DFKSWILLGF GLLLLVDLIK YWNPSSFPPG PRPLPFLGNV
60 70 80 90 100
FTEIQDFRNI NKLAQVYGTI FSLRLGSEKL IIVSGYKMAK EALVTQNDSF
110 120 130 140 150
IDRPNVPLFH KVFKGLGTIL SNGYLWRMHR KFAVSHLRNF GVGNESLEVK
160 170 180 190 200
IQQECIFLCD AFKAEKGPVD PMVTLNSAIS NIISSLIFGQ RFDYHDEYYQ
210 220 230 240 250
RILRLDTECI QLAGSPRAQL YNACPWLFEY LPGPHQTIFS NYKKIKDFLR
260 270 280 290 300
GEIIKHREDW DPANPRDFID NYLTEMERKK SDPEAGFNIE GLVVTCLDLI
310 320 330 340 350
EAGTETATTT LRWGLLFMIK FPEIQEKVQA EIDRVIGQSR QPCLNDRVNM
360 370 380 390 400
PYTEAVIHEI QRFGDVVPLG FPKRAVKDTQ LGKYFIPKGT AITVNLSSVL
410 420 430 440 450
HDPNEWETPD TFNPGHFLDE IGQFRKRDAF MPFSAGKRAC LGENLARQEL
460 470 480 490
FLYFTSLLQQ FKISKCPGEE PSLEGEIWFT YAPAPFHICV SSR
Length:493
Mass (Da):56,644
Last modified:December 7, 2004 - v1
Checksum:i8A74E6CEFBF01AF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX322665 Genomic DNA No translation available.
BC134877 mRNA Translation: AAI34878.1
RefSeqiNP_001020725.1, NM_001025554.2
UniGeneiDr.85615

Genome annotation databases

EnsembliENSDART00000063081; ENSDARP00000063080; ENSDARG00000022650
GeneIDi569245
KEGGidre:569245

Similar proteinsi

Entry informationi

Entry nameiQ5TZ78_DANRE
AccessioniPrimary (citable) accession number: Q5TZ78
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 12, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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