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Protein

Collagen alpha-1(XIII) chain

Gene

COL13A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. At neuromuscular junctions, may play a role in acetylcholine receptor clustering (PubMed:26626625).By similarity3 Publications

GO - Molecular functioni

  • extracellular matrix structural constituent Source: GO_Central
  • extracellular matrix structural constituent conferring tensile strength Source: BHF-UCL
  • heparin binding Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, Heparin-binding
Biological processCell adhesion, Differentiation, Osteogenesis

Enzyme and pathway databases

ReactomeiR-HSA-1442490 Collagen degradation
R-HSA-1650814 Collagen biosynthesis and modifying enzymes
R-HSA-216083 Integrin cell surface interactions
R-HSA-8948216 Collagen chain trimerization

Names & Taxonomyi

Protein namesi
Recommended name:
Collagen alpha-1(XIII) chain
Alternative name(s):
COLXIIIA1
Gene namesi
Name:COL13A1Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000197467.13
HGNCiHGNC:2190 COL13A1
MIMi120350 gene
neXtProtiNX_Q5TAT6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 44CytoplasmicSequence analysisAdd BLAST44
Transmembranei45 – 61Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST17
Topological domaini62 – 717ExtracellularSequence analysisAdd BLAST656

Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

Pathology & Biotechi

Involvement in diseasei

Myasthenic syndrome, congenital, 19 (CMS19)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of congenital myasthenic syndrome, a group of disorders characterized by failure of neuromuscular transmission, including pre-synaptic, synaptic, and post-synaptic disorders that are not of autoimmune origin. Clinical features are easy fatigability and muscle weakness affecting the axial and limb muscles (with hypotonia in early-onset forms), the ocular muscles (leading to ptosis and ophthalmoplegia), and the facial and bulbar musculature (affecting sucking and swallowing, and leading to dysphonia). The symptoms fluctuate and worsen with physical effort.
See also OMIM:616720

Keywords - Diseasei

Congenital myasthenic syndrome

Organism-specific databases

DisGeNETi1305
MalaCardsiCOL13A1
MIMi616720 phenotype
OpenTargetsiENSG00000197467
Orphaneti98913 Postsynaptic congenital myasthenic syndromes
98914 Presynaptic congenital myasthenic syndromes
PharmGKBiPA26706

Polymorphism and mutation databases

BioMutaiCOL13A1
DMDMi74745860

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002846791 – 717Collagen alpha-1(XIII) chainAdd BLAST717

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ5TAT6
PeptideAtlasiQ5TAT6
PRIDEiQ5TAT6
ProteomicsDBi64863
64864 [Q5TAT6-10]
64865 [Q5TAT6-2]
64866 [Q5TAT6-3]
64867 [Q5TAT6-4]
64868 [Q5TAT6-5]
64869 [Q5TAT6-6]
64870 [Q5TAT6-7]
64871 [Q5TAT6-8]
64872 [Q5TAT6-9]

PTM databases

iPTMnetiQ5TAT6
PhosphoSitePlusiQ5TAT6

Expressioni

Tissue specificityi

Widely expressed in both fetal and adult ocular tissues (at protein level). In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands. Isoform 10: Expressed in muscle (PubMed:26626625).3 Publications

Gene expression databases

BgeeiENSG00000197467 Expressed in 176 organ(s), highest expression level in tibia
ExpressionAtlasiQ5TAT6 baseline and differential
GenevisibleiQ5TAT6 HS

Organism-specific databases

HPAiHPA050392

Interactioni

Subunit structurei

Homotrimer; disulfide-linked. Nucleation of the type XIII collagen triple helix is likely to occur at the N-terminal region with triple helix formation proceeding from the N- to the C-terminus. Interacts with FN1, perlecan/HSPG2 and NID2.2 Publications

Protein-protein interaction databases

BioGridi107701, 1 interactor
ComplexPortaliCPX-1754 Collagen type XIII trimer
STRINGi9606.ENSP00000381949

Structurei

3D structure databases

ProteinModelPortaliQ5TAT6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 121Nonhelical region 1 (NC1)Sequence analysisAdd BLAST121
Regioni122 – 216Triple-helical region 1 (COL1)Sequence analysisAdd BLAST95
Regioni217 – 269Nonhelical region 2 (NC2)Sequence analysisAdd BLAST53
Regioni270 – 441Triple-helical region 2 (COL2)Sequence analysisAdd BLAST172
Regioni442 – 463Nonhelical region 3 (NC3)Sequence analysisAdd BLAST22
Regioni464 – 699Triple-helical region 3 (COL3)Sequence analysisAdd BLAST236
Regioni700 – 717Nonhelical region 4 (NC4)Sequence analysisAdd BLAST18

Keywords - Domaini

Collagen, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IS74 Eukaryota
ENOG410YPXK LUCA
GeneTreeiENSGT00900000140850
HOGENOMiHOG000085653
HOVERGENiHBG004933
InParanoidiQ5TAT6
KOiK16617
OMAiSPGCHCP
OrthoDBiEOG091G0C0U
PhylomeDBiQ5TAT6
TreeFamiTF338175

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
PfamiView protein in Pfam
PF01391 Collagen, 9 hits

Sequences (11+)i

Sequence statusi: Complete.

This entry describes 11 isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms seem to exist.Curated

This entry has 11 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 11 Publication (identifier: Q5TAT6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVAERTHKAA ATGARGPGEL GAPGTVALVA ARAERGARLP SPGSCGLLTL
60 70 80 90 100
ALCSLALSLL AHFRTAELQA RVLRLEAERG EQQMETAILG RVNQLLDEKW
110 120 130 140 150
KLHSRRRREA PKTSPGCNCP PGPPGPTGRP GLPGDKGAIG MPGRVGSPGD
160 170 180 190 200
AGLSIIGPRG PPGQPGTRGF PGFPGPIGLD GKPGHPGPKG DMGLTGPPGQ
210 220 230 240 250
PGPQGQKGEK GQCGEYPHRE CLSSMPAALR SSQIIALKLL PLLNSVRLAP
260 270 280 290 300
PPVIKRRTFQ GEQSQASIQG PPGPPGPPGP SGPLGHPGLP GPMGPPGLPG
310 320 330 340 350
PPGPKGDPGI QGYHGRKGER GMPGMPGKHG AKGAPGIAVA GMKGEPGIPG
360 370 380 390 400
TKGEKGAEGS PGLPGLLGQK GEKGDAGNSI GGGRGEPGPP GLPGPPGPKG
410 420 430 440 450
EAGVDGQVGP PGQPGDKGER GAAGEQGPDG PKGSKGEPGK GEMVDYNGNI
460 470 480 490 500
NEALQEIRTL ALMGPPGLPG QIGPPGAPGI PGQKGEIGLP GPPGHDGEKG
510 520 530 540 550
PRGKPGDMGP PGPQGPPGKD GPPGVKGENG HPGSPGEKGE KGETGQAGSP
560 570 580 590 600
GEKGEAGEKG NPGAEVPGLP GPEGPPGPPG LQGVPGPKGE AGLDGAKGEK
610 620 630 640 650
GFQGEKGDRG PLGLPGASGL DGRPGPPGTP GPIGVPGPAG PKGERGSKGD
660 670 680 690 700
PGMTGPTGAA GLPGLHGPPG DKGNRGERGK KGSRGPKGDK GDQGAPGLDA
710
PCPLGEDGLP VQGCWNK
Length:717
Mass (Da):69,950
Last modified:December 21, 2004 - v1
Checksum:iFD12CA80CC93540F
GO
Isoform 21 Publication (identifier: Q5TAT6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     239-260: Missing.

Note: Gene prediction based on EST data.Curated
Show »
Length:695
Mass (Da):67,439
Checksum:i9816F7BCDD8C108B
GO
Isoform 31 Publication (identifier: Q5TAT6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     239-260: Missing.
     617-628: Missing.

Note: Gene prediction based on EST data.Curated
Show »
Length:683
Mass (Da):66,377
Checksum:i3BB550FD03062C30
GO
Isoform 41 Publication (identifier: Q5TAT6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     239-260: Missing.
     551-565: Missing.
     617-628: Missing.

Show »
Length:668
Mass (Da):64,965
Checksum:iAAC18C9E4B45DA4E
GO
Isoform 51 Publication (identifier: Q5TAT6-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     551-565: Missing.

Show »
Length:702
Mass (Da):68,538
Checksum:i66FC08083E0D4A91
GO
Isoform 61 Publication (identifier: Q5TAT6-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     566-579: Missing.

Show »
Length:703
Mass (Da):68,700
Checksum:i62947B1FEEBF6268
GO
Isoform 71 Publication (identifier: Q5TAT6-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     566-579: Missing.
     617-628: Missing.

Show »
Length:691
Mass (Da):67,638
Checksum:iEEC688B6A5364877
GO
Isoform 81 Publication (identifier: Q5TAT6-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     220-238: Missing.
     617-628: Missing.

Show »
Length:686
Mass (Da):66,887
Checksum:i0256074DDF33E752
GO
Isoform 91 Publication (identifier: Q5TAT6-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     239-260: Missing.
     551-565: Missing.
     617-628: Missing.
     676-705: Missing.

Show »
Length:638
Mass (Da):62,077
Checksum:iE172A8ADA30B84DC
GO
Isoform 10 (identifier: Q5TAT6-10) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     122-159: Missing.
     220-238: Missing.
     551-565: Missing.

Note: No experimental confirmation available.
Show »
Length:645
Mass (Da):63,036
Checksum:i2BD4AF1794648BDA
GO
Isoform 11 (identifier: Q5TAT6-11) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     135-163: Missing.
     239-260: Missing.
     551-565: Missing.
     617-628: Missing.
     678-706: Missing.

Note: Gene prediction based on EST data.
Show »
Length:610
Mass (Da):59,465
Checksum:iDDDD4D432DD45849
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EX21E7EX21_HUMAN
Collagen alpha-1(XIII) chain
COL13A1
582Annotation score:
E7ES50E7ES50_HUMAN
Collagen alpha-1(XIII) chain
COL13A1
642Annotation score:
A0A2R8YGI3A0A2R8YGI3_HUMAN
Collagen alpha-1(XIII) chain
COL13A1
728Annotation score:
H7BYT9H7BYT9_HUMAN
Collagen alpha-1(XIII) chain
COL13A1
247Annotation score:
H7BZB6H7BZB6_HUMAN
Collagen alpha-1(XIII) chain
COL13A1
174Annotation score:

Sequence cautioni

The sequence AAA51685 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti182K → F in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti394G → A in CAC00688 (PubMed:11013208).Curated1
Sequence conflicti394G → A in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti466P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti466P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti469P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti469P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti475P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti475P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti478P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti478P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti480 – 481IP → ML in AAA51685 (PubMed:1698771).Curated2
Sequence conflicti480 – 481IP → ML in AAA52047 (PubMed:3547403).Curated2
Sequence conflicti490P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti490P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti493P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti493P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti498Missing in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti498Missing in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti505P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti505P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti511P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti511P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti517P → L in AAA51685 (PubMed:1698771).Curated1
Sequence conflicti517P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti570P → L in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti570P → L in AAA51987 (PubMed:2459707).Curated1
Sequence conflicti570P → L in AAA51990 (PubMed:2459707).Curated1
Sequence conflicti570P → L in AAA51991 (PubMed:2459707).Curated1
Sequence conflicti706E → Q in AAA52047 (PubMed:3547403).Curated1
Sequence conflicti706E → Q in AAA52048 (PubMed:3547403).Curated1
Sequence conflicti706E → Q in AAA51987 (PubMed:2459707).Curated1
Sequence conflicti706E → Q in AAA51988 (PubMed:2459707).Curated1
Sequence conflicti706E → Q in AAA51989 (PubMed:2459707).Curated1
Sequence conflicti706E → Q in AAA51990 (PubMed:2459707).Curated1
Sequence conflicti706E → Q in AAA51991 (PubMed:2459707).Curated1
Sequence conflicti709L → Y in AAA51987 (PubMed:2459707).Curated1
Sequence conflicti709L → Y in AAA51988 (PubMed:2459707).Curated1
Sequence conflicti709L → Y in AAA51989 (PubMed:2459707).Curated1
Sequence conflicti709L → Y in AAA51990 (PubMed:2459707).Curated1
Sequence conflicti709L → Y in AAA51991 (PubMed:2459707).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_055670531H → Q. Corresponds to variant dbSNP:rs1061954Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_043361122 – 159Missing in isoform 10. 1 PublicationAdd BLAST38
Alternative sequenceiVSP_047230135 – 163Missing in isoform 11. CuratedAdd BLAST29
Alternative sequenceiVSP_052382220 – 238Missing in isoform 8 and isoform 10. 2 PublicationsAdd BLAST19
Alternative sequenceiVSP_052383239 – 260Missing in isoform 2, isoform 3, isoform 4, isoform 9 and isoform 11. 1 PublicationAdd BLAST22
Alternative sequenceiVSP_052384551 – 565Missing in isoform 4, isoform 5, isoform 9, isoform 10 and isoform 11. 3 PublicationsAdd BLAST15
Alternative sequenceiVSP_052385566 – 579Missing in isoform 6 and isoform 7. 1 PublicationAdd BLAST14
Alternative sequenceiVSP_052386617 – 628Missing in isoform 3, isoform 4, isoform 7, isoform 8, isoform 9 and isoform 11. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_052387676 – 705Missing in isoform 9. 1 PublicationAdd BLAST30
Alternative sequenceiVSP_047231678 – 706Missing in isoform 11. CuratedAdd BLAST29

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ293624 mRNA Translation: CAC00688.1
AC024601 Genomic DNA No translation available.
AC025426 Genomic DNA No translation available.
AL138925 Genomic DNA No translation available.
BC136385 mRNA Translation: AAI36386.1
M59217 mRNA Translation: AAA51685.1 Different initiation.
M33653 mRNA Translation: AAA52047.1
M15524 mRNA Translation: AAA52048.1
M20803
, M20795, M20796, M20797, M20798, M20799, M20800, M20801, M20802, M20804, M20805 Genomic DNA Translation: AAA51987.1
M20803
, M20795, M20796, M20797, M20798, M20799, M20800, M20801, M20802, M20804 Genomic DNA Translation: AAA51988.1
M20803
, M20795, M20796, M20797, M20798, M20799, M20801, M20802, M20804 Genomic DNA Translation: AAA51989.1
M20803
, M20796, M20797, M20798, M20799, M20800, M20801, M20802, M20804, M20805 Genomic DNA Translation: AAA51990.1
M20803
, M20796, M20797, M20798, M20799, M20801, M20802, M20804, M20805 Genomic DNA Translation: AAA51991.1
CCDSiCCDS44419.1 [Q5TAT6-1]
CCDS44423.2 [Q5TAT6-4]
CCDS44424.2 [Q5TAT6-2]
CCDS44425.2 [Q5TAT6-8]
CCDS44427.2 [Q5TAT6-10]
CCDS44428.2 [Q5TAT6-11]
PIRiB40983
RefSeqiNP_001123575.1, NM_001130103.1 [Q5TAT6-1]
NP_542988.3, NM_080798.3 [Q5TAT6-10]
NP_542990.3, NM_080800.3 [Q5TAT6-8]
NP_542991.3, NM_080801.3 [Q5TAT6-2]
NP_542992.3, NM_080802.3 [Q5TAT6-4]
NP_542995.3, NM_080805.3 [Q5TAT6-11]
UniGeneiHs.695934

Genome annotation databases

EnsembliENST00000354547; ENSP00000346553; ENSG00000197467 [Q5TAT6-2]
ENST00000357811; ENSP00000350463; ENSG00000197467 [Q5TAT6-3]
ENST00000398978; ENSP00000381949; ENSG00000197467 [Q5TAT6-1]
ENST00000517713; ENSP00000430061; ENSG00000197467 [Q5TAT6-4]
ENST00000520133; ENSP00000430173; ENSG00000197467 [Q5TAT6-11]
ENST00000520267; ENSP00000428057; ENSG00000197467 [Q5TAT6-10]
ENST00000522165; ENSP00000428342; ENSG00000197467 [Q5TAT6-8]
GeneIDi1305
KEGGihsa:1305
UCSCiuc057tuj.1 human [Q5TAT6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ293624 mRNA Translation: CAC00688.1
AC024601 Genomic DNA No translation available.
AC025426 Genomic DNA No translation available.
AL138925 Genomic DNA No translation available.
BC136385 mRNA Translation: AAI36386.1
M59217 mRNA Translation: AAA51685.1 Different initiation.
M33653 mRNA Translation: AAA52047.1
M15524 mRNA Translation: AAA52048.1
M20803
, M20795, M20796, M20797, M20798, M20799, M20800, M20801, M20802, M20804, M20805 Genomic DNA Translation: AAA51987.1
M20803
, M20795, M20796, M20797, M20798, M20799, M20800, M20801, M20802, M20804 Genomic DNA Translation: AAA51988.1
M20803
, M20795, M20796, M20797, M20798, M20799, M20801, M20802, M20804 Genomic DNA Translation: AAA51989.1
M20803
, M20796, M20797, M20798, M20799, M20800, M20801, M20802, M20804, M20805 Genomic DNA Translation: AAA51990.1
M20803
, M20796, M20797, M20798, M20799, M20801, M20802, M20804, M20805 Genomic DNA Translation: AAA51991.1
CCDSiCCDS44419.1 [Q5TAT6-1]
CCDS44423.2 [Q5TAT6-4]
CCDS44424.2 [Q5TAT6-2]
CCDS44425.2 [Q5TAT6-8]
CCDS44427.2 [Q5TAT6-10]
CCDS44428.2 [Q5TAT6-11]
PIRiB40983
RefSeqiNP_001123575.1, NM_001130103.1 [Q5TAT6-1]
NP_542988.3, NM_080798.3 [Q5TAT6-10]
NP_542990.3, NM_080800.3 [Q5TAT6-8]
NP_542991.3, NM_080801.3 [Q5TAT6-2]
NP_542992.3, NM_080802.3 [Q5TAT6-4]
NP_542995.3, NM_080805.3 [Q5TAT6-11]
UniGeneiHs.695934

3D structure databases

ProteinModelPortaliQ5TAT6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi107701, 1 interactor
ComplexPortaliCPX-1754 Collagen type XIII trimer
STRINGi9606.ENSP00000381949

PTM databases

iPTMnetiQ5TAT6
PhosphoSitePlusiQ5TAT6

Polymorphism and mutation databases

BioMutaiCOL13A1
DMDMi74745860

Proteomic databases

PaxDbiQ5TAT6
PeptideAtlasiQ5TAT6
PRIDEiQ5TAT6
ProteomicsDBi64863
64864 [Q5TAT6-10]
64865 [Q5TAT6-2]
64866 [Q5TAT6-3]
64867 [Q5TAT6-4]
64868 [Q5TAT6-5]
64869 [Q5TAT6-6]
64870 [Q5TAT6-7]
64871 [Q5TAT6-8]
64872 [Q5TAT6-9]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000354547; ENSP00000346553; ENSG00000197467 [Q5TAT6-2]
ENST00000357811; ENSP00000350463; ENSG00000197467 [Q5TAT6-3]
ENST00000398978; ENSP00000381949; ENSG00000197467 [Q5TAT6-1]
ENST00000517713; ENSP00000430061; ENSG00000197467 [Q5TAT6-4]
ENST00000520133; ENSP00000430173; ENSG00000197467 [Q5TAT6-11]
ENST00000520267; ENSP00000428057; ENSG00000197467 [Q5TAT6-10]
ENST00000522165; ENSP00000428342; ENSG00000197467 [Q5TAT6-8]
GeneIDi1305
KEGGihsa:1305
UCSCiuc057tuj.1 human [Q5TAT6-1]

Organism-specific databases

CTDi1305
DisGeNETi1305
EuPathDBiHostDB:ENSG00000197467.13
GeneCardsiCOL13A1
H-InvDBiHIX0025928
HGNCiHGNC:2190 COL13A1
HPAiHPA050392
MalaCardsiCOL13A1
MIMi120350 gene
616720 phenotype
neXtProtiNX_Q5TAT6
OpenTargetsiENSG00000197467
Orphaneti98913 Postsynaptic congenital myasthenic syndromes
98914 Presynaptic congenital myasthenic syndromes
PharmGKBiPA26706
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IS74 Eukaryota
ENOG410YPXK LUCA
GeneTreeiENSGT00900000140850
HOGENOMiHOG000085653
HOVERGENiHBG004933
InParanoidiQ5TAT6
KOiK16617
OMAiSPGCHCP
OrthoDBiEOG091G0C0U
PhylomeDBiQ5TAT6
TreeFamiTF338175

Enzyme and pathway databases

ReactomeiR-HSA-1442490 Collagen degradation
R-HSA-1650814 Collagen biosynthesis and modifying enzymes
R-HSA-216083 Integrin cell surface interactions
R-HSA-8948216 Collagen chain trimerization

Miscellaneous databases

GeneWikiiCollagen,_type_XIII,_alpha_1
GenomeRNAii1305
PROiPR:Q5TAT6
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000197467 Expressed in 176 organ(s), highest expression level in tibia
ExpressionAtlasiQ5TAT6 baseline and differential
GenevisibleiQ5TAT6 HS

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
PfamiView protein in Pfam
PF01391 Collagen, 9 hits
ProtoNetiSearch...

Entry informationi

Entry nameiCODA1_HUMAN
AccessioniPrimary (citable) accession number: Q5TAT6
Secondary accession number(s): A6NFR5
, B9EGD2, E7EWL8, Q13992, Q13993, Q13994, Q13995, Q13996, Q5TAT4, Q5TAT5, Q7KZ33, Q7KZ49, Q99228, Q9NQ52
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 21, 2004
Last modified: November 7, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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