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Protein

RAB6-interacting golgin

Gene

GORAB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

It is uncertain whether Met-1 or Met-26 is the initiator.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RAB6-interacting golgin
Alternative name(s):
N-terminal kinase-like-binding protein 1
Short name:
NTKL-BP1
Short name:
NTKL-binding protein 1
Short name:
hNTKL-BP1
SCY1-like 1-binding protein 1
Short name:
SCYL1-BP1
Short name:
SCYL1-binding protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GORAB
Synonyms:NTKLBP1, SCYL1BP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000120370.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25676 GORAB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
607983 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5T7V8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Golgi apparatus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Geroderma osteodysplasticum (GO)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
See also OMIM:231070

Keywords - Diseasei

Dwarfism

Organism-specific databases

DisGeNET

More...
DisGeNETi
92344

MalaCards human disease database

More...
MalaCardsi
GORAB
MIMi231070 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000120370

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
2078 Geroderma osteodysplastica

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164720285

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GORAB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74745442

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002524441 – 394RAB6-interacting golginAdd BLAST394

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5T7V8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5T7V8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5T7V8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5T7V8

PeptideAtlas

More...
PeptideAtlasi
Q5T7V8

PRoteomics IDEntifications database

More...
PRIDEi
Q5T7V8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
64687
64688 [Q5T7V8-2]
64689 [Q5T7V8-3]
64690 [Q5T7V8-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5T7V8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5T7V8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000120370 Expressed in 189 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_SCYL1BP1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5T7V8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5T7V8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA027208
HPA027250

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.By similarity2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
MDM2Q009876EBI-3917143,EBI-389668

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124937, 20 interactors

Protein interaction database and analysis system

More...
IntActi
Q5T7V8, 59 interactors

Molecular INTeraction database

More...
MINTi
Q5T7V8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356737

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5T7V8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5T7V8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni213 – 394Necessary for interaction with RCHY11 PublicationAdd BLAST182

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili170 – 322Sequence analysisAdd BLAST153

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GORAB family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJC7 Eukaryota
ENOG4111VTM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014886

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112758

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5T7V8

KEGG Orthology (KO)

More...
KOi
K19748

Identification of Orthologs from Complete Genome Data

More...
OMAi
MKLKRIQ

Database of Orthologous Groups

More...
OrthoDBi
1277705at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5T7V8

TreeFam database of animal gene trees

More...
TreeFami
TF324839

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007033 GORAB

The PANTHER Classification System

More...
PANTHERi
PTHR21470 PTHR21470, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04949 Transcrip_act, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T7V8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSWAAVLAVA AARFGHFWGC RWPGPMAQGW AGFSEEELRR LKQTKDPFEP
60 70 80 90 100
QRRLPAKKSR QQLQREKALV EQSQKLGLQD GSTSLLPEQL LSAPKQRVNV
110 120 130 140 150
QKPPFSSPTL PSHFTLTSPV GDGQPQGIES QPKELGLENS HDGHNNVEIL
160 170 180 190 200
PPKPDCKLEK KKVELQEKSR WEVLQQEQRL MEEKNKRKKA LLAKAIAERS
210 220 230 240 250
KRTQAETMKL KRIQKELQAL DDMVSADIGI LRNRIDQASL DYSYARKRFD
260 270 280 290 300
RAEAEYIAAK LDIQRKTEIK EQLTEHLCTI IQQNELRKAK KLEELMQQLD
310 320 330 340 350
VEADEETLEL EVEVERLLHE QEVESRRPVV RLERPFQPAE ESVTLEFAKE
360 370 380 390
NRKCQEQAVS PKVDDQCGNS SSIPFLSPNC PNQEGNDISA ALAT
Length:394
Mass (Da):44,993
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i056A2F7386D3B372
GO
Isoform 2 (identifier: Q5T7V8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     247-394: Missing.

Show »
Length:246
Mass (Da):27,992
Checksum:i19FAA47220C97C44
GO
Isoform 3 (identifier: Q5T7V8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-207: Missing.

Show »
Length:187
Mass (Da):21,540
Checksum:iEA62D736AA030AAA
GO
Isoform 4 (identifier: Q5T7V8-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-180: Missing.

Show »
Length:214
Mass (Da):24,652
Checksum:iCEB00CBCE486A00D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
R4GMT2R4GMT2_HUMAN
RAB6-interacting golgin
GORAB
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti228I → T in BAB13903 (PubMed:14702039).Curated1
Sequence conflicti293E → G in AAH47476 (PubMed:15489334).Curated1
Sequence conflicti316R → G in BAB13903 (PubMed:14702039).Curated1
Sequence conflicti379N → D in AAD32702 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027867320E → K1 PublicationCorresponds to variant dbSNP:rs913257EnsemblClinVar.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0209761 – 207Missing in isoform 3. 1 PublicationAdd BLAST207
Alternative sequenceiVSP_0209771 – 180Missing in isoform 4. 1 PublicationAdd BLAST180
Alternative sequenceiVSP_020978247 – 394Missing in isoform 2. 1 PublicationAdd BLAST148

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF143889 mRNA Translation: AAD32702.1
AK021814 mRNA Translation: BAB13903.1
AL162399 Genomic DNA No translation available.
BC047476 mRNA Translation: AAH47476.1
BC064945 mRNA Translation: AAH64945.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1289.1 [Q5T7V8-1]
CCDS53428.1 [Q5T7V8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001139511.1, NM_001146039.1 [Q5T7V8-2]
NP_001307181.1, NM_001320252.1 [Q5T7V8-4]
NP_689494.2, NM_152281.2 [Q5T7V8-1]
XP_006711691.1, XM_006711628.3 [Q5T7V8-4]
XP_011508452.1, XM_011510150.2 [Q5T7V8-4]
XP_011508453.1, XM_011510151.1 [Q5T7V8-4]
XP_016858296.1, XM_017002807.1 [Q5T7V8-4]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.183702

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367762; ENSP00000356736; ENSG00000120370 [Q5T7V8-2]
ENST00000367763; ENSP00000356737; ENSG00000120370 [Q5T7V8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92344

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92344

UCSC genome browser

More...
UCSCi
uc001ggz.5 human [Q5T7V8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF143889 mRNA Translation: AAD32702.1
AK021814 mRNA Translation: BAB13903.1
AL162399 Genomic DNA No translation available.
BC047476 mRNA Translation: AAH47476.1
BC064945 mRNA Translation: AAH64945.1
CCDSiCCDS1289.1 [Q5T7V8-1]
CCDS53428.1 [Q5T7V8-2]
RefSeqiNP_001139511.1, NM_001146039.1 [Q5T7V8-2]
NP_001307181.1, NM_001320252.1 [Q5T7V8-4]
NP_689494.2, NM_152281.2 [Q5T7V8-1]
XP_006711691.1, XM_006711628.3 [Q5T7V8-4]
XP_011508452.1, XM_011510150.2 [Q5T7V8-4]
XP_011508453.1, XM_011510151.1 [Q5T7V8-4]
XP_016858296.1, XM_017002807.1 [Q5T7V8-4]
UniGeneiHs.183702

3D structure databases

ProteinModelPortaliQ5T7V8
SMRiQ5T7V8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124937, 20 interactors
IntActiQ5T7V8, 59 interactors
MINTiQ5T7V8
STRINGi9606.ENSP00000356737

PTM databases

iPTMnetiQ5T7V8
PhosphoSitePlusiQ5T7V8

Polymorphism and mutation databases

BioMutaiGORAB
DMDMi74745442

Proteomic databases

EPDiQ5T7V8
jPOSTiQ5T7V8
MaxQBiQ5T7V8
PaxDbiQ5T7V8
PeptideAtlasiQ5T7V8
PRIDEiQ5T7V8
ProteomicsDBi64687
64688 [Q5T7V8-2]
64689 [Q5T7V8-3]
64690 [Q5T7V8-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367762; ENSP00000356736; ENSG00000120370 [Q5T7V8-2]
ENST00000367763; ENSP00000356737; ENSG00000120370 [Q5T7V8-1]
GeneIDi92344
KEGGihsa:92344
UCSCiuc001ggz.5 human [Q5T7V8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92344
DisGeNETi92344
EuPathDBiHostDB:ENSG00000120370.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GORAB
HGNCiHGNC:25676 GORAB
HPAiHPA027208
HPA027250
MalaCardsiGORAB
MIMi231070 phenotype
607983 gene
neXtProtiNX_Q5T7V8
OpenTargetsiENSG00000120370
Orphaneti2078 Geroderma osteodysplastica
PharmGKBiPA164720285

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IJC7 Eukaryota
ENOG4111VTM LUCA
GeneTreeiENSGT00390000014886
HOGENOMiHOG000112758
InParanoidiQ5T7V8
KOiK19748
OMAiMKLKRIQ
OrthoDBi1277705at2759
PhylomeDBiQ5T7V8
TreeFamiTF324839

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
GORAB human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
92344

Protein Ontology

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PROi
PR:Q5T7V8

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000120370 Expressed in 189 organ(s), highest expression level in testis
CleanExiHS_SCYL1BP1
ExpressionAtlasiQ5T7V8 baseline and differential
GenevisibleiQ5T7V8 HS

Family and domain databases

InterProiView protein in InterPro
IPR007033 GORAB
PANTHERiPTHR21470 PTHR21470, 1 hit
PfamiView protein in Pfam
PF04949 Transcrip_act, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGORAB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T7V8
Secondary accession number(s): Q49A22
, Q6P1P9, Q9HAE6, Q9Y350
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: December 21, 2004
Last modified: January 16, 2019
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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