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UniProtKB - Q5T700 (LRAD1_HUMAN)

Entry version 120 (26 Feb 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Low-density lipoprotein receptor class A domain-containing protein 1

Gene

LDLRAD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Low-density lipoprotein receptor class A domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LDLRAD1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:32069 LDLRAD1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5T700

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei43 – 63HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		388633

Open Targets

More...OpenTargetsi		ENSG00000203985

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671554

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5T700 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LDLRAD1

Domain mapping of disease mutations (DMDM)

More...DMDMi		74745299

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002993761 – 205Low-density lipoprotein receptor class A domain-containing protein 1Add BLAST205

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi72 ↔ 89PROSITE-ProRule annotation
Disulfide bondi83 ↔ 102PROSITE-ProRule annotation
Disulfide bondi96 ↔ 113PROSITE-ProRule annotation
Disulfide bondi141 ↔ 160PROSITE-ProRule annotation
Disulfide bondi163 ↔ 180PROSITE-ProRule annotation
Disulfide bondi170 ↔ 193PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Lipoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5T700

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5T700

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5T700

PeptideAtlas

More...PeptideAtlasi		Q5T700

PRoteomics IDEntifications database

More...PRIDEi		Q5T700

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		64626 [Q5T700-1]
64627 [Q5T700-2]
64628 [Q5T700-3]
7255

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000203985 Expressed in right uterine tube and 37 other tissues

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA052489

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		132783, 16 interactors

Protein interaction database and analysis system

More...IntActi		Q5T700, 34 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000360411

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5T700 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini71 – 114LDL-receptor class A 1PROSITE-ProRule annotationAdd BLAST44
Domaini115 – 161LDL-receptor class A 2; atypicalPROSITE-ProRule annotationAdd BLAST47
Domaini162 – 203LDL-receptor class A 3; atypicalPROSITE-ProRule annotationAdd BLAST42

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the LDLR family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IXG1 Eukaryota
ENOG410YIDU LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000008557

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_115457_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5T700

Identification of Orthologs from Complete Genome Data

More...OMAi		VTACPPC

Database of Orthologous Groups

More...OrthoDBi		1360842at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5T700

TreeFam database of animal gene trees

More...TreeFami		TF343451

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		4.10.400.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036055 LDL_receptor-like_sf
IPR002172 LDrepeatLR_classA_rpt
IPR040093 LRAD1

The PANTHER Classification System

More...PANTHERi		PTHR22722:SF5 PTHR22722:SF5, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00057 Ldl_recept_a, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00261 LDLRECEPTOR

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00192 LDLa, 3 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57424 SSF57424, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01209 LDLRA_1, 1 hit
PS50068 LDLRA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q5T700-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNKVFPQGEN GYTAAESKAH PGGEAGGGHL CCSRRGACLS ASLLLLLATV 
        60         70         80         90        100
AALIALVTIL GLPSCTPGAQ ACITLTNRTG FLCHDQRSCI PASGVCDGVR 
       110        120        130        140        150
TCTHGEDEDE SLCRDVPQSL PHFLVAHCGD PASWIYSDQK CDGTNNCGDC 
       160        170        180        190        200
SDELSPVTVC PPCGPGWWRC PSTFFKYCDC IPRHLCRDHV QHCSDWSDEY 

ACPGP
Length:205
Mass (Da):21,834
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49CF4F64F9EC6C9A
GO
Isoform 2 (identifier: Q5T700-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-66: MNKVFPQGEN...VTILGLPSCT → MQGTRAELSAHSPSRAAGNRRHEQGLP

Show »
Length:166
Mass (Da):18,166
Checksum:i6580B3D296EC7BB6
GO
Isoform 3 (identifier: Q5T700-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     25-114: AGGGHLCCSR...GEDEDESLCR → G

Show »
Length:116
Mass (Da):12,721
Checksum:i2EC3AED3E5BDFC90
GO
Isoform 4 (identifier: Q5T700-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     25-67: Missing.

Show »
Length:162
Mass (Da):17,674
Checksum:iABC08174AA5ABF6F
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0276171 – 66MNKVF…LPSCT → MQGTRAELSAHSPSRAAGNR RHEQGLP in isoform 2. 1 PublicationAdd BLAST66
Alternative sequenceiVSP_02761825 – 114AGGGH…ESLCR → G in isoform 3. 1 PublicationAdd BLAST90
Alternative sequenceiVSP_05453225 – 67Missing in isoform 4. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL353898 Genomic DNA No translation available.
BC103740 mRNA No translation available.
BC127708 mRNA Translation: AAI27709.1
BC127709 mRNA Translation: AAI27710.1
BC140760 mRNA Translation: AAI40761.1
BC144466 mRNA Translation: AAI44467.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS30725.1 [Q5T700-1]
CCDS60145.1 [Q5T700-3]
CCDS60146.1 [Q5T700-4]
CCDS60147.1 [Q5T700-2]

NCBI Reference Sequences

More...RefSeqi		NP_001010978.2, NM_001010978.3 [Q5T700-1]
NP_001263321.1, NM_001276392.1 [Q5T700-2]
NP_001263322.1, NM_001276393.1 [Q5T700-4]
NP_001263323.1, NM_001276394.1 [Q5T700-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000371362; ENSP00000360413; ENSG00000203985 [Q5T700-3]
ENST00000371360; ENSP00000360411; ENSG00000203985 [Q5T700-1]
ENST00000420619; ENSP00000411017; ENSG00000203985 [Q5T700-2]
ENST00000545928; ENSP00000445871; ENSG00000203985 [Q5T700-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		388633

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:388633

UCSC genome browser

More...UCSCi		uc001cwm.3 human [Q5T700-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL353898 Genomic DNA No translation available.
BC103740 mRNA No translation available.
BC127708 mRNA Translation: AAI27709.1
BC127709 mRNA Translation: AAI27710.1
BC140760 mRNA Translation: AAI40761.1
BC144466 mRNA Translation: AAI44467.1
CCDSiCCDS30725.1 [Q5T700-1]
CCDS60145.1 [Q5T700-3]
CCDS60146.1 [Q5T700-4]
CCDS60147.1 [Q5T700-2]
RefSeqiNP_001010978.2, NM_001010978.3 [Q5T700-1]
NP_001263321.1, NM_001276392.1 [Q5T700-2]
NP_001263322.1, NM_001276393.1 [Q5T700-4]
NP_001263323.1, NM_001276394.1 [Q5T700-3]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi132783, 16 interactors
IntActiQ5T700, 34 interactors
STRINGi9606.ENSP00000360411

Polymorphism and mutation databases

BioMutaiLDLRAD1
DMDMi74745299

Proteomic databases

jPOSTiQ5T700
MassIVEiQ5T700
PaxDbiQ5T700
PeptideAtlasiQ5T700
PRIDEiQ5T700
ProteomicsDBi64626 [Q5T700-1]
64627 [Q5T700-2]
64628 [Q5T700-3]
7255

Genome annotation databases

EnsembliENST00000371362; ENSP00000360413; ENSG00000203985 [Q5T700-3]
ENST00000371360; ENSP00000360411; ENSG00000203985 [Q5T700-1]
ENST00000420619; ENSP00000411017; ENSG00000203985 [Q5T700-2]
ENST00000545928; ENSP00000445871; ENSG00000203985 [Q5T700-4]
GeneIDi388633
KEGGihsa:388633
UCSCiuc001cwm.3 human [Q5T700-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		388633
DisGeNETi388633

GeneCards: human genes, protein and diseases

More...GeneCardsi		LDLRAD1
HGNCiHGNC:32069 LDLRAD1
HPAiHPA052489
neXtProtiNX_Q5T700
OpenTargetsiENSG00000203985
PharmGKBiPA142671554

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IXG1 Eukaryota
ENOG410YIDU LUCA
GeneTreeiENSGT00390000008557
HOGENOMiCLU_115457_0_0_1
InParanoidiQ5T700
OMAiVTACPPC
OrthoDBi1360842at2759
PhylomeDBiQ5T700
TreeFamiTF343451

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		388633
PharosiQ5T700 Tdark

Protein Ontology

More...PROi		PR:Q5T700
RNActiQ5T700 protein

Gene expression databases

BgeeiENSG00000203985 Expressed in right uterine tube and 37 other tissues

Family and domain databases

Gene3Di4.10.400.10, 2 hits
InterProiView protein in InterPro
IPR036055 LDL_receptor-like_sf
IPR002172 LDrepeatLR_classA_rpt
IPR040093 LRAD1
PANTHERiPTHR22722:SF5 PTHR22722:SF5, 1 hit
PfamiView protein in Pfam
PF00057 Ldl_recept_a, 1 hit
PRINTSiPR00261 LDLRECEPTOR
SMARTiView protein in SMART
SM00192 LDLa, 3 hits
SUPFAMiSSF57424 SSF57424, 2 hits
PROSITEiView protein in PROSITE
PS01209 LDLRA_1, 1 hit
PS50068 LDLRA_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLRAD1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T700
Secondary accession number(s): A0PJY0, B7ZME3, Q5T6Z9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: December 21, 2004
Last modified: February 26, 2020
This is version 120 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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