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Protein
Submitted name:

Polycomb complex protein BMI-1

Gene

BMI1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Polycomb complex protein BMI-1Imported
Gene namesi
Name:BMI1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000168283.13
HGNCiHGNC:1066 BMI1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168283

PTM / Processingi

Proteomic databases

MaxQBiQ5T8Z6
PeptideAtlasiQ5T8Z6
PRIDEiQ5T8Z6

Expressioni

Gene expression databases

BgeeiENSG00000168283 Expressed in 234 organ(s), highest expression level in brain
ExpressionAtlasiQ5T8Z6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5T8Z6
SMRiQ5T8Z6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 57RING-typeInterPro annotationAdd BLAST40

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2660 Eukaryota
ENOG410XPCN LUCA
GeneTreeiENSGT00550000074463
HOGENOMiHOG000231946
HOVERGENiHBG071649

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR039642 E3_Ub_ligase/polycomb_RING
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR10825 PTHR10825, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q5T8Z6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS
60 70 80 90 100
KYCPICDVQV HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA

HPSAD
Length:105
Mass (Da):12,248
Last modified:December 21, 2004 - v1
Checksum:iB540DC3F35567B17
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P35226BMI1_HUMAN
Polycomb complex protein BMI-1
BMI1 PCGF4, RNF51
326Annotation score:
Q5T8Z2Q5T8Z2_HUMAN
Polycomb complex protein BMI-1
BMI1
184Annotation score:
Q5T8Z4Q5T8Z4_HUMAN
Polycomb complex protein BMI-1
BMI1
150Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei105Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158211 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000416820; ENSP00000399220; ENSG00000168283
UCSCiuc057sfk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158211 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5T8Z6
SMRiQ5T8Z6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ5T8Z6
PeptideAtlasiQ5T8Z6
PRIDEiQ5T8Z6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000416820; ENSP00000399220; ENSG00000168283
UCSCiuc057sfk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168283.13
HGNCiHGNC:1066 BMI1
OpenTargetsiENSG00000168283
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2660 Eukaryota
ENOG410XPCN LUCA
GeneTreeiENSGT00550000074463
HOGENOMiHOG000231946
HOVERGENiHBG071649

Gene expression databases

BgeeiENSG00000168283 Expressed in 234 organ(s), highest expression level in brain
ExpressionAtlasiQ5T8Z6 baseline and differential

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR039642 E3_Ub_ligase/polycomb_RING
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR10825 PTHR10825, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T8Z6_HUMAN
AccessioniPrimary (citable) accession number: Q5T8Z6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 7, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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