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Protein
Submitted name:

Importin subunit alpha-6

Gene

KPNA5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Importin subunit alpha-6Imported
Gene namesi
Name:KPNA5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000196911.9
HGNCiHGNC:6398 KPNA5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196911

PTM / Processingi

Proteomic databases

MaxQBiQ5TD90
PeptideAtlasiQ5TD90
PRIDEiQ5TD90

Expressioni

Gene expression databases

BgeeiENSG00000196911 Expressed in 212 organ(s), highest expression level in neocortex
ExpressionAtlasiQ5TD90 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5TD90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 57IBBInterPro annotationAdd BLAST57

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
GeneTreeiENSGT00760000119094
HOGENOMiHOG000202210
HOVERGENiHBG056013

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
PfamiView protein in Pfam
PF01749 IBB, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51214 IBB, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5TD90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPGKDNYR MKSYKNKALN PQEMRRRREE EGIQLRKQKR EEQLFKRRNV
60 70 80 90 100
YLPRNDESML ESPIQDPDIS STVPIPEEEV VTTDMVQMIF SNNADQQLTA
110 120 130 140
TQKFRKLLSK EPNPPIDQVI QKPGVVQRFV KFLERNENCT LQ
Length:142
Mass (Da):16,765
Last modified:December 21, 2004 - v1
Checksum:iD28D91F7268EDC72
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15131IMA6_HUMAN
Importin subunit alpha-6
KPNA5
536Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132795 Genomic DNA No translation available.
AL354716 Genomic DNA No translation available.
KF458260 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000413340; ENSP00000396791; ENSG00000196911
UCSCiuc063qyg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132795 Genomic DNA No translation available.
AL354716 Genomic DNA No translation available.
KF458260 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5TD90
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ5TD90
PeptideAtlasiQ5TD90
PRIDEiQ5TD90

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413340; ENSP00000396791; ENSG00000196911
UCSCiuc063qyg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000196911.9
HGNCiHGNC:6398 KPNA5
OpenTargetsiENSG00000196911
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
GeneTreeiENSGT00760000119094
HOGENOMiHOG000202210
HOVERGENiHBG056013

Miscellaneous databases

ChiTaRSiKPNA5 human

Gene expression databases

BgeeiENSG00000196911 Expressed in 212 organ(s), highest expression level in neocortex
ExpressionAtlasiQ5TD90 baseline and differential

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
PfamiView protein in Pfam
PF01749 IBB, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51214 IBB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5TD90_HUMAN
AccessioniPrimary (citable) accession number: Q5TD90
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 12, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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