Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 122 (11 Dec 2019)
Sequence version 1 (21 Dec 2004)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Probable gluconokinase

Gene

IDNK

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: D-gluconate degradation

This protein is involved in the pathway D-gluconate degradation, which is part of Carbohydrate acid metabolism.
View all proteins of this organism that are known to be involved in the pathway D-gluconate degradation and in Carbohydrate acid metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi11 – 18ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:HS14230-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00792

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable gluconokinase (EC:2.7.1.12)
Alternative name(s):
Gluconate kinase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IDNK
Synonyms:C9orf103
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000148057.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:31367 IDNK

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611343 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5T6J7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000148057

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134880846

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5T6J7 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IDNK

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74745228

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003273701 – 187Probable gluconokinaseAdd BLAST187

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5T6J7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5T6J7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5T6J7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5T6J7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5T6J7

PeptideAtlas

More...
PeptideAtlasi
Q5T6J7

PRoteomics IDEntifications database

More...
PRIDEi
Q5T6J7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
64588 [Q5T6J7-1]
64589 [Q5T6J7-2]
64590 [Q5T6J7-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5T6J7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5T6J7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000148057 Expressed in 195 organ(s), highest expression level in kidney epithelium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5T6J7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5T6J7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA020378
HPA058429

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000365601

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5T6J7 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5T6J7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the gluconokinase GntK/GntV family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3354 Eukaryota
COG3265 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003364

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000032567

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5T6J7

KEGG Orthology (KO)

More...
KOi
K00851

Identification of Orthologs from Complete Genome Data

More...
OMAi
ENFIQVS

Database of Orthologous Groups

More...
OrthoDBi
1275465at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5T6J7

TreeFam database of animal gene trees

More...
TreeFami
TF315136

Family and domain databases

Conserved Domains Database

More...
CDDi
cd02021 GntK, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase
IPR031322 Shikimate/glucono_kinase
IPR006001 Therm_gnt_kin

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01202 SKI, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01313 therm_gnt_kin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T6J7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAPGALLVM GVSGSGKSTV GALLASELGW KFYDADDYHP EENRRKMGKG
60 70 80 90 100
IPLNDQDRIP WLCNLHDILL RDVASGQRVV LACSALKKTY RDILTQGKDG
110 120 130 140 150
VALKCEESGK EAKQAEMQLL VVHLSGSFEV ISGRLLKREG HFMPPELLQS
160 170 180
QFETLEPPAA PENFIQISVD KNVSEIIATI METLKMK
Length:187
Mass (Da):20,578
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3E95DDC781422BF5
GO
Isoform 2 (identifier: Q5T6J7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: MAAPGALLVMGVSGSGK → MKKPRPAAAA...PEQAAAGPRR

Show »
Length:230
Mass (Da):25,297
Checksum:iF14D598D616EA58B
GO
Isoform 3 (identifier: Q5T6J7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-46: Missing.

Show »
Length:141
Mass (Da):15,699
Checksum:i4CD5B0CFCD0047C3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T6J8Q5T6J8_HUMAN
Probable gluconokinase
IDNK
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W7J0F8W7J0_HUMAN
Probable gluconokinase
IDNK
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PP74E9PP74_HUMAN
Probable gluconokinase
IDNK
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PP88E9PP88_HUMAN
Probable gluconokinase
IDNK
106Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_042433185K → T. Corresponds to variant dbSNP:rs1052690Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0327351 – 46Missing in isoform 3. CuratedAdd BLAST46
Alternative sequenceiVSP_0327361 – 17MAAPG…SGSGK → MKKPRPAAAAPSPRPPACSR GAHPGTASELRVPALRRGGC GDRRLREEAAPEQAAAGPRR in isoform 2. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY615889 mRNA Translation: AAT27441.1
AL354920 Genomic DNA No translation available.
CH471089 Genomic DNA Translation: EAW62654.1
CH471089 Genomic DNA Translation: EAW62657.1
BC142991 mRNA Translation: AAI42992.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35048.2 [Q5T6J7-1]
CCDS59134.1 [Q5T6J7-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001001551.2, NM_001001551.3 [Q5T6J7-1]
NP_001243844.1, NM_001256915.1 [Q5T6J7-3]
XP_006717173.1, XM_006717110.3 [Q5T6J7-2]
XP_016870213.1, XM_017014724.1 [Q5T6J7-3]
XP_016870214.1, XM_017014725.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000376419; ENSP00000365601; ENSG00000148057 [Q5T6J7-1]
ENST00000454393; ENSP00000403290; ENSG00000148057 [Q5T6J7-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
414328

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:414328

UCSC genome browser

More...
UCSCi
uc004amu.4 human [Q5T6J7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY615889 mRNA Translation: AAT27441.1
AL354920 Genomic DNA No translation available.
CH471089 Genomic DNA Translation: EAW62654.1
CH471089 Genomic DNA Translation: EAW62657.1
BC142991 mRNA Translation: AAI42992.1
CCDSiCCDS35048.2 [Q5T6J7-1]
CCDS59134.1 [Q5T6J7-3]
RefSeqiNP_001001551.2, NM_001001551.3 [Q5T6J7-1]
NP_001243844.1, NM_001256915.1 [Q5T6J7-3]
XP_006717173.1, XM_006717110.3 [Q5T6J7-2]
XP_016870213.1, XM_017014724.1 [Q5T6J7-3]
XP_016870214.1, XM_017014725.1

3D structure databases

SMRiQ5T6J7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000365601

PTM databases

iPTMnetiQ5T6J7
PhosphoSitePlusiQ5T6J7

Polymorphism and mutation databases

BioMutaiIDNK
DMDMi74745228

Proteomic databases

EPDiQ5T6J7
jPOSTiQ5T6J7
MassIVEiQ5T6J7
MaxQBiQ5T6J7
PaxDbiQ5T6J7
PeptideAtlasiQ5T6J7
PRIDEiQ5T6J7
ProteomicsDBi64588 [Q5T6J7-1]
64589 [Q5T6J7-2]
64590 [Q5T6J7-3]

Genome annotation databases

EnsembliENST00000376419; ENSP00000365601; ENSG00000148057 [Q5T6J7-1]
ENST00000454393; ENSP00000403290; ENSG00000148057 [Q5T6J7-3]
GeneIDi414328
KEGGihsa:414328
UCSCiuc004amu.4 human [Q5T6J7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
414328
EuPathDBiHostDB:ENSG00000148057.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IDNK
HGNCiHGNC:31367 IDNK
HPAiHPA020378
HPA058429
MIMi611343 gene
neXtProtiNX_Q5T6J7
OpenTargetsiENSG00000148057
PharmGKBiPA134880846

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3354 Eukaryota
COG3265 LUCA
GeneTreeiENSGT00390000003364
HOGENOMiHOG000032567
InParanoidiQ5T6J7
KOiK00851
OMAiENFIQVS
OrthoDBi1275465at2759
PhylomeDBiQ5T6J7
TreeFamiTF315136

Enzyme and pathway databases

UniPathwayiUPA00792
BioCyciMetaCyc:HS14230-MONOMER

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
IDNK human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
414328
PharosiQ5T6J7 Tbio

Protein Ontology

More...
PROi
PR:Q5T6J7
RNActiQ5T6J7 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000148057 Expressed in 195 organ(s), highest expression level in kidney epithelium
ExpressionAtlasiQ5T6J7 baseline and differential
GenevisibleiQ5T6J7 HS

Family and domain databases

CDDicd02021 GntK, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR031322 Shikimate/glucono_kinase
IPR006001 Therm_gnt_kin
PfamiView protein in Pfam
PF01202 SKI, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR01313 therm_gnt_kin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGNTK_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T6J7
Secondary accession number(s): A5PLN6, Q5T6J6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: December 21, 2004
Last modified: December 11, 2019
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again