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UniProtKB - Q5T7N2 (LITD1_HUMAN)

Protein

LINE-1 type transposase domain-containing protein 1

Gene

L1TD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • single-stranded RNA binding Source: GO_Central
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LINE-1 type transposase domain-containing protein 1
Alternative name(s):
ES cell-associated protein 11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:L1TD1
Synonyms:ECAT11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000240563.1

Human Gene Nomenclature Database

More...HGNCi		HGNC:25595 L1TD1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5T7N2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		54596

Open Targets

More...OpenTargetsi		ENSG00000240563

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA145008170

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		L1TD1

Domain mapping of disease mutations (DMDM)

More...DMDMi		74745406

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003072172 – 865LINE-1 type transposase domain-containing protein 1Add BLAST864

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei2PhosphoserineCombined sources1
Modified residuei149PhosphothreonineCombined sources1
Modified residuei154PhosphoserineCombined sources1
Modified residuei472PhosphoserineCombined sources1
Modified residuei476PhosphoserineCombined sources1
Modified residuei478PhosphoserineCombined sources1
Modified residuei518PhosphoserineCombined sources1
Modified residuei561PhosphoserineCombined sources1
Modified residuei573PhosphoserineCombined sources1
Modified residuei640PhosphoserineCombined sources1
Modified residuei648PhosphoserineCombined sources1
Modified residuei665PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5T7N2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5T7N2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5T7N2

PeptideAtlas

More...PeptideAtlasi		Q5T7N2

PRoteomics IDEntifications database

More...PRIDEi		Q5T7N2

ProteomicsDB human proteome resource

More...ProteomicsDBi		64668

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5T7N2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5T7N2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000240563 Expressed in 73 organ(s), highest expression level in amniotic fluid

CleanEx database of gene expression profiles

More...CleanExi		HS_L1TD1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5T7N2 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		120072, 20 interactors

Protein interaction database and analysis system

More...IntActi		Q5T7N2, 18 interactors

Molecular INTeraction database

More...MINTi		Q5T7N2

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000419901

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1865
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2LR6NMR-A/B235-321[»]
3SOOX-ray2.73A/B/C235-321[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		Q5T7N2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5T7N2

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q5T7N2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili642 – 684Sequence analysisAdd BLAST43

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi369 – 488Glu-richAdd BLAST120
Compositional biasi534 – 537Poly-Glu4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the transposase 22 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410J6GY Eukaryota
ENOG410YV4T LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153334

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000113335

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG094915

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5T7N2

Identification of Orthologs from Complete Genome Data

More...OMAi		FEPKFLC

Database of Orthologous Groups

More...OrthoDBi		455018at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5T7N2

TreeFam database of animal gene trees

More...TreeFami		TF351152

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR035300 L1_dsRBD
IPR004244 Transposase_22

The PANTHER Classification System

More...PANTHERi		PTHR11505 PTHR11505, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF17490 Tnp_22_dsRBD, 2 hits
PF02994 Transposase_22, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q5T7N2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDVSTSVQS KFARLAKKKE NITYMKREQL TETDKDIAPV LDLKCKDVSA 
        60         70         80         90        100
IMNKFKVLME IQDLMFEEMR ETLKNDLKAV LGGKATIPEV KNSENSSSRT 
       110        120        130        140        150
EFQQIINLAL QKTGMVGKIE GENSKIGDDN ENLTFKLEVN ELSGKLDNTN 
       160        170        180        190        200
EYNSNDGKKL PQGESRSYEV MGSMEETLCN IDDRDGNRNV HLEFTERESR 
       210        220        230        240        250
KDGEDEFVKE MREERKFQKL KNKEEVLKAS REEKVLMDEG AVLTLVADLS 
       260        270        280        290        300
SATLDISKQW SNVFNILREN DFEPKFLCEV KLAFKCDGEI KTFSDLQSLR 
       310        320        330        340        350
KFASQKSSVK ELLKDVLPQK EEINQGGRKY GIQEKRDKTL IDSKHRAGEI 
       360        370        380        390        400
TSDGLSFLFL KEVKVAKPEE MKNLETQEEE FSELEELDEE ASGMEDDEDT 
       410        420        430        440        450
SGLEEEEEEP SGLEEEEEEE ASGLEEDEAS GLEEEEEQTS EQDSTFQGHT 
       460        470        480        490        500
LVDAKHEVEI TSDGMETTFI DSVEDSESEE EEEGKSSETG KVKTTSLTEK 
       510        520        530        540        550
KASRRQKEIP FSYLVGDSGK KKLVKHQVVH KTQEEEETAV PTSQGTGTPC 
       560        570        580        590        600
LTLCLASPSK SLEMSHDEHK KHSHTNLSIS TGVTKLKKTE EKKHRTLHTE 
       610        620        630        640        650
ELTSKEADLT EETEENLRSS VINSIREIKE EIGNLKSSHS GVLEIENSVD 
       660        670        680        690        700
DLSSRMDILE ERIDSLEDQI EEFSKDTMQM TKQIISKERQ RDIEERSRSC 
       710        720        730        740        750
NIRLIGIPEK ESYENRAEDI IKEIIDENFA ELKKGSSLEI VSACRVPSKI 
       760        770        780        790        800
DEKRLTPRHI LVKFWNSSDK EKIIRASRER REITYQGTRI RLTADLSLDT 
       810        820        830        840        850
LDARSKWSNV FKVLLEKGFN PRILYPAKMA FDFRGKTKVF LSIEEFRDYV 
       860 
LHMPTLRELL GNNIP
Length:865
Mass (Da):98,850
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC7E33893A1E675CC
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA91878 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAA91878 differs from that shown. Reason: Erroneous termination at position 555. Translated as Leu.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti548T → I in BAA92011 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03537727R → S. Corresponds to variant dbSNP:rs7552335Ensembl.1
Natural variantiVAR_035378246V → A4 PublicationsCorresponds to variant dbSNP:rs7542665Ensembl.1
Natural variantiVAR_035379309V → M4 PublicationsCorresponds to variant dbSNP:rs7533274Ensembl.1
Natural variantiVAR_035380329K → N3 PublicationsCorresponds to variant dbSNP:rs2457828Ensembl.1
Natural variantiVAR_035381549P → T. Corresponds to variant dbSNP:rs11207933Ensembl.1
Natural variantiVAR_035382613T → I. Corresponds to variant dbSNP:rs2886644Ensembl.1
Natural variantiVAR_051094860L → V. Corresponds to variant dbSNP:rs11207934Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB211065 mRNA Translation: BAD95492.1
AK001746 mRNA Translation: BAA91878.1 Sequence problems.
AK001973 mRNA Translation: BAA92011.1
AL834314 mRNA Translation: CAD38984.1
AL162739 Genomic DNA No translation available.
BC111559 mRNA Translation: AAI11560.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS619.1

NCBI Reference Sequences

More...RefSeqi		NP_001158307.1, NM_001164835.1
NP_061952.3, NM_019079.4

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.685462

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000498273; ENSP00000419901; ENSG00000240563

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54596

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54596

UCSC genome browser

More...UCSCi		uc001dae.6 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB211065 mRNA Translation: BAD95492.1
AK001746 mRNA Translation: BAA91878.1 Sequence problems.
AK001973 mRNA Translation: BAA92011.1
AL834314 mRNA Translation: CAD38984.1
AL162739 Genomic DNA No translation available.
BC111559 mRNA Translation: AAI11560.1
CCDSiCCDS619.1
RefSeqiNP_001158307.1, NM_001164835.1
NP_061952.3, NM_019079.4
UniGeneiHs.685462

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2LR6NMR-A/B235-321[»]
3SOOX-ray2.73A/B/C235-321[»]
ProteinModelPortaliQ5T7N2
SMRiQ5T7N2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120072, 20 interactors
IntActiQ5T7N2, 18 interactors
MINTiQ5T7N2
STRINGi9606.ENSP00000419901

PTM databases

iPTMnetiQ5T7N2
PhosphoSitePlusiQ5T7N2

Polymorphism and mutation databases

BioMutaiL1TD1
DMDMi74745406

Proteomic databases

EPDiQ5T7N2
jPOSTiQ5T7N2
PaxDbiQ5T7N2
PeptideAtlasiQ5T7N2
PRIDEiQ5T7N2
ProteomicsDBi64668

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000498273; ENSP00000419901; ENSG00000240563
GeneIDi54596
KEGGihsa:54596
UCSCiuc001dae.6 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54596
DisGeNETi54596
EuPathDBiHostDB:ENSG00000240563.1

GeneCards: human genes, protein and diseases

More...GeneCardsi		L1TD1

H-Invitational Database, human transcriptome db

More...H-InvDBi		HIX0000653
HGNCiHGNC:25595 L1TD1
neXtProtiNX_Q5T7N2
OpenTargetsiENSG00000240563
PharmGKBiPA145008170

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410J6GY Eukaryota
ENOG410YV4T LUCA
GeneTreeiENSGT00940000153334
HOGENOMiHOG000113335
HOVERGENiHBG094915
InParanoidiQ5T7N2
OMAiFEPKFLC
OrthoDBi455018at2759
PhylomeDBiQ5T7N2
TreeFamiTF351152

Miscellaneous databases

EvolutionaryTraceiQ5T7N2

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		L1TD1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54596

Protein Ontology

More...PROi		PR:Q5T7N2

Gene expression databases

BgeeiENSG00000240563 Expressed in 73 organ(s), highest expression level in amniotic fluid
CleanExiHS_L1TD1
GenevisibleiQ5T7N2 HS

Family and domain databases

InterProiView protein in InterPro
IPR035300 L1_dsRBD
IPR004244 Transposase_22
PANTHERiPTHR11505 PTHR11505, 2 hits
PfamiView protein in Pfam
PF17490 Tnp_22_dsRBD, 2 hits
PF02994 Transposase_22, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLITD1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T7N2
Secondary accession number(s): Q8NDA1, Q9NUV8, Q9NV78
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: December 21, 2004
Last modified: January 16, 2019
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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