UniProtKB - Q5T6F7 (Q5T6F7_HUMAN)
Protein
Submitted name:
Steroidogenic factor 1
Gene
NR5A1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- nuclear receptor activity Source: InterPro
Keywordsi
Molecular function | ReceptorARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Steroidogenic factor 1Imported |
Gene namesi | Name:NR5A1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7983, NR5A1 |
VEuPathDBi | HostDB:ENSG00000136931.9 |
Subcellular locationi
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000136931, Expressed in right adrenal gland cortex and 75 other tissues |
ExpressionAtlasi | Q5T6F7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 20 – 243 | NR LBDInterPro annotationAdd BLAST | 224 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000153391 |
HOGENOMi | CLU_007368_11_4_1 |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit |
InterProi | View protein in InterPro IPR035500, NHR-like_dom_sf IPR016355, NR5_fam IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001723, Nuclear_hrmn_rcpt |
PANTHERi | PTHR24086, PTHR24086, 1 hit |
Pfami | View protein in Pfam PF00104, Hormone_recep, 1 hit |
PRINTSi | PR00398, STRDHORMONER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q5T6F7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
VEEEGDVSNR GVELLQLEPD EDQVRARILG CLQEPTKSRP DQPAAFGLLC
60 70 80 90 100
RMADQTFISI VDWARRCMVF KELEVADQMT LLQNCWSELL VFDHIYRQVQ
110 120 130 140 150
HGKEGSILLV TGQEVELTTV ATQAGSLLHS LVLRAQELVL QLLALQLDRQ
160 170 180 190 200
EFVCLKFIIL FSLDLKFLNN HILVKDAQEK ANAALLDYTL CHYPHCGDKF
210 220 230 240
QQLLLCLVEV RALSMQAKEY LYHKHLGNEM PRNNLLIEML QAKQT
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ13285 | STF1_HUMAN | Steroidogenic factor 1 | NR5A1 AD4BP, FTZF1, SF1 | 461 | Annotation score: | ||
F1DAM0 | F1DAM0_HUMAN | Steroidogenic factor 1 | NR5A1 | 421 | Annotation score: | ||
Q5T6F6 | Q5T6F6_HUMAN | Steroidogenic factor 1 | NR5A1 | 177 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL137846 Genomic DNA No translation available. AL354979 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000373587; ENSP00000362689; ENSG00000136931 |
UCSCi | uc064vqb.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL137846 Genomic DNA No translation available. AL354979 Genomic DNA No translation available. |
3D structure databases
SMRi | Q5T6F7 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | Q5T6F7 |
PRIDEi | Q5T6F7 |
ProteomicsDBi | 64581 |
Protocols and materials databases
Antibodypediai | 16333, 411 antibodies |
Genome annotation databases
Ensembli | ENST00000373587; ENSP00000362689; ENSG00000136931 |
UCSCi | uc064vqb.1, human |
Organism-specific databases
HGNCi | HGNC:7983, NR5A1 |
OpenTargetsi | ENSG00000136931 |
VEuPathDBi | HostDB:ENSG00000136931.9 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153391 |
HOGENOMi | CLU_007368_11_4_1 |
Gene expression databases
Bgeei | ENSG00000136931, Expressed in right adrenal gland cortex and 75 other tissues |
ExpressionAtlasi | Q5T6F7, baseline and differential |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit |
InterProi | View protein in InterPro IPR035500, NHR-like_dom_sf IPR016355, NR5_fam IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001723, Nuclear_hrmn_rcpt |
PANTHERi | PTHR24086, PTHR24086, 1 hit |
Pfami | View protein in Pfam PF00104, Hormone_recep, 1 hit |
PRINTSi | PR00398, STRDHORMONER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5T6F7_HUMAN | |
Accessioni | Q5T6F7Primary (citable) accession number: Q5T6F7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 21, 2004 |
Last sequence update: | December 21, 2004 | |
Last modified: | February 10, 2021 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |