UniProtKB - Q5T2H0 (Q5T2H0_HUMAN)
Protein
Submitted name:
Androgen-induced gene 1 protein
Gene
AIG1
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- 12-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 12-hydroxyoctadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 12-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 12-hydroxyoctadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 12-hexadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + H+ + hexadecanoateARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 12-octadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + H+ + octadecanoateARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 13-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 13-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 13-octadecanoyloxy-octadecanoate + H2O = 13-hydroxy-octadecanoate + H+ + octadecanoateARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 9-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 9-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- 9-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H+ARBA annotationThis reaction proceeds in the forwardARBA annotation direction.
- This reaction proceeds in the forwardARBA annotation direction.
- This reaction proceeds in the forwardARBA annotation direction.
Names & Taxonomyi
Protein namesi | Submitted name: Androgen-induced gene 1 proteinImported |
Gene namesi | Name:AIG1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:21607, AIG1 |
VEuPathDBi | HostDB:ENSG00000146416.16 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 23 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 71 – 97 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 109 – 129 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Proteomic databases
MaxQBi | Q5T2H0 |
PeptideAtlasi | Q5T2H0 |
PRIDEi | Q5T2H0 |
ProteomicsDBi | 64339 |
Expressioni
Gene expression databases
Bgeei | ENSG00000146416, Expressed in liver and 223 other tissues |
ExpressionAtlasi | Q5T2H0, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the AIG1 family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158696 |
HOGENOMi | CLU_073346_1_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR006838, Far-17a_AIG1 |
PANTHERi | PTHR10989, PTHR10989, 1 hit |
Pfami | View protein in Pfam PF04750, Far-17a_AIG1, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q5T2H0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLAVLAFPVG VFVVAVFWII YAYDREMIYP KLLDNFIPGW LNHGMHTTVL
60 70 80 90 100
PFILIEMRTS HHQYPSRSSG LTAICTFSVG YILWVCWVHH VTGMWVYPFL
110 120 130
EHIGPGARII FFGSTTILMN FLYLLGEVLN NYIWDTQK
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NVV5 | AIG1_HUMAN | Androgen-induced gene 1 protein | AIG1 CGI-103 | 238 | Annotation score: | ||
Q5THU2 | Q5THU2_HUMAN | Androgen-induced gene 1 protein | AIG1 | 47 | Annotation score: | ||
Q5T2H4 | Q5T2H4_HUMAN | Androgen-induced gene 1 protein | AIG1 | 192 | Annotation score: | ||
Q5T2H3 | Q5T2H3_HUMAN | Androgen-induced gene 1 protein | AIG1 | 123 | Annotation score: | ||
A0A2R8YCJ8 | A0A2R8YCJ8_HUMAN | Androgen-induced gene 1 protein | AIG1 | 231 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 138 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. KF458306 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000458219; ENSP00000407817; ENSG00000146416 |
UCSCi | uc063ryx.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. KF458306 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | Q5T2H0 |
PeptideAtlasi | Q5T2H0 |
PRIDEi | Q5T2H0 |
ProteomicsDBi | 64339 |
Protocols and materials databases
Antibodypediai | 53852, 143 antibodies |
Genome annotation databases
Ensembli | ENST00000458219; ENSP00000407817; ENSG00000146416 |
UCSCi | uc063ryx.1, human |
Organism-specific databases
HGNCi | HGNC:21607, AIG1 |
OpenTargetsi | ENSG00000146416 |
VEuPathDBi | HostDB:ENSG00000146416.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158696 |
HOGENOMi | CLU_073346_1_0_1 |
Miscellaneous databases
ChiTaRSi | AIG1, human |
Gene expression databases
Bgeei | ENSG00000146416, Expressed in liver and 223 other tissues |
ExpressionAtlasi | Q5T2H0, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006838, Far-17a_AIG1 |
PANTHERi | PTHR10989, PTHR10989, 1 hit |
Pfami | View protein in Pfam PF04750, Far-17a_AIG1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5T2H0_HUMAN | |
Accessioni | Q5T2H0Primary (citable) accession number: Q5T2H0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 21, 2004 |
Last sequence update: | December 21, 2004 | |
Last modified: | February 10, 2021 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |