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Entry version 112 (16 Oct 2019)
Sequence version 1 (21 Dec 2004)
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Protein

Ceramide-1-phosphate transfer protein

Gene

CPTP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide. C1P transfer is stimulated by phosphatidylserine in C1P source vesicles (PubMed:28011644). Regulates autophagy, inflammasome mediated IL1B and IL18 processing, and pyroptosis, but not apoptosis (PubMed:29164996).3 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei56Phosphoceramide1 Publication1
Binding sitei60Phosphoceramide1 Publication1
Binding sitei106Phosphoceramide1 Publication1
Binding sitei110Phosphoceramide1 Publication1
Binding sitei150Phosphoceramide1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport
LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1660662 Glycosphingolipid metabolism

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000000406

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ceramide-1-phosphate transfer protein1 PublicationCurated
Short name:
CPTP1 PublicationCurated
Alternative name(s):
Glycolipid transfer protein domain-containing protein 1Curated
Short name:
GLTP domain-containing protein 11 PublicationCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CPTPImported
Synonyms:GLTPD11 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28116 CPTP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615467 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5TA50

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Endosome, Golgi apparatus, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi42F → A: Increases phosphoceramide transfer. 1 Publication1
Mutagenesisi43L → R: Nearly abolishes phosphoceramide transfer. 1 Publication1
Mutagenesisi50F → R: Slightly reduces phosphoceramide transfer. 1 Publication1
Mutagenesisi53I → N: Slightly decreases phosphoceramide transfer. 1 Publication1
Mutagenesisi56D → V: Slightly decreases phosphoceramide transfer. 1 Publication1
Mutagenesisi60K → A: Nearly abolishes phosphoceramide transfer. Induces autophagy in a dominant negatif manner. 2 Publications1
Mutagenesisi97R → L: No effect. 1 Publication1
Mutagenesisi106R → L: Nearly abolishes phosphoceramide transfer. Induces autophagy in a dominant negatif manner. 2 Publications1
Mutagenesisi110R → L: Reduces phosphoceramide transfer. 1 Publication1
Mutagenesisi113R → E or L: Strongly reduces phosphoceramide transfer. 1 Publication1
Mutagenesisi117W → A: Slightly reduces phosphoceramide transfer. 1 Publication1
Mutagenesisi118L → R: Abolishes phosphoceramide transfer. 1 Publication1
Mutagenesisi149Y → A: Reduces phosphoceramide transfer. 1 Publication1
Mutagenesisi158V → N: Abolishes phosphoceramide transfer. 1 Publication1

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000224051

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162389853

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5TA50

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CPTP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74745771

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003171561 – 214Ceramide-1-phosphate transfer proteinAdd BLAST214

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5TA50

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5TA50

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5TA50

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5TA50

PeptideAtlas

More...
PeptideAtlasi
Q5TA50

PRoteomics IDEntifications database

More...
PRIDEi
Q5TA50

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
64828

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5TA50

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000224051 Expressed in 221 organ(s), highest expression level in apex of heart

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5TA50 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5TA50 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA056832

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123305, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q5TA50, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000343890

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1214
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5TA50

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GLTP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4189 Eukaryota
ENOG4111NKT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161763

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000046738

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5TA50

Identification of Orthologs from Complete Genome Data

More...
OMAi
HPWVIRK

Database of Orthologous Groups

More...
OrthoDBi
1423493at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5TA50

TreeFam database of animal gene trees

More...
TreeFami
TF316097

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.3520.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036497 GLTP_sf
IPR014830 Glycolipid_transfer_prot_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08718 GLTP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF110004 SSF110004, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5TA50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDSETGFNL KVVLVSFKQC LDEKEEVLLD PYIASWKGLV RFLNSLGTIF
60 70 80 90 100
SFISKDVVSK LRIMERLRGG PQSEHYRSLQ AMVAHELSNR LVDLERRSHH
110 120 130 140 150
PESGCRTVLR LHRALHWLQL FLEGLRTSPE DARTSALCAD SYNASLAAYH
160 170 180 190 200
PWVVRRAVTV AFCTLPTREV FLEAMNVGPP EQAVQMLGEA LPFIQRVYNV
210
SQKLYAEHSL LDLP
Length:214
Mass (Da):24,365
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB66F4581FD9C60A0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KST3J3KST3_HUMAN
Ceramide-1-phosphate transfer prote...
CPTP
117Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence EAW56230 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR599582 mRNA No translation available.
AL139287 Genomic DNA No translation available.
CH471183 Genomic DNA Translation: EAW56230.1 Sequence problems.
BC098429 mRNA Translation: AAH98429.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30555.1

NCBI Reference Sequences

More...
RefSeqi
NP_001025056.1, NM_001029885.1
XP_005244858.1, XM_005244801.3
XP_011540502.1, XM_011542200.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000343938; ENSP00000343890; ENSG00000224051

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80772

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80772

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR599582 mRNA No translation available.
AL139287 Genomic DNA No translation available.
CH471183 Genomic DNA Translation: EAW56230.1 Sequence problems.
BC098429 mRNA Translation: AAH98429.1
CCDSiCCDS30555.1
RefSeqiNP_001025056.1, NM_001029885.1
XP_005244858.1, XM_005244801.3
XP_011540502.1, XM_011542200.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4K80X-ray2.05A1-214[»]
4K84X-ray1.90A/B1-214[»]
4K85X-ray1.90A/B/C/D1-214[»]
4K8NX-ray3.10A/B/C/D/E/F1-214[»]
4KBSX-ray1.90A/B1-214[»]
4KF6X-ray3.20A/B/C/D/E/F1-214[»]
SMRiQ5TA50
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi123305, 7 interactors
IntActiQ5TA50, 8 interactors
STRINGi9606.ENSP00000343890

Chemistry databases

SwissLipidsiSLP:000000406

PTM databases

iPTMnetiQ5TA50

Polymorphism and mutation databases

BioMutaiCPTP
DMDMi74745771

Proteomic databases

EPDiQ5TA50
jPOSTiQ5TA50
MassIVEiQ5TA50
PaxDbiQ5TA50
PeptideAtlasiQ5TA50
PRIDEiQ5TA50
ProteomicsDBi64828

Genome annotation databases

EnsembliENST00000343938; ENSP00000343890; ENSG00000224051
GeneIDi80772
KEGGihsa:80772

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80772

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CPTP
HGNCiHGNC:28116 CPTP
HPAiHPA056832
MIMi615467 gene
neXtProtiNX_Q5TA50
OpenTargetsiENSG00000224051
PharmGKBiPA162389853

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4189 Eukaryota
ENOG4111NKT LUCA
GeneTreeiENSGT00940000161763
HOGENOMiHOG000046738
InParanoidiQ5TA50
OMAiHPWVIRK
OrthoDBi1423493at2759
PhylomeDBiQ5TA50
TreeFamiTF316097

Enzyme and pathway databases

ReactomeiR-HSA-1660662 Glycosphingolipid metabolism

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80772
PharosiQ5TA50

Protein Ontology

More...
PROi
PR:Q5TA50

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000224051 Expressed in 221 organ(s), highest expression level in apex of heart
ExpressionAtlasiQ5TA50 baseline and differential
GenevisibleiQ5TA50 HS

Family and domain databases

Gene3Di1.10.3520.10, 1 hit
InterProiView protein in InterPro
IPR036497 GLTP_sf
IPR014830 Glycolipid_transfer_prot_dom
PfamiView protein in Pfam
PF08718 GLTP, 1 hit
SUPFAMiSSF110004 SSF110004, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPTP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5TA50
Secondary accession number(s): Q4G0E6, Q7L5A4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 21, 2004
Last modified: October 16, 2019
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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