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Protein
Submitted name:

Interferon gamma receptor 1

Gene

IFNGR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon gamma receptor 1Imported
Gene namesi
Name:IFNGR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000027697.12
HGNCiHGNC:5439 IFNGR1

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000027697

PTM / Processingi

Proteomic databases

MaxQBiQ5TFD1
PeptideAtlasiQ5TFD1
PRIDEiQ5TFD1

Expressioni

Gene expression databases

BgeeiENSG00000027697 Expressed in 241 organ(s), highest expression level in upper lobe of lung
ExpressionAtlasiQ5TFD1 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5TFD1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 102Fibronectin type-IIIInterPro annotationAdd BLAST90

Phylogenomic databases

eggNOGiENOG410IG11 Eukaryota
ENOG411218K LUCA
GeneTreeiENSGT00510000048929
HOGENOMiHOG000202211
HOVERGENiHBG102347

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR008355 Interferon_gamma_rcpt_asu
PANTHERiPTHR20859:SF5 PTHR20859:SF5, 1 hit
PfamiView protein in Pfam
PF01108 Tissue_fac, 1 hit
SUPFAMiSSF49265 SSF49265, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q5TFD1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLKSPENSL LQFQFKYGVP TPTNVTIESY NMNPIVYWEY QIMPQVPVFT
60 70 80 90 100
VEVKNYGVKN SEWIDACINI SHHYCNISDH VGDPSNSLWV RVKARVGQKE
110 120 130 140 150
SAYAKSEEFA VCRDGKIGPP KLDIRKEEKQ IMIDIFHPSV FVNGDEQEVD
160
YDPETTCYIR V
Length:161
Mass (Da):18,580
Last modified:December 21, 2004 - v1
Checksum:i8CE33C2B49E6964D
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P15260INGR1_HUMAN
Interferon gamma receptor 1
IFNGR1
489Annotation score:
Q5TFC9Q5TFC9_HUMAN
Interferon gamma receptor 1
IFNGR1
210Annotation score:
A0A2R8Y4U4A0A2R8Y4U4_HUMAN
Interferon gamma receptor 1
IFNGR1
479Annotation score:
A0A2R8YFL3A0A2R8YFL3_HUMAN
Interferon gamma receptor 1
IFNGR1
448Annotation score:
A0A2R8Y7R1A0A2R8Y7R1_HUMAN
Interferon gamma receptor 1
IFNGR1
470Annotation score:
A0A2R8Y792A0A2R8Y792_HUMAN
Interferon gamma receptor 1
IFNGR1
30Annotation score:
A0A2R8YEN6A0A2R8YEN6_HUMAN
Interferon gamma receptor 1
IFNGR1
27Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei161Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL050337 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000414770; ENSP00000394230; ENSG00000027697
UCSCiuc063rtw.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL050337 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5TFD1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ5TFD1
PeptideAtlasiQ5TFD1
PRIDEiQ5TFD1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000414770; ENSP00000394230; ENSG00000027697
UCSCiuc063rtw.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000027697.12
HGNCiHGNC:5439 IFNGR1
OpenTargetsiENSG00000027697
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG11 Eukaryota
ENOG411218K LUCA
GeneTreeiENSGT00510000048929
HOGENOMiHOG000202211
HOVERGENiHBG102347

Miscellaneous databases

ChiTaRSiIFNGR1 human

Gene expression databases

BgeeiENSG00000027697 Expressed in 241 organ(s), highest expression level in upper lobe of lung
ExpressionAtlasiQ5TFD1 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR008355 Interferon_gamma_rcpt_asu
PANTHERiPTHR20859:SF5 PTHR20859:SF5, 1 hit
PfamiView protein in Pfam
PF01108 Tissue_fac, 1 hit
SUPFAMiSSF49265 SSF49265, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ5TFD1_HUMAN
AccessioniPrimary (citable) accession number: Q5TFD1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 12, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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