UniProtKB - Q5T3U5 (MRP7_HUMAN)
Protein
ATP-binding cassette sub-family C member 10
Gene
ABCC10
Organism
Homo sapiens (Human)
Status
Functioni
ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4) (PubMed:12527806, PubMed:15256465). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel (PubMed:15256465, PubMed:23087055). Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP (PubMed:12527806).3 Publications
Catalytic activityi
- an S-substituted glutathione(in) + ATP + H2O = ADP + an S-substituted glutathione(out) + H+ + phosphate1 PublicationEC:7.6.2.31 PublicationThis reaction proceeds in the forward1 Publication direction.
- 17β-estradiol 17-O-(β-D-glucuronate)(in) + ATP + H2O = 17β-estradiol 17-O-(β-D-glucuronate)(out) + ADP + H+ + phosphate2 PublicationsThis reaction proceeds in the forward1 Publication direction.
- This reaction proceeds in the forwardCurated direction.
- ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2).2 Publications EC:7.6.2.2
Kineticsi
- KM=0.057 mM for leukotriene C41 Publication
- KM=3.3 mM for ATP1 Publication
- KM=57.8 µM for 17-beta-estradiol 17-(beta-D-glucuronide) (at 37 degrees Celsius)1 Publication
- Vmax=20 pmol/min/mg enzyme toward 17-beta-estradiol 17-(beta-D-glucuronide) (at 37 degrees Celsius)1 Publication
pH dependencei
Optimum pH is 7.5.1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 633 – 640 | ATP 1PROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 1280 – 1287 | ATP 2PROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATPase-coupled transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- transmembrane transport Source: GO_Central
Keywordsi
Molecular function | Translocase |
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
PathwayCommonsi | Q5T3U5 |
Reactomei | R-HSA-382556, ABC-family proteins mediated transport |
SABIO-RKi | Q5T3U5 |
Protein family/group databases
TCDBi | 3.A.1.208.31, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ABCC10 Synonyms:MRP7, SIMRP7 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:52, ABCC10 |
MIMi | 612509, gene |
neXtProti | NX_Q5T3U5 |
VEuPathDBi | HostDB:ENSG00000124574.14 |
Subcellular locationi
Plasma membrane
- Cell membrane 2 Publications; Multi-pass membrane protein PROSITE-ProRule annotation2 Publications
- Basolateral cell membrane 1 Publication; Multi-pass membrane protein Sequence analysis
Lysosome
- lysosomal membrane Source: UniProtKB
Plasma Membrane
- plasma membrane Source: ARUK-UCL
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 32 – 52 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 70 – 90 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 102 – 122 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 133 – 153 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 172 – 192 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 293 – 313 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 320 – 340 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 391 – 411 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 414 – 434 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 507 – 527 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 538 – 558 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 875 – 895 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 933 – 953 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 974 – 994 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 1051 – 1071 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 1153 – 1173 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 1182 – 1202 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 89845 |
OpenTargetsi | ENSG00000124574 |
PharmGKBi | PA24392 |
Miscellaneous databases
Pharosi | Q5T3U5, Tbio |
Chemistry databases
ChEMBLi | CHEMBL2073687 |
DrugBanki | DB00091, Cyclosporine DB00987, Cytarabine DB00694, Daunorubicin DB01248, Docetaxel DB00997, Doxorubicin DB00783, Estradiol DB13952, Estradiol acetate DB13953, Estradiol benzoate DB13954, Estradiol cypionate DB13955, Estradiol dienanthate DB13956, Estradiol valerate DB00773, Etoposide DB00441, Gemcitabine DB00563, Methotrexate DB01229, Paclitaxel DB00203, Sildenafil DB04348, Taurocholic acid DB00300, Tenofovir disoproxil DB00661, Verapamil DB00541, Vincristine |
DrugCentrali | Q5T3U5 |
Genetic variation databases
BioMutai | ABCC10 |
DMDMi | 74756298 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000253576 | 1 – 1492 | ATP-binding cassette sub-family C member 10Add BLAST | 1492 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 463 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 467 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | Q5T3U5 |
MassIVEi | Q5T3U5 |
MaxQBi | Q5T3U5 |
PaxDbi | Q5T3U5 |
PeptideAtlasi | Q5T3U5 |
PRIDEi | Q5T3U5 |
ProteomicsDBi | 64416 [Q5T3U5-1] 64417 [Q5T3U5-2] |
PTM databases
iPTMneti | Q5T3U5 |
PhosphoSitePlusi | Q5T3U5 |
Expressioni
Tissue specificityi
Specifically expressed in spleen.1 Publication
Widely expressed.1 Publication
Gene expression databases
Bgeei | ENSG00000124574, Expressed in right hemisphere of cerebellum and 230 other tissues |
ExpressionAtlasi | Q5T3U5, baseline and differential |
Genevisiblei | Q5T3U5, HS |
Organism-specific databases
HPAi | ENSG00000124574, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 124617, 14 interactors |
IntActi | Q5T3U5, 9 interactors |
STRINGi | 9606.ENSP00000361608 |
Miscellaneous databases
RNActi | Q5T3U5, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 285 – 563 | ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST | 279 | |
Domaini | 598 – 824 | ABC transporter 1PROSITE-ProRule annotationAdd BLAST | 227 | |
Domaini | 885 – 1210 | ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST | 326 | |
Domaini | 1246 – 1479 | ABC transporter 2PROSITE-ProRule annotationAdd BLAST | 234 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0054, Eukaryota |
GeneTreei | ENSGT00940000161082 |
HOGENOMi | CLU_000604_27_1_1 |
InParanoidi | Q5T3U5 |
OMAi | PPYAWPS |
OrthoDBi | 138195at2759 |
PhylomeDBi | Q5T3U5 |
TreeFami | TF105203 |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q5T3U5-1) [UniParc]FASTAAdd to basket
Also known as: Mrp7
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MERLLAQLCG SSAAWPLPLW EGDTTGHCFT QLVLSALPHA LLAVLSACYL
60 70 80 90 100
GTPRSPDYIL PCSPGWRLRL AASFLLSVFP LLDLLPVALP PGAGPGPIGL
110 120 130 140 150
EVLAGCVAAV AWISHSLALW VLAHSPHGHS RGPLALALVA LLPAPALVLT
160 170 180 190 200
VLWHCQRGTL LPPLLPGPMA RLCLLILQLA ALLAYALGWA APGGPREPWA
210 220 230 240 250
QEPLLPEDQE PEVAEDGESW LSRFSYAWLA PLLARGACGE LRQPQDICRL
260 270 280 290 300
PHRLQPTYLA RVFQAHWQEG ARLWRALYGA FGRCYLALGL LKLVGTMLGF
310 320 330 340 350
SGPLLLSLLV GFLEEGQEPL SHGLLYALGL AGGAVLGAVL QNQYGYEVYK
360 370 380 390 400
VTLQARGAVL NILYCKALQL GPSRPPTGEA LNLLGTDSER LLNFAGSFHE
410 420 430 440 450
AWGLPLQLAI TLYLLYQQVG VAFVGGLILA LLLVPVNKVI ATRIMASNQE
460 470 480 490 500
MLQHKDARVK LVTELLSGIR VIKFCGWEQA LGARVEACRA RELGRLRVIK
510 520 530 540 550
YLDAACVYLW AALPVVISIV IFITYVLMGH QLTATKVFTA LALVRMLILP
560 570 580 590 600
LNNFPWVING LLEAKVSLDR IQLFLDLPNH NPQAYYSPDP PAEPSTVLEL
610 620 630 640 650
HGALFSWDPV GTSLETFISH LEVKKGMLVG IVGKVGCGKS SLLAAIAGEL
660 670 680 690 700
HRLRGHVAVR GLSKGFGLAT QEPWIQFATI RDNILFGKTF DAQLYKEVLE
710 720 730 740 750
ACALNDDLSI LPAGDQTEVG EKGVTLSGGQ RARIALARAV YQEKELYLLD
760 770 780 790 800
DPLAAVDADV ANHLLHRCIL GMLSYTTRLL CTHRTEYLER ADAVLLMEAG
810 820 830 840 850
RLIRAGPPSE ILPLVQAVPK AWAENGQESD SATAQSVQNP EKTKEGLEEE
860 870 880 890 900
QSTSGRLLQE ESKKEGAVAL HVYQAYWKAV GQGLALAILF SLLLMQATRN
910 920 930 940 950
AADWWLSHWI SQLKAENSSQ EAQPSTSPAS MGLFSPQLLL FSPGNLYIPV
960 970 980 990 1000
FPLPKAAPNG SSDIRFYLTV YATIAGVNSL CTLLRAVLFA AGTLQAAATL
1010 1020 1030 1040 1050
HRRLLHRVLM APVTFFNATP TGRILNRFSS DVACADDSLP FILNILLANA
1060 1070 1080 1090 1100
AGLLGLLAVL GSGLPWLLLL LPPLSIMYYH VQRHYRASSR ELRRLGSLTL
1110 1120 1130 1140 1150
SPLYSHLADT LAGLSVLRAT GATYRFEEEN LRLLELNQRC QFATSATMQW
1160 1170 1180 1190 1200
LDIRLQLMGA AVVSAIAGIA LVQHQQGLAN PGLVGLSLSY ALSLTGLLSG
1210 1220 1230 1240 1250
LVSSFTQTEA MLVSVERLEE YTCDLPQEPQ GQPLQLGTGW LTQGGVEFQD
1260 1270 1280 1290 1300
VVLAYRPGLP NALDGVTFCV QPGEKLGIVG RTGSGKSSLL LVLFRLLEPS
1310 1320 1330 1340 1350
SGRVLLDGVD TSQLELAQLR SQLAIIPQEP FLFSGTVREN LDPQGLHKDR
1360 1370 1380 1390 1400
ALWQALKQCH LSEVITSMGG LDGELGEGGR SLSLGQRQLL CLARALLTDA
1410 1420 1430 1440 1450
KILCIDEATA SVDQKTDQLL QQTICKRFAN KTVLTIAHRL NTILNSDRVL
1460 1470 1480 1490
VLQAGRVVEL DSPATLRNQP HSLFQQLLQS SQQGVPASLG GP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketD6R9B3 | D6R9B3_HUMAN | Multidrug resistance-associated pro... | ABCC10 | 277 | Annotation score: | ||
H0Y904 | H0Y904_HUMAN | Multidrug resistance-associated pro... | ABCC10 | 129 | Annotation score: |
Sequence cautioni
The sequence BAA92227 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 208 | D → E in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 220 | Missing in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 631 | I → T in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 764 | L → P in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 809 | S → P in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 888 | I → T in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 1030 | S → F in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 1134 | L → F in BAB15736 (PubMed:11214971).Curated | 1 | |
Sequence conflicti | 1276 | L → V in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 1455 | G → E in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 1481 | S → C in AAK39642 (PubMed:12566991).Curated | 1 | |
Sequence conflicti | 1490 | G → R in AAK39642 (PubMed:12566991).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_028391 | 948 | I → T. Corresponds to variant dbSNP:rs2125739Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_021078 | 1 – 43 | Missing in isoform 2. 1 PublicationAdd BLAST | 43 | |
Alternative sequenceiVSP_021079 | 44 – 52 | VLSACYLGT → MCLLVFPLV in isoform 2. 1 Publication | 9 | |
Alternative sequenceiVSP_021080 | 588 | P → PDCGRLGAQIKWLLCS in isoform 2. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY032599 mRNA Translation: AAK39642.1 AK000002 mRNA Translation: BAA92227.1 Different initiation. AK024446 mRNA Translation: BAB15736.1 Sequence problems. AL359813 Genomic DNA No translation available. AL133613 mRNA Translation: CAB63742.1 |
CCDSi | CCDS4896.1 [Q5T3U5-2] CCDS56430.1 [Q5T3U5-1] |
PIRi | T43469 |
RefSeqi | NP_001185863.1, NM_001198934.1 [Q5T3U5-1] NP_258261.2, NM_033450.2 [Q5T3U5-2] |
Genome annotation databases
Ensembli | ENST00000244533; ENSP00000244533; ENSG00000124574 [Q5T3U5-2] ENST00000372530; ENSP00000361608; ENSG00000124574 [Q5T3U5-1] |
GeneIDi | 89845 |
KEGGi | hsa:89845 |
UCSCi | uc003ouy.2, human [Q5T3U5-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
ABCMdb Database for mutations in ABC proteins |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY032599 mRNA Translation: AAK39642.1 AK000002 mRNA Translation: BAA92227.1 Different initiation. AK024446 mRNA Translation: BAB15736.1 Sequence problems. AL359813 Genomic DNA No translation available. AL133613 mRNA Translation: CAB63742.1 |
CCDSi | CCDS4896.1 [Q5T3U5-2] CCDS56430.1 [Q5T3U5-1] |
PIRi | T43469 |
RefSeqi | NP_001185863.1, NM_001198934.1 [Q5T3U5-1] NP_258261.2, NM_033450.2 [Q5T3U5-2] |
3D structure databases
SMRi | Q5T3U5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 124617, 14 interactors |
IntActi | Q5T3U5, 9 interactors |
STRINGi | 9606.ENSP00000361608 |
Chemistry databases
ChEMBLi | CHEMBL2073687 |
DrugBanki | DB00091, Cyclosporine DB00987, Cytarabine DB00694, Daunorubicin DB01248, Docetaxel DB00997, Doxorubicin DB00783, Estradiol DB13952, Estradiol acetate DB13953, Estradiol benzoate DB13954, Estradiol cypionate DB13955, Estradiol dienanthate DB13956, Estradiol valerate DB00773, Etoposide DB00441, Gemcitabine DB00563, Methotrexate DB01229, Paclitaxel DB00203, Sildenafil DB04348, Taurocholic acid DB00300, Tenofovir disoproxil DB00661, Verapamil DB00541, Vincristine |
DrugCentrali | Q5T3U5 |
Protein family/group databases
TCDBi | 3.A.1.208.31, the atp-binding cassette (abc) superfamily |
PTM databases
iPTMneti | Q5T3U5 |
PhosphoSitePlusi | Q5T3U5 |
Genetic variation databases
BioMutai | ABCC10 |
DMDMi | 74756298 |
Proteomic databases
jPOSTi | Q5T3U5 |
MassIVEi | Q5T3U5 |
MaxQBi | Q5T3U5 |
PaxDbi | Q5T3U5 |
PeptideAtlasi | Q5T3U5 |
PRIDEi | Q5T3U5 |
ProteomicsDBi | 64416 [Q5T3U5-1] 64417 [Q5T3U5-2] |
Protocols and materials databases
Antibodypediai | 30398, 266 antibodies |
DNASUi | 89845 |
Genome annotation databases
Ensembli | ENST00000244533; ENSP00000244533; ENSG00000124574 [Q5T3U5-2] ENST00000372530; ENSP00000361608; ENSG00000124574 [Q5T3U5-1] |
GeneIDi | 89845 |
KEGGi | hsa:89845 |
UCSCi | uc003ouy.2, human [Q5T3U5-1] |
Organism-specific databases
CTDi | 89845 |
DisGeNETi | 89845 |
GeneCardsi | ABCC10 |
HGNCi | HGNC:52, ABCC10 |
HPAi | ENSG00000124574, Low tissue specificity |
MIMi | 612509, gene |
neXtProti | NX_Q5T3U5 |
OpenTargetsi | ENSG00000124574 |
PharmGKBi | PA24392 |
VEuPathDBi | HostDB:ENSG00000124574.14 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0054, Eukaryota |
GeneTreei | ENSGT00940000161082 |
HOGENOMi | CLU_000604_27_1_1 |
InParanoidi | Q5T3U5 |
OMAi | PPYAWPS |
OrthoDBi | 138195at2759 |
PhylomeDBi | Q5T3U5 |
TreeFami | TF105203 |
Enzyme and pathway databases
PathwayCommonsi | Q5T3U5 |
Reactomei | R-HSA-382556, ABC-family proteins mediated transport |
SABIO-RKi | Q5T3U5 |
Miscellaneous databases
BioGRID-ORCSi | 89845, 0 hits in 869 CRISPR screens |
ChiTaRSi | ABCC10, human |
GeneWikii | ABCC10 |
GenomeRNAii | 89845 |
Pharosi | Q5T3U5, Tbio |
PROi | PR:Q5T3U5 |
RNActi | Q5T3U5, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000124574, Expressed in right hemisphere of cerebellum and 230 other tissues |
ExpressionAtlasi | Q5T3U5, baseline and differential |
Genevisiblei | Q5T3U5, HS |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MRP7_HUMAN | |
Accessioni | Q5T3U5Primary (citable) accession number: Q5T3U5 Secondary accession number(s): Q8NHX7 Q9UF48 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 17, 2006 |
Last sequence update: | December 21, 2004 | |
Last modified: | February 10, 2021 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families