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Protein

Protein SOGA3

Gene

SOGA3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SOGA3
Gene namesi
Name:SOGA3
Synonyms:C6orf174
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000214338.10
HostDB:ENSG00000255330.9
HGNCiHGNC:21494 SOGA3
neXtProtiNX_Q5TF21

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei915 – 935HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000214338
ENSG00000255330
PharmGKBiPA134983080

Polymorphism and mutation databases

BioMutaiSOGA3
DMDMi74746351

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000027135222 – 947Protein SOGA3Add BLAST926

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei569PhosphoserineBy similarity1
Modified residuei781PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ5TF21
MaxQBiQ5TF21
PaxDbiQ5TF21
PeptideAtlasiQ5TF21
PRIDEiQ5TF21
ProteomicsDBi65069

PTM databases

iPTMnetiQ5TF21
PhosphoSitePlusiQ5TF21

Expressioni

Gene expression databases

BgeeiENSG00000214338
CleanExiHS_C6orf174
ExpressionAtlasiQ5TF21 baseline and differential
GenevisibleiQ5TF21 HS

Organism-specific databases

HPAiHPA035388
HPA035389

Interactioni

Protein-protein interaction databases

BioGridi132241, 11 interactors
STRINGi9606.ENSP00000455908

Structurei

3D structure databases

ProteinModelPortaliQ5TF21
SMRiQ5TF21
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili342 – 726Sequence analysisAdd BLAST385
Coiled coili811 – 835Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi72 – 81Poly-Gln10
Compositional biasi82 – 247Gly-richAdd BLAST166
Compositional biasi269 – 276Poly-Ala8

Sequence similaritiesi

Belongs to the SOGA family.Curated

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4787 Eukaryota
ENOG410XUHJ LUCA
GeneTreeiENSGT00530000063889
HOGENOMiHOG000111576
HOVERGENiHBG081115
InParanoidiQ5TF21
OMAiKSGGHES
OrthoDBiEOG091G03VQ
PhylomeDBiQ5TF21
TreeFamiTF331853

Family and domain databases

InterProiView protein in InterPro
IPR027881 SOGA
PfamiView protein in Pfam
PF11365 SOGA, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5TF21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQPPIGGAA PATAAASPAA AATEARLHPE GSSRKQQRAQ SPARPRDSSL
60 70 80 90 100
RQTIAATRSP VGAGTKLNSV RQQQLQQQQQ QGNKTGSRTG PPASIRGGGG
110 120 130 140 150
GAEKATPLAP KGAAPGAVQP VAGAEAAPAA TLAALGGRRP GPPEEPPREL
160 170 180 190 200
ESVPSKLGEP PPLGEGGGGG GEGGGAGGGS GEREGGAPQP PPPRGWRGKG
210 220 230 240 250
VRAQQRGGSG GEGASPSPSS SSAGKTPGTG SRNSGSGVAG GGSGGGGSYW
260 270 280 290 300
KEGCLQSELI QFHLKKERAA AAAAAAQMHA KNGGGSSSRS SPVSGPPAVC
310 320 330 340 350
ETLAVASASP MAAAAEGPQQ SAEGSASGGG MQAAAPPSSQ PHPQQLQEQE
360 370 380 390 400
EMQEEMEKLR EENETLKNEI DELRTEMDEM RDTFFEEDAC QLQEMRHELE
410 420 430 440 450
RANKNCRILQ YRLRKAERKR LRYAQTGEID GELLRSLEQD LKVAKDVSVR
460 470 480 490 500
LHHELENVEE KRTTTEDENE KLRQQLIEVE IAKQALQNEL EKMKELSLKR
510 520 530 540 550
RGSKDLPKSE KKAQQTPTEE DNEDLKCQLQ FVKEEAALMR KKMAKIDKEK
560 570 580 590 600
DRFEHELQKY RSFYGDLDSP LPKGEAGGPP STREAELKLR LRLVEEEANI
610 620 630 640 650
LGRKIVELEV ENRGLKAELD DLRGDDFNGS ANPLMREQSE SLSELRQHLQ
660 670 680 690 700
LVEDETELLR RNVADLEEQN KRITAELNKY KYKSGGHDSA RHHDNAKTEA
710 720 730 740 750
LQEELKAARL QINELSGKVM QLQYENRVLM SNMQRYDLAS HLGIRGSPRD
760 770 780 790 800
SDAESDAGKK ESDDDSRPPH RKREGPIGGE SDSEEVRNIR CLTPTRSFYP
810 820 830 840 850
APGPWPKSFS DRQQMKDIRS EAERLGKTID RLIADTSTII TEARIYVANG
860 870 880 890 900
DLFGLMDEED DGSRIREHEL LYRINAQMKA FRKELQTFID RLEVPKSADD
910 920 930 940
RGAEEPISVS QMFQPIILLI LILVLFSSLS YTTIFKLVFL FTLFFVL
Length:947
Mass (Da):103,199
Last modified:December 21, 2004 - v1
Checksum:iC920C1D4369F1737
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096711 Genomic DNA No translation available.
CCDSiCCDS43505.1
RefSeqiNP_001012279.1, NM_001012279.2
UniGeneiHs.319247

Genome annotation databases

EnsembliENST00000525778; ENSP00000434570; ENSG00000214338
GeneIDi387104
KEGGihsa:387104
UCSCiuc003qbd.3 human

Similar proteinsi

Entry informationi

Entry nameiSOGA3_HUMAN
AccessioniPrimary (citable) accession number: Q5TF21
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 21, 2004
Last modified: July 18, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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