UniProtKB - Q5THU2 (Q5THU2_HUMAN)
Protein
Submitted name:
Androgen-induced gene 1 protein
Gene
AIG1
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- 12-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 12-hydroxyoctadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 12-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 12-hydroxyoctadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 12-hexadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + H+ + hexadecanoateARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 12-octadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + H+ + octadecanoateARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 13-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 13-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 13-octadecanoyloxy-octadecanoate + H2O = 13-hydroxy-octadecanoate + H+ + octadecanoateARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 9-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 9-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 9-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- This reaction proceeds in the forwardARBA annotation direction.
- This reaction proceeds in the forwardARBA annotation direction.
Names & Taxonomyi
Protein namesi | Submitted name: Androgen-induced gene 1 proteinImported |
Gene namesi | Name:AIG1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:21607, AIG1 |
VEuPathDBi | HostDB:ENSG00000146416.16 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5004261948 | 19 – 47 | Sequence analysisAdd BLAST | 29 |
Proteomic databases
MaxQBi | Q5THU2 |
PeptideAtlasi | Q5THU2 |
ProteomicsDBi | 65170 |
Expressioni
Gene expression databases
Bgeei | ENSG00000146416, Expressed in liver and 223 other tissues |
ExpressionAtlasi | Q5THU2, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the AIG1 family.ARBA annotation
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158696 |
HOGENOMi | CLU_217051_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR006838, Far-17a_AIG1 |
PANTHERi | PTHR10989, PTHR10989, 1 hit |
Pfami | View protein in Pfam PF04750, Far-17a_AIG1, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q5THU2-1 [UniParc]FASTAAdd to basket
10 20 30 40
MALVPCQVLR MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDL
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NVV5 | AIG1_HUMAN | Androgen-induced gene 1 protein | AIG1 CGI-103 | 238 | Annotation score: | ||
Q5T2H0 | Q5T2H0_HUMAN | Androgen-induced gene 1 protein | AIG1 | 138 | Annotation score: | ||
Q5T2H4 | Q5T2H4_HUMAN | Androgen-induced gene 1 protein | AIG1 | 192 | Annotation score: | ||
Q5T2H3 | Q5T2H3_HUMAN | Androgen-induced gene 1 protein | AIG1 | 123 | Annotation score: | ||
A0A2R8YCJ8 | A0A2R8YCJ8_HUMAN | Androgen-induced gene 1 protein | AIG1 | 231 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. KF458306 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000367596; ENSP00000356568; ENSG00000146416 |
UCSCi | uc063ryt.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. KF458306 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | Q5THU2 |
PeptideAtlasi | Q5THU2 |
ProteomicsDBi | 65170 |
Protocols and materials databases
Antibodypediai | 53852, 143 antibodies |
Genome annotation databases
Ensembli | ENST00000367596; ENSP00000356568; ENSG00000146416 |
UCSCi | uc063ryt.1, human |
Organism-specific databases
HGNCi | HGNC:21607, AIG1 |
OpenTargetsi | ENSG00000146416 |
VEuPathDBi | HostDB:ENSG00000146416.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158696 |
HOGENOMi | CLU_217051_0_0_1 |
Miscellaneous databases
ChiTaRSi | AIG1, human |
Gene expression databases
Bgeei | ENSG00000146416, Expressed in liver and 223 other tissues |
ExpressionAtlasi | Q5THU2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006838, Far-17a_AIG1 |
PANTHERi | PTHR10989, PTHR10989, 1 hit |
Pfami | View protein in Pfam PF04750, Far-17a_AIG1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5THU2_HUMAN | |
Accessioni | Q5THU2Primary (citable) accession number: Q5THU2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 21, 2004 |
Last sequence update: | December 21, 2004 | |
Last modified: | February 10, 2021 | |
This is version 88 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |