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UniProtKB - Q5T9S5 (CCD18_HUMAN)

Entry version 112 (17 Jun 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Coiled-coil domain-containing protein 18

Gene

CCDC18

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 18
Alternative name(s):
Sarcoma antigen NY-SAR-24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC18
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000122483.17

Human Gene Nomenclature Database

More...HGNCi		HGNC:30370 CCDC18

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5T9S5

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		343099

Open Targets

More...OpenTargetsi		ENSG00000122483

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142672178

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5T9S5 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CCDC18

Domain mapping of disease mutations (DMDM)

More...DMDMi		74745727

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002847751 – 1454Coiled-coil domain-containing protein 18Add BLAST1454

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei45PhosphoserineBy similarity1
Modified residuei1355PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5T9S5

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5T9S5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5T9S5

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5T9S5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5T9S5

PeptideAtlas

More...PeptideAtlasi		Q5T9S5

PRoteomics IDEntifications database

More...PRIDEi		Q5T9S5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		64812 [Q5T9S5-1]
64813 [Q5T9S5-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5T9S5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5T9S5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000122483 Expressed in testis and 120 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5T9S5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5T9S5 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000122483 Tissue enhanced (lymphoid)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		131230, 36 interactors

Protein interaction database and analysis system

More...IntActi		Q5T9S5, 32 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000383808

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5T9S5 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5T9S5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili107 – 138Sequence analysisAdd BLAST32
Coiled coili170 – 402Sequence analysisAdd BLAST233
Coiled coili438 – 464Sequence analysisAdd BLAST27
Coiled coili508 – 1309Sequence analysisAdd BLAST802

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IJJN Eukaryota
ENOG4111YKF LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153190

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5T9S5

Database of Orthologous Groups

More...OrthoDBi		130835at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5T9S5

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029613 Ccdc18/Sojo

The PANTHER Classification System

More...PANTHERi		PTHR18875:SF8 PTHR18875:SF8, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T9S5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESSSSDYYN KDNEEESLLA NVASLRHELK ITEWSLQSLG EELSSVSPSE 
        60         70         80         90        100
NSDYAPNPSR SEKLILDVQP SHPGLLNYSP YENVCKISGS STDFQKKPRD 
       110        120        130        140        150
KMFSSSAPVD QEIKSLREKL NKLRQQNACL VTQNHSLMTK FESIHFELTQ 
       160        170        180        190        200
SRAKVSMLES AQQQAASVPI LEEQIINLEA EVSAQDKVLR EAENKLEQSQ 
       210        220        230        240        250
KMVIEKEQSL QESKEECIKL KVDLLEQTKQ GKRAERQRNE ALYNAEELSK 
       260        270        280        290        300
AFQQYKKKVA EKLEKVQAEE EILERNLTNC EKENKRLQER CGLYKSELEI 
       310        320        330        340        350
LKEKLRQLKE ENNNGKEKLR IMAVKNSEVM AQLTESRQSI LKLESELENK 
       360        370        380        390        400
DEILRDKFSL MNENRELKVR VAAQNERLDL CQQEIESSRV ELRSLEKIIS 
       410        420        430        440        450
QLPLKRELFG FKSYLSKYQM SSFSNKEDRC IGCCEANKLV ISELRIKLAI 
       460        470        480        490        500
KEAEIQKLHA NLTANQLSQS LITCNDSQES SKLSSLETEP VKLGGHQVES 
       510        520        530        540        550
VKDQNQHTMN KQYEKERQRL VTGIEELRTK LIQIEAENSD LKVNMAHRTS 
       560        570        580        590        600
QFQLIQEELL EKASNSSKLE SEMTKKCSQL LTLEKQLEEK IVAYSSIAAK 
       610        620        630        640        650
NAELEQELME KNEKIRSLET NINTEHEKIC LAFEKAKKIH LEQHKEMEKQ 
       660        670        680        690        700
IERLEAQLEK KDQQFKEQEK TMSMLQQDII CKQHHLESLD RLLTESKGEM 
       710        720        730        740        750
KKENMKKDEA LKALQNQVSE ETIKVRQLDS ALEICKEELV LHLNQLEGNK 
       760        770        780        790        800
EKFEKQLKKK SEEVYCLQKE LKIKNHSLQE TSEQNVILQH TLQQQQQMLQ 
       810        820        830        840        850
QETIRNGELE DTQTKLEKQV SKLEQELQKQ RESSAEKLRK MEEKCESAAH 
       860        870        880        890        900
EADLKRQKVI ELTGTARQVK IEMDQYKEEL SKMEKEIMHL KRDGENKAMH 
       910        920        930        940        950
LSQLDMILDQ TKTELEKKTN AVKELEKLQH STETELTEAL QKREVLETEL 
       960        970        980        990       1000
QNAHGELKST LRQLQELRDV LQKAQLSLEE KYTTIKDLTA ELRECKMEIE 
      1010       1020       1030       1040       1050
DKKQELLEMD QALKERNWEL KQRAAQVTHL DMTIREHRGE MEQKIIKLEG 
      1060       1070       1080       1090       1100
TLEKSELELK ECNKQIESLN DKLQNAKEQL REKEFIMLQN EQEISQLKKE 
      1110       1120       1130       1140       1150
IERTQQRMKE MESVMKEQEQ YIATQYKEAI DLGQELRLTR EQVQNSHTEL 
      1160       1170       1180       1190       1200
AEARHQQVQA QREIERLSSE LEDMKQLSKE KDAHGNHLAE ELGASKVREA 
      1210       1220       1230       1240       1250
HLEARMQAEI KKLSAEVESL KEAYHMEMIS HQENHAKWKI SADSQKSSVQ 
      1260       1270       1280       1290       1300
QLNEQLEKAK LELEEAQDTV SNLHQQVQDR NEVIEAANEA LLTKESELTR 
      1310       1320       1330       1340       1350
LQAKISGHEK AEDIKFLPAP FTSPTEIMPD VQDPKFAKCF HTSFSKCTKL 
      1360       1370       1380       1390       1400
RRSISASDLT FKIHGDEDLS EELLQDLKKM QLEQPSTLEE SHKNLTYTQP 
      1410       1420       1430       1440       1450
DSFKPLTYNL EADSSENNDF NTLSGMLRYI NKEVRLLKKS SMQTGAGLNQ 

GENV
Length:1,454
Mass (Da):168,962
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F2FB01956059DD1
GO
Isoform 2 (identifier: Q5T9S5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1295-1450: Missing.

Show »
Length:1,298
Mass (Da):151,249
Checksum:iEC2B08A1D2934319
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KP97J3KP97_HUMAN
Coiled-coil domain-containing prote...
CCDC18
1,508Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YCD6H0YCD6_HUMAN
Coiled-coil domain-containing prote...
CCDC18
443Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PFB9E9PFB9_HUMAN
Coiled-coil domain-containing prote...
CCDC18
1,299Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T9S2Q5T9S2_HUMAN
Coiled-coil domain-containing prote...
CCDC18
720Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C0C9H7C0C9_HUMAN
Coiled-coil domain-containing prote...
CCDC18
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YDP2H0YDP2_HUMAN
Coiled-coil domain-containing prote...
CCDC18
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC86410 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti326N → T in BAC86410 (PubMed:16710414).Curated1
Sequence conflicti498V → VA in BAC86410 (PubMed:16710414).Curated1
Sequence conflicti901L → F in BAC86410 (PubMed:16710414).Curated1
Sequence conflicti1002K → E in BAC86410 (PubMed:16710414).Curated1
Sequence conflicti1126Y → C in BAC86410 (PubMed:16710414).Curated1
Sequence conflicti1135E → K in BAC86410 (PubMed:16710414).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0246361295 – 1450Missing in isoform 2. 1 PublicationAdd BLAST156

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK126045 mRNA Translation: BAC86410.1 Different initiation.
AC126124 Genomic DNA No translation available.
AL139421 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS76180.1 [Q5T9S5-1]

NCBI Reference Sequences

More...RefSeqi		NP_001293005.1, NM_001306076.1 [Q5T9S5-1]
NP_996769.3, NM_206886.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000343253; ENSP00000343377; ENSG00000122483 [Q5T9S5-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		343099

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:343099

UCSC genome browser

More...UCSCi		uc057iix.1 human [Q5T9S5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126045 mRNA Translation: BAC86410.1 Different initiation.
AC126124 Genomic DNA No translation available.
AL139421 Genomic DNA No translation available.
CCDSiCCDS76180.1 [Q5T9S5-1]
RefSeqiNP_001293005.1, NM_001306076.1 [Q5T9S5-1]
NP_996769.3, NM_206886.4

3D structure databases

SMRiQ5T9S5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi131230, 36 interactors
IntActiQ5T9S5, 32 interactors
STRINGi9606.ENSP00000383808

PTM databases

iPTMnetiQ5T9S5
PhosphoSitePlusiQ5T9S5

Polymorphism and mutation databases

BioMutaiCCDC18
DMDMi74745727

Proteomic databases

EPDiQ5T9S5
jPOSTiQ5T9S5
MassIVEiQ5T9S5
MaxQBiQ5T9S5
PaxDbiQ5T9S5
PeptideAtlasiQ5T9S5
PRIDEiQ5T9S5
ProteomicsDBi64812 [Q5T9S5-1]
64813 [Q5T9S5-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		33656 46 antibodies

The DNASU plasmid repository

More...DNASUi		343099

Genome annotation databases

EnsembliENST00000343253; ENSP00000343377; ENSG00000122483 [Q5T9S5-1]
GeneIDi343099
KEGGihsa:343099
UCSCiuc057iix.1 human [Q5T9S5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		343099
DisGeNETi343099
EuPathDBiHostDB:ENSG00000122483.17

GeneCards: human genes, protein and diseases

More...GeneCardsi		CCDC18
HGNCiHGNC:30370 CCDC18
HPAiENSG00000122483 Tissue enhanced (lymphoid)
neXtProtiNX_Q5T9S5
OpenTargetsiENSG00000122483
PharmGKBiPA142672178

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IJJN Eukaryota
ENOG4111YKF LUCA
GeneTreeiENSGT00940000153190
InParanoidiQ5T9S5
OrthoDBi130835at2759
PhylomeDBiQ5T9S5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		343099 0 hits in 49 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CCDC18 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		343099
PharosiQ5T9S5 Tdark

Protein Ontology

More...PROi		PR:Q5T9S5
RNActiQ5T9S5 protein

Gene expression databases

BgeeiENSG00000122483 Expressed in testis and 120 other tissues
ExpressionAtlasiQ5T9S5 baseline and differential
GenevisibleiQ5T9S5 HS

Family and domain databases

InterProiView protein in InterPro
IPR029613 Ccdc18/Sojo
PANTHERiPTHR18875:SF8 PTHR18875:SF8, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCD18_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T9S5
Secondary accession number(s): Q6ZU17
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 21, 2004
Last modified: June 17, 2020
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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