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Entry version 95 (13 Feb 2019)
Sequence version 3 (18 May 2010)
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Protein

Coiled-coil domain-containing protein 183

Gene

CCDC183

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 183
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC183
Synonyms:KIAA1984
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000213213.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28236 CCDC183

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615955 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5T5S1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000213213

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134944889

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC183

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439313

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002934651 – 534Coiled-coil domain-containing protein 183Add BLAST534

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5T5S1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5T5S1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5T5S1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5T5S1

PeptideAtlas

More...
PeptideAtlasi
Q5T5S1

PRoteomics IDEntifications database

More...
PRIDEi
Q5T5S1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
64547
64548 [Q5T5S1-2]
64549 [Q5T5S1-3]
64550 [Q5T5S1-4]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q5T5S1

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5T5S1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5T5S1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000213213 Expressed in 89 organ(s), highest expression level in left testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5T5S1 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043812

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124391, 31 interactors

Protein interaction database and analysis system

More...
IntActi
Q5T5S1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000338013

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5T5S1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5T5S1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili10 – 54Sequence analysisAdd BLAST45
Coiled coili136 – 209Sequence analysisAdd BLAST74
Coiled coili323 – 396Sequence analysisAdd BLAST74

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi530 – 534Poly-Lys5

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410II7I Eukaryota
ENOG410YH5U LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163544

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000050237

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG058359

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5T5S1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CSHLWDI

Database of Orthologous Groups

More...
OrthoDBi
622819at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5T5S1

TreeFam database of animal gene trees

More...
TreeFami
TF324955

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T5S1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRRHSETDVE EQTQELKTIT QLQEQCRALQ IQGVKENMDQ NKATLALLRS
60 70 80 90 100
NIRRGAQDWA LAKKYDQWTI SKACGKNLPL RLAHCRSTME VVREKLRKYV
110 120 130 140 150
FDRVNMHNLL IHLVRRRGQK LESMQLELDS LRSQPDASKE ELRLLQIIRQ
160 170 180 190 200
LENNIEKTMI KIITSQNIHL LYLDLLDYLK TVLAGYPIEL DKLQNLVVNY
210 220 230 240 250
CSELSDMKIM SQDAMMITDE VKRNMRQREA SFIEERRARE NRLNQQKKLI
260 270 280 290 300
DKIHTKETSE KYRRGQMDLD FPSNLMSTET LKLRRKETST AEMEYQSGVT
310 320 330 340 350
AVVEKVKSAV RCSHVWDITS RFLAQRNTEE NLELQMEDCE EWRVQLKALV
360 370 380 390 400
KQLELEEAVL KFRQKPSSIS FKSVEKKMTD MLKEEEERLQ LAHSNMTKGQ
410 420 430 440 450
ELLLTIQMGI DNLYVRLMGI NLPATQREVV LSNTLDLNSK LAYCEGKLTY
460 470 480 490 500
LADRVQMVSR TEEGDTKVRD TLESSTLMEK YNTRISFENR EEDMIDTFQF
510 520 530
PDMDHSYVPS RAEIKRQAQR LIEGKLKAAK KKKK
Length:534
Mass (Da):62,689
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD38115A57A2E228D
GO
Isoform 2 (identifier: Q5T5S1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     427-515: REVVLSNTLD...SYVPSRAEIK → VPGVRLSCHTPGPWAGPEG

Note: No experimental confirmation available.Curated
Show »
Length:464
Mass (Da):54,204
Checksum:i20C5106AE55240DA
GO
Isoform 3 (identifier: Q5T5S1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-88: Missing.
     283-534: Missing.

Show »
Length:194
Mass (Da):23,210
Checksum:i2DCB391A47A9C853
GO
Isoform 4 (identifier: Q5T5S1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-42: Missing.
     43-90: ATLALLRSNI...RLAHCRSTME → MLRSRRGTEQ...HEWAVPFPTQ
     370-424: SFKSVEKKMT...VRLMGINLPA → RCPGLPGLRA...HLHTPELLSP
     425-534: Missing.

Note: No experimental confirmation available.
Show »
Length:383
Mass (Da):44,321
Checksum:iBB2411FDF2E327BC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E9W6G5E9W6_HUMAN
Coiled-coil domain-containing prote...
CCDC183 hCG_2039834
318Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Isoform 2 : The sequence AAH64582 differs from that shown. Reason: Frameshift at position 222.Curated
Isoform 2 : The sequence AAH64582 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB85570 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03304638M → T. Corresponds to variant dbSNP:rs945386Ensembl.1
Natural variantiVAR_033047113L → R. Corresponds to variant dbSNP:rs4546744Ensembl.1
Natural variantiVAR_033048129D → A. Corresponds to variant dbSNP:rs7859194Ensembl.1
Natural variantiVAR_033049342W → R3 PublicationsCorresponds to variant dbSNP:rs2811795Ensembl.1
Natural variantiVAR_063112421N → T2 PublicationsCorresponds to variant dbSNP:rs2254143Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0264771 – 88Missing in isoform 3. 1 PublicationAdd BLAST88
Alternative sequenceiVSP_0264781 – 42Missing in isoform 4. 1 PublicationAdd BLAST42
Alternative sequenceiVSP_02647943 – 90ATLAL…RSTME → MLRSRRGTEQVPSPRFPVGL PRASTRPPAGGLHGGPLRNH EWAVPFPTQ in isoform 4. 1 PublicationAdd BLAST48
Alternative sequenceiVSP_026481283 – 534Missing in isoform 3. 1 PublicationAdd BLAST252
Alternative sequenceiVSP_026483370 – 424SFKSV…INLPA → RCPGLPGLRATHPSLTKAPG CSQAGSWEYTHCQQACVSHR GARGLHLHTPELLSP in isoform 4. 1 PublicationAdd BLAST55
Alternative sequenceiVSP_026484425 – 534Missing in isoform 4. 1 PublicationAdd BLAST110
Alternative sequenceiVSP_026482427 – 515REVVL…RAEIK → VPGVRLSCHTPGPWAGPEG in isoform 2. 1 PublicationAdd BLAST89

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB075864 mRNA Translation: BAB85570.1 Different initiation.
AK092639 mRNA Translation: BAC03931.1
AL355987 Genomic DNA No translation available.
BC064582 mRNA Translation: AAH64582.1 Sequence problems.
BC137317 mRNA Translation: AAI37318.1
BC137318 mRNA Translation: AAI37319.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43906.1 [Q5T5S1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001034463.4, NM_001039374.4 [Q5T5S1-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.728796

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000338005; ENSP00000338013; ENSG00000213213 [Q5T5S1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84960

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84960

UCSC genome browser

More...
UCSCi
uc004cjf.4 human [Q5T5S1-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB075864 mRNA Translation: BAB85570.1 Different initiation.
AK092639 mRNA Translation: BAC03931.1
AL355987 Genomic DNA No translation available.
BC064582 mRNA Translation: AAH64582.1 Sequence problems.
BC137317 mRNA Translation: AAI37318.1
BC137318 mRNA Translation: AAI37319.1
CCDSiCCDS43906.1 [Q5T5S1-1]
RefSeqiNP_001034463.4, NM_001039374.4 [Q5T5S1-1]
UniGeneiHs.728796

3D structure databases

ProteinModelPortaliQ5T5S1
SMRiQ5T5S1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124391, 31 interactors
IntActiQ5T5S1, 1 interactor
STRINGi9606.ENSP00000338013

PTM databases

CarbonylDBiQ5T5S1
iPTMnetiQ5T5S1
PhosphoSitePlusiQ5T5S1

Polymorphism and mutation databases

BioMutaiCCDC183
DMDMi296439313

Proteomic databases

EPDiQ5T5S1
jPOSTiQ5T5S1
MaxQBiQ5T5S1
PaxDbiQ5T5S1
PeptideAtlasiQ5T5S1
PRIDEiQ5T5S1
ProteomicsDBi64547
64548 [Q5T5S1-2]
64549 [Q5T5S1-3]
64550 [Q5T5S1-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000338005; ENSP00000338013; ENSG00000213213 [Q5T5S1-1]
GeneIDi84960
KEGGihsa:84960
UCSCiuc004cjf.4 human [Q5T5S1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84960
EuPathDBiHostDB:ENSG00000213213.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC183
HGNCiHGNC:28236 CCDC183
HPAiHPA043812
MIMi615955 gene
neXtProtiNX_Q5T5S1
OpenTargetsiENSG00000213213
PharmGKBiPA134944889

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410II7I Eukaryota
ENOG410YH5U LUCA
GeneTreeiENSGT00940000163544
HOGENOMiHOG000050237
HOVERGENiHBG058359
InParanoidiQ5T5S1
OMAiCSHLWDI
OrthoDBi622819at2759
PhylomeDBiQ5T5S1
TreeFamiTF324955

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCDC183 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84960

Protein Ontology

More...
PROi
PR:Q5T5S1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000213213 Expressed in 89 organ(s), highest expression level in left testis
ExpressionAtlasiQ5T5S1 baseline and differential

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCC183_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T5S1
Secondary accession number(s): B2RP89
, C9JD38, Q6P2D9, Q8NAI4, Q8TF18
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 18, 2010
Last modified: February 13, 2019
This is version 95 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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