PDSS1

Functionⁱ

Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.1 Publication

Catalytic activityⁱ

(2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.1 Publication

Cofactorⁱ

Mg²⁺By similarityNote: Binds 3 Mg²⁺ ions per subunit.By similarity

Pathwayⁱ: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	134	Isopentenyl diphosphateBy similarity	1
Binding siteⁱ	137	Isopentenyl diphosphateBy similarity	1
Binding siteⁱ	173	Isopentenyl diphosphateBy similarity	1
Metal bindingⁱ	180	Magnesium 1By similarity	1
Metal bindingⁱ	180	Magnesium 2By similarity	1
Metal bindingⁱ	184	Magnesium 1By similarity	1
Metal bindingⁱ	184	Magnesium 2By similarity	1
Binding siteⁱ	189	Polyprenyl diphosphateBy similarity	1
Binding siteⁱ	190	Isopentenyl diphosphateBy similarity	1
Binding siteⁱ	266	Polyprenyl diphosphateBy similarity	1
Binding siteⁱ	267	Polyprenyl diphosphateBy similarity	1
Binding siteⁱ	304	Polyprenyl diphosphateBy similarity	1
Metal bindingⁱ	307	Magnesium 3By similarity	1
Binding siteⁱ	321	Polyprenyl diphosphateBy similarity	1

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW
protein heterodimerization activity
Source: HGNC
Inferred from direct assayⁱ
- 16262699
trans-hexaprenyltranstransferase activity Source: Ensembl
trans-octaprenyltranstransferase activity Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

isoprenoid biosynthetic process
Source: HGNC
Inferred from direct assayⁱ
- 16262699
protein heterotetramerization Source: Ensembl
ubiquinone biosynthetic process
Source: HGNC
Inferred from direct assayⁱ
- 16262699

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Transferase
Biological process	Isoprene biosynthesis, Ubiquinone biosynthesis
Ligand	Magnesium, Metal-binding

Enzyme and pathway databases

BioCycⁱ	MetaCyc:HS07530-MONOMER
BRENDAⁱ	2.5.1.91 2681
Reactomeⁱ	R-HSA-2142789 Ubiquinol biosynthesis
UniPathwayⁱ	UPA00232

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Decaprenyl-diphosphate synthase subunit 1 (EC:2.5.1.91) Alternative name(s): All-trans-decaprenyl-diphosphate synthase subunit 1 Decaprenyl pyrophosphate synthase subunit 1 Trans-prenyltransferase 1 Short name: TPT 1
Gene namesⁱ	Name:PDSS1 Synonyms:DPS1, TPRT
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 10

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000148459.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:17759 PDSS1
MIMⁱ	607429 gene
neXtProtⁱ	NX_Q5T2R2

Keywords - Cellular componentⁱ

Mitochondrion

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Coenzyme Q10 deficiency, primary, 2 (COQ10D2)1 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionAn autosomal recessive multisystem disorder characterized by early-onset deafness, optic atrophy, mild mental retardation, peripheral neuropathy, obesity, livedo reticularis, and cardiac valvulopathy.

Keywords - Diseaseⁱ

Disease mutation, Primary mitochondrial disease

Organism-specific databases

DisGeNET More...DisGeNETⁱ	23590
MalaCards human disease database More...MalaCardsⁱ	PDSS1
MIMⁱ	614651 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000148459
Orphanetⁱ	254898 Deafness - encephaloneuropathy - obesity - valvulopathy
PharmGKBⁱ	PA134982512

Polymorphism and mutation databases

BioMutaⁱ	PDSS1
DMDMⁱ	74744657

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000123975	1 – 415	Decaprenyl-diphosphate synthase subunit 1Add BLAST		415

Proteomic databases

EPDⁱ	Q5T2R2
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q5T2R2
PaxDbⁱ	Q5T2R2
PeptideAtlas More...PeptideAtlasⁱ	Q5T2R2
PRIDEⁱ	Q5T2R2
ProteomicsDBⁱ	64353 64354 [Q5T2R2-2] 64355 [Q5T2R2-3]

PTM databases

iPTMnetⁱ	Q5T2R2
PhosphoSitePlusⁱ	Q5T2R2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000148459
CleanExⁱ	HS_PDSS1
ExpressionAtlasⁱ	Q5T2R2 baseline and differential
Genevisibleⁱ	Q5T2R2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA038032 HPA042741

HPAⁱ

HPA038032
HPA042741

Interactionⁱ

Subunit structureⁱ

Heterotetramer of 2 DPS1/TPRT and 2 DLP1 subunits.1 Publication

GO - Molecular functionⁱ

protein heterodimerization activity
Source: HGNC
Inferred from direct assayⁱ
- 16262699

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	117125, 11 interactors
IntActⁱ	Q5T2R2, 2 interactors
Molecular INTeraction database More...MINTⁱ	Q5T2R2
STRINGⁱ	9606.ENSP00000365388

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5T2R2
SMRⁱ	Q5T2R2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the FPP/GGPP synthase family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0776 Eukaryota COG0142 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063378
HOGENOMⁱ	HOG000009104
HOVERGENⁱ	HBG054389
InParanoidⁱ	Q5T2R2
KEGG Orthology (KO) More...KOⁱ	K12504
OMAⁱ	GKQMRPM
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G1BWC
PhylomeDBⁱ	Q5T2R2
TreeFamⁱ	TF313548

Family and domain databases

Gene3Dⁱ	1.10.600.10, 1 hit
InterProⁱ	View protein in InterPro IPR008949 Isoprenoid_synthase_dom_sf IPR000092 Polyprenyl_synt IPR033749 Polyprenyl_synt_CS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00348 polyprenyl_synt, 1 hit
SUPFAMⁱ	SSF48576 SSF48576, 1 hit
PROSITEⁱ	View protein in PROSITE PS00723 POLYPRENYL_SYNTHASE_1, 1 hit PS00444 POLYPRENYL_SYNTHASE_2, 1 hit

Sequences (3)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: Q5T2R2-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASRWWRWRR GCSWKPAARS PGPGSPGRAG PLGPSAAAEV RAQVHRRKGL 
        60         70         80         90        100
DLSQIPYINL VKHLTSACPN VCRISRFHHT TPDSKTHSGE KYTDPFKLGW 
       110        120        130        140        150
RDLKGLYEDI RKELLISTSE LKEMSEYYFD GKGKAFRPII VALMARACNI 
       160        170        180        190        200
HHNNSRHVQA SQRAIALIAE MIHTASLVHD DVIDDASSRR GKHTVNKIWG 
       210        220        230        240        250
EKKAVLAGDL ILSAASIALA RIGNTTVISI LTQVIEDLVR GEFLQLGSKE 
       260        270        280        290        300
NENERFAHYL EKTFKKTASL IANSCKAVSV LGCPDPVVHE IAYQYGKNVG 
       310        320        330        340        350
IAFQLIDDVL DFTSCSDQMG KPTSADLKLG LATGPVLFAC QQFPEMNAMI 
       360        370        380        390        400
MRRFSLPGDV DRARQYVLQS DGVQQTTYLA QQYCHEAIRE ISKLRPSPER 
       410 
DALIQLSEIV LTRDK

Length:415

Mass (Da):46,261

Last modified:December 21, 2004 - v1

Checksum:ⁱF0B073C75CBD06D2

GO

Isoform 2 (identifier: Q5T2R2-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
279-415: SVLGCPDPVV...LSEIVLTRDK → FPRNECYDHATVQFAWRCRQSSTVCTTE

« Hide

        10         20         30         40         50
MASRWWRWRR GCSWKPAARS PGPGSPGRAG PLGPSAAAEV RAQVHRRKGL 
        60         70         80         90        100
DLSQIPYINL VKHLTSACPN VCRISRFHHT TPDSKTHSGE KYTDPFKLGW 
       110        120        130        140        150
RDLKGLYEDI RKELLISTSE LKEMSEYYFD GKGKAFRPII VALMARACNI 
       160        170        180        190        200
HHNNSRHVQA SQRAIALIAE MIHTASLVHD DVIDDASSRR GKHTVNKIWG 
       210        220        230        240        250
EKKAVLAGDL ILSAASIALA RIGNTTVISI LTQVIEDLVR GEFLQLGSKE 
       260        270        280        290        300
NENERFAHYL EKTFKKTASL IANSCKAVFP RNECYDHATV QFAWRCRQSS 

TVCTTE

Note: No experimental confirmation available.

Show »

Length:306

Mass (Da):34,304

Checksum:ⁱD5195700E8AFF902

GO

Isoform 3 (identifier: Q5T2R2-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-42: MASRWWRWRRGCSWKPAARSPGPGSPGRAGPLGPSAAAEVRA → MPA

« Hide

        10         20         30         40         50
MPAQVHRRKG LDLSQIPYIN LVKHLTSACP NVCRISRFHH TTPDSKTHSG 
        60         70         80         90        100
EKYTDPFKLG WRDLKGLYED IRKELLISTS ELKEMSEYYF DGKGKAFRPI 
       110        120        130        140        150
IVALMARACN IHHNNSRHVQ ASQRAIALIA EMIHTASLVH DDVIDDASSR 
       160        170        180        190        200
RGKHTVNKIW GEKKAVLAGD LILSAASIAL ARIGNTTVIS ILTQVIEDLV 
       210        220        230        240        250
RGEFLQLGSK ENENERFAHY LEKTFKKTAS LIANSCKAVS VLGCPDPVVH 
       260        270        280        290        300
EIAYQYGKNV GIAFQLIDDV LDFTSCSDQM GKPTSADLKL GLATGPVLFA 
       310        320        330        340        350
CQQFPEMNAM IMRRFSLPGD VDRARQYVLQ SDGVQQTTYL AQQYCHEAIR 
       360        370 
EISKLRPSPE RDALIQLSEI VLTRDK

Show »

Length:376

Mass (Da):42,089

Checksum:ⁱBB32C9961B92ED00

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	30	G → V in AAH63635 (PubMed:15489334).Curated	1
Sequence conflictⁱ	44	V → A in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	47	R → Q in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	58	I → F in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	66	S → P in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	72 – 73	CR → YS in AAD28559 (PubMed:10972372).Curated	2
Sequence conflictⁱ	76	R → Q in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	83	D → Y in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	109	D → G in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	114	L → P in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	119	S → T in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	124	M → I in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	131	G → V in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	142	A → V in AAD28559 (PubMed:10972372).Curated	1
Sequence conflictⁱ	186	A → V in BAD97134 (Ref. 3) Curated	1
Sequence conflictⁱ	298	N → D in BAD97134 (Ref. 3) Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_034879	308	D → E in COQ10D2. 1 PublicationCorresponds to variant dbSNP:rs119463988EnsemblClinVar.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_017100	1 – 42	MASRW…AEVRA → MPA in isoform 3. 1 PublicationAdd BLAST		42
Alternative sequenceⁱVSP_017101	279 – 415	SVLGC…LTRDK → FPRNECYDHATVQFAWRCRQ SSTVCTTE in isoform 2. 1 PublicationAdd BLAST		137

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF118395 mRNA Translation: AAD28559.1 AB210838 mRNA Translation: BAE48216.1 AK223414 mRNA Translation: BAD97134.1 AL390961 Genomic DNA No translation available. BC049211 mRNA Translation: AAH49211.1 BC063635 mRNA Translation: AAH63635.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS31168.1 [Q5T2R2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001308907.1, NM_001321978.1 [Q5T2R2-2] NP_055132.2, NM_014317.4 [Q5T2R2-1]
UniGeneⁱ	Hs.558468

Genome annotation databases

Ensemblⁱ	ENST00000376215; ENSP00000365388; ENSG00000148459 [Q5T2R2-1]
GeneIDⁱ	23590
KEGGⁱ	hsa:23590
UCSC genome browser More...UCSCⁱ	uc001isv.4 human [Q5T2R2-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
Q5T2R2	UPI0000D4ABB6		HUMAN		292
UPI00033437FC		CONCR		422
UPI0004419670		LIPVE		420
UPI0002C62456		southern white rhinoceros		419
Decaprenyl diphosphate synthase subunit 1		PANTR		415
+56
Q5T2R2-3	UPI000904B443		PANPR		408
UPI00072E3055		ACIJB		406
Decaprenyl diphosphate synthase subunit 1		SAIBB		383
UPI00057B9503		CAMDR		378
UPI0003C89CDD		CAMBA		349
+13

Protein	Similar proteins		Species	Score	Length
Q5T2R2	UPI0000D4ABB6		HUMAN		292
UPI00033437FC		CONCR		422
UPI0004419670		LIPVE		420
UPI0002C62456		southern white rhinoceros		419
Decaprenyl diphosphate synthase subunit 1		MACMU		415
+280
Q5T2R2-2	Uncharacterized protein		COLVI		309
Decaprenyl-diphosphate synthase subunit 1		TUPCH		301
UPI00052913F7		Buceros rhinoceros silvestris		280
Decaprenyl-diphosphate synthase subunit 1		MOUSE		280
UPI000576D84E		Bison bison bison		327
+1

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF118395 mRNA Translation: AAD28559.1 AB210838 mRNA Translation: BAE48216.1 AK223414 mRNA Translation: BAD97134.1 AL390961 Genomic DNA No translation available. BC049211 mRNA Translation: AAH49211.1 BC063635 mRNA Translation: AAH63635.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS31168.1 [Q5T2R2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001308907.1, NM_001321978.1 [Q5T2R2-2] NP_055132.2, NM_014317.4 [Q5T2R2-1]
UniGeneⁱ	Hs.558468

3D structure databases

ProteinModelPortalⁱ	Q5T2R2
SMRⁱ	Q5T2R2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	117125, 11 interactors
IntActⁱ	Q5T2R2, 2 interactors
Molecular INTeraction database More...MINTⁱ	Q5T2R2
STRINGⁱ	9606.ENSP00000365388

PTM databases

iPTMnetⁱ	Q5T2R2
PhosphoSitePlusⁱ	Q5T2R2

Polymorphism and mutation databases

BioMutaⁱ	PDSS1
DMDMⁱ	74744657

Proteomic databases

EPDⁱ	Q5T2R2
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q5T2R2
PaxDbⁱ	Q5T2R2
PeptideAtlas More...PeptideAtlasⁱ	Q5T2R2
PRIDEⁱ	Q5T2R2
ProteomicsDBⁱ	64353 64354 [Q5T2R2-2] 64355 [Q5T2R2-3]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000376215; ENSP00000365388; ENSG00000148459 [Q5T2R2-1]
GeneIDⁱ	23590
KEGGⁱ	hsa:23590
UCSC genome browser More...UCSCⁱ	uc001isv.4 human [Q5T2R2-1]

Organism-specific databases

CTDⁱ	23590
DisGeNET More...DisGeNETⁱ	23590
EuPathDBⁱ	HostDB:ENSG00000148459.15
GeneCardsⁱ	PDSS1
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:17759 PDSS1
Human Protein Atlas More...HPAⁱ	HPA038032 HPA042741
MalaCards human disease database More...MalaCardsⁱ	PDSS1
MIMⁱ	607429 gene 614651 phenotype
neXtProtⁱ	NX_Q5T2R2
Open Targets More...OpenTargetsⁱ	ENSG00000148459
Orphanetⁱ	254898 Deafness - encephaloneuropathy - obesity - valvulopathy
PharmGKBⁱ	PA134982512
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0776 Eukaryota COG0142 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063378
HOGENOMⁱ	HOG000009104
HOVERGENⁱ	HBG054389
InParanoidⁱ	Q5T2R2
KEGG Orthology (KO) More...KOⁱ	K12504
OMAⁱ	GKQMRPM
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G1BWC
PhylomeDBⁱ	Q5T2R2
TreeFamⁱ	TF313548

Enzyme and pathway databases

UniPathwayⁱ	UPA00232
BioCycⁱ	MetaCyc:HS07530-MONOMER
BRENDAⁱ	2.5.1.91 2681
Reactomeⁱ	R-HSA-2142789 Ubiquinol biosynthesis

Miscellaneous databases

ChiTaRSⁱ	PDSS1 human
GeneWikiⁱ	PDSS1
GenomeRNAiⁱ	23590
Protein Ontology More...PROⁱ	PR:Q5T2R2
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000148459
CleanExⁱ	HS_PDSS1
ExpressionAtlasⁱ	Q5T2R2 baseline and differential
Genevisibleⁱ	Q5T2R2 HS

Family and domain databases

Gene3Dⁱ	1.10.600.10, 1 hit
InterProⁱ	View protein in InterPro IPR008949 Isoprenoid_synthase_dom_sf IPR000092 Polyprenyl_synt IPR033749 Polyprenyl_synt_CS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00348 polyprenyl_synt, 1 hit
SUPFAMⁱ	SSF48576 SSF48576, 1 hit
PROSITEⁱ	View protein in PROSITE PS00723 POLYPRENYL_SYNTHASE_1, 1 hit PS00444 POLYPRENYL_SYNTHASE_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DPS1_HUMAN
Accessionⁱ	Q5T2R2Primary (citable) accession number: Q5T2R2 Secondary accession number(s): Q53F75 , Q6P473, Q86WQ8, Q9Y2W5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 24, 2006
	Last sequence update:	December 21, 2004
	Last modified:	June 20, 2018
	This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 10
Human chromosome 10: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PATHWAY comments
Index of metabolic and biosynthesis pathways
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5T2R2 (DPS1_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Decaprenyl-diphosphate synthase subunit 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: ubiquinone biosynthesis

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

Pathwayⁱ: ubiquinone biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ