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UniProtKB - Q5T457 (Q5T457_HUMAN)
Protein
Submitted name:
Ankyrin repeat domain-containing protein 2
Gene
ANKRD2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Ankyrin repeat domain-containing protein 2 |
Gene namesi | Name:ANKRD2 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:495, ANKRD2 |
VEuPathDBi | HostDB:ENSG00000165887 |
PTM / Processingi
Proteomic databases
MaxQBi | Q5T457 |
PeptideAtlasi | Q5T457 |
PRIDEi | Q5T457 |
ProteomicsDBi | 64435 |
Expressioni
Gene expression databases
Bgeei | ENSG00000165887, Expressed in deltoid and 155 other tissues |
ExpressionAtlasi | Q5T457, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 153 – 185 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 186 – 218 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 219 – 251 | ANKPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 99 – 120 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 270 – 300 | DisorderedSequence analysisAdd BLAST | 31 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000153956 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 4 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q5T457-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDGTMEDSEA VQRATALIEQ RLAQEEENEK LRGDARQKLP MDLLVLEDEK
60 70 80 90 100
HHGAQSAALQ KVKGQERVRK TSLDLRREII DVGGIQNLIE LRKKRKQKKR
110 120 130 140 150
DALAASHEPP PEPEEITGPV DEETFLKAAV EGKMKVIEKF LADGGSADTC
160 170 180 190 200
DQFRRTALHR ASLEGHMEIL EKLLDNGATV DFQDRLDCTA MHWACRGGHL
210 220 230 240 250
EVVKLLQSHG ADTNVRDKEG DTALHDAVRL NRYKIIKLLL LHGADMMTKN
260 270 280 290 300
LAGKTPTDLV QLWQADTRHA LEHPEPGAEH NGLEGPNDSG RETPQPVPAQ
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9GZV1 | ANKR2_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD2 ARPP | 360 | Annotation score: | ||
A0A0A0MRN9 | A0A0A0MRN9_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD2 | 333 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355315 Genomic DNA No translation available. AL359388 Genomic DNA No translation available. |
RefSeqi | NP_001278148.2, NM_001291219.2 NP_001333726.1, NM_001346797.1 |
Genome annotation databases
Ensembli | ENST00000455090.1; ENSP00000403114.1; ENSG00000165887.12 |
GeneIDi | 26287 |
UCSCi | uc057vga.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355315 Genomic DNA No translation available. AL359388 Genomic DNA No translation available. |
RefSeqi | NP_001278148.2, NM_001291219.2 NP_001333726.1, NM_001346797.1 |
3D structure databases
SMRi | Q5T457 |
ModBasei | Search... |
Proteomic databases
MaxQBi | Q5T457 |
PeptideAtlasi | Q5T457 |
PRIDEi | Q5T457 |
ProteomicsDBi | 64435 |
Protocols and materials databases
Antibodypediai | 30973, 91 antibodies from 23 providers |
DNASUi | 26287 |
Genome annotation databases
Ensembli | ENST00000455090.1; ENSP00000403114.1; ENSG00000165887.12 |
GeneIDi | 26287 |
UCSCi | uc057vga.1, human |
Organism-specific databases
CTDi | 26287 |
HGNCi | HGNC:495, ANKRD2 |
OpenTargetsi | ENSG00000165887 |
VEuPathDBi | HostDB:ENSG00000165887 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153956 |
Miscellaneous databases
BioGRID-ORCSi | 26287, 5 hits in 1032 CRISPR screens |
GenomeRNAii | 26287 |
Gene expression databases
Bgeei | ENSG00000165887, Expressed in deltoid and 155 other tissues |
ExpressionAtlasi | Q5T457, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 4 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5T457_HUMAN | |
Accessioni | Q5T457Primary (citable) accession number: Q5T457 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 21, 2004 |
Last sequence update: | December 21, 2004 | |
Last modified: | May 25, 2022 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |