UniProtKB - Q5T2H0 (Q5T2H0_HUMAN)

BLAST

>tr|Q5T2H0|Q5T2H0_HUMAN Androgen-induced gene 1 protein (Fragment) OS=Homo sapiens OX=9606 GN=AIG1 PE=1 SV=1
MLAVLAFPVGVFVVAVFWIIYAYDREMIYPKLLDNFIPGWLNHGMHTTVLPFILIEMRTS
HHQYPSRSSGLTAICTFSVGYILWVCWVHHVTGMWVYPFLEHIGPGARIIFFGSTTILMN
FLYLLGEVLNNYIWDTQK

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History
Entry version 86 (12 Sep 2018)
Sequence version 1 (21 Dec 2004)
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Protein

Submitted name:

Androgen-induced gene 1 protein

Gene

AIG1

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Androgen-induced gene 1 proteinImported
Gene namesⁱ	Name:AIG1Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 6

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000146416.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:21607 AIG1

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	6 – 23	HelicalSequence analysisAdd BLAST	18
Transmembraneⁱ	71 – 97	HelicalSequence analysisAdd BLAST	27
Transmembraneⁱ	109 – 129	HelicalSequence analysisAdd BLAST	21

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000146416

OpenTargetsⁱ

ENSG00000146416

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q5T2H0
PeptideAtlas More...PeptideAtlasⁱ	Q5T2H0
PRIDEⁱ	Q5T2H0

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000146416 Expressed in 208 organ(s), highest expression level in liver
ExpressionAtlasⁱ	Q5T2H0 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5T2H0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG3989 Eukaryota ENOG4111HQA LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000012526
HOGENOMⁱ	HOG000006895
HOVERGENⁱ	HBG050468

Family and domain databases

InterProⁱ	View protein in InterPro IPR006838 Far-17a_AIG1
PANTHERⁱ	PTHR10989 PTHR10989, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04750 Far-17a_AIG1, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show all Align All

Q5T2H0-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MLAVLAFPVG VFVVAVFWII YAYDREMIYP KLLDNFIPGW LNHGMHTTVL 
        60         70         80         90        100
PFILIEMRTS HHQYPSRSSG LTAICTFSVG YILWVCWVHH VTGMWVYPFL 
       110        120        130 
EHIGPGARII FFGSTTILMN FLYLLGEVLN NYIWDTQK

Length:138

Mass (Da):16,002

Last modified:December 21, 2004 - v1

Checksum:ⁱEC8CA2DEAA97B235

Computationally mapped potential isoform sequencesⁱ

There are 5 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q9NVV5	AIG1_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein, AIG-1	AIG1 CGI-103	245	Annotation score:
Q5THU2	Q5THU2_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	47	Annotation score:
Q5T2H4	Q5T2H4_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	192	Annotation score:
Q5T2H3	Q5T2H3_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	123	Annotation score:
A0A2R8YCJ8	A0A2R8YCJ8_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	231	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	138	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. KF458306 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL023581 Genomic DNA No translation available.
AL136116 Genomic DNA No translation available.
AL391726 Genomic DNA No translation available.
AL450335 Genomic DNA No translation available.
KF458306 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000458219; ENSP00000407817; ENSG00000146416
UCSC genome browser More...UCSCⁱ	uc063ryx.1 human

Protein	Similar proteins		Species	Score	Length	Source
Q5T2H0	Androgen-induced gene 1 protein		HUMAN		47	UniRef100_Q5THU2
AIG1 isoform 10		PANTR		47
AIG1 isoform 7		PONAB		47
Uncharacterized protein		PANPA		47
Androgen induced 1		GORGO		47
+3

Protein	Similar proteins		Species	Score	Length	Source
Q5T2H0	Androgen-induced gene 1 protein		HUMAN		47	UniRef90_Q5THU2
AIG1 isoform 10		PANTR		47
AIG1 isoform 7		PONAB		47
Uncharacterized protein		PANPA		47
Androgen induced 1		GORGO		47
+10

Protein	Similar proteins		Species	Score	Length	Source
Q5T2H0	Androgen induced 1		MONDO		311	UniRef50_F6T3Q1
Androgen-induced gene 1 protein		HUMAN		47
AIG1 isoform 10		PANTR		47
AIG1 isoform 7		PONAB		47
Uncharacterized protein		PANPA		47
+29

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. KF458306 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

3D structure databases

ProteinModelPortalⁱ	Q5T2H0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQBⁱ	Q5T2H0
PeptideAtlasⁱ	Q5T2H0
PRIDEⁱ	Q5T2H0

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000458219; ENSP00000407817; ENSG00000146416
UCSCⁱ	uc063ryx.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000146416.16
HGNCⁱ	HGNC:21607 AIG1
OpenTargetsⁱ	ENSG00000146416
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3989 Eukaryota ENOG4111HQA LUCA
GeneTreeⁱ	ENSGT00390000012526
HOGENOMⁱ	HOG000006895
HOVERGENⁱ	HBG050468

Miscellaneous databases

ChiTaRSⁱ	AIG1 human

ChiTaRSⁱ

AIG1 human

Gene expression databases

Bgeeⁱ	ENSG00000146416 Expressed in 208 organ(s), highest expression level in liver
ExpressionAtlasⁱ	Q5T2H0 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR006838 Far-17a_AIG1
PANTHERⁱ	PTHR10989 PTHR10989, 1 hit
Pfamⁱ	View protein in Pfam PF04750 Far-17a_AIG1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5T2H0_HUMAN
Accessionⁱ	Q5T2H0Primary (citable) accession number: Q5T2H0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 21, 2004
	Last sequence update:	December 21, 2004
	Last modified:	September 12, 2018
	This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

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UniRef

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Annotation systems

Supporting data

UniProtKB - Q5T2H0 (Q5T2H0_HUMAN)

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Androgen-induced gene 1 protein

AIG1

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ