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UniProtKB - Q5T2E6 (ARMD3_HUMAN)

Entry version 102 (08 May 2019)
Sequence version 1 (21 Dec 2004)
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Protein

Armadillo-like helical domain-containing protein 3

Gene

ARMH3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Armadillo-like helical domain-containing protein 3Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARMH3Imported
Synonyms:C10orf76Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25788 ARMH3

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5T2E6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei520 – 538HelicalSequence analysisAdd BLAST19

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79591

Open Targets

More...OpenTargetsi		ENSG00000120029

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134903060

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C10orf76

Domain mapping of disease mutations (DMDM)

More...DMDMi		74744614

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002845151 – 689Armadillo-like helical domain-containing protein 3Add BLAST689

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5T2E6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5T2E6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5T2E6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5T2E6

PeptideAtlas

More...PeptideAtlasi		Q5T2E6

PRoteomics IDEntifications database

More...PRIDEi		Q5T2E6

ProteomicsDB human proteome resource

More...ProteomicsDBi		64333
64334 [Q5T2E6-2]
64335 [Q5T2E6-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5T2E6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5T2E6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000120029 Expressed in 208 organ(s), highest expression level in heart left ventricle

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5T2E6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5T2E6 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA050913
HPA053580

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PI4KB.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		122733, 21 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000359050

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ARMH3 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4654 Eukaryota
ENOG410XQ3P LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000002554

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000006637

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5T2E6

Identification of Orthologs from Complete Genome Data

More...OMAi		KNNPRFW

Database of Orthologous Groups

More...OrthoDBi		1024171at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5T2E6

TreeFam database of animal gene trees

More...TreeFami		TF300220

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024 ARM-type_fold
IPR039868 ARMD3-like
IPR013636 DUF1741

The PANTHER Classification System

More...PANTHERi		PTHR13608 PTHR13608, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08427 DUF1741, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01158 DUF1741, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T2E6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAQVEKRGGL LRKSSASKKP LKEKVVLMYD EIFMTEDPSK CSPRFWEELF 
        60         70         80         90        100
LMKVNLEYLE GKLESLDGEE LMKIKDNINC LFQHCIQALG EEHPIRVVNA 
       110        120        130        140        150
LQTLCALIRG VHQKNKSTSG FDIINMLMGF DKAELCMKNL MESLDSLLCA 
       160        170        180        190        200
EGSESLKSLC LKLLLCLVTV TDNISQNTIL EYVMINSIFE AILQILSHPP 
       210        220        230        240        250
SRREHGYDAV VLLALLVNYR KYESVNPYIV KLSIVDDEAT LNGMGLVIAQ 
       260        270        280        290        300
ALSEYNRQYK DKEEEHQSGF FSALTNMVGS MFIADAHEKI SVQTNEAILL 
       310        320        330        340        350
ALYEAVHLNR NFITVLAQSH PEMGLVTTPV SPAPTTPVTP LGTTPPSSDV 
       360        370        380        390        400
ISSVELPLDA DVQTSNLLIT FLKYSSIVMQ DTKDEHRLHS GKLCLIILTC 
       410        420        430        440        450
IAEDQYANAF LHDDNMNFRV NLHRMPMRHR KKAADKNLPC RPLVCAVLDL 
       460        470        480        490        500
MVEFIVTHMM KEFPMDLYIR CIQVVHKLLC YQKKCRVRLH YTWRELWSAL 
       510        520        530        540        550
INLLKFLMSN ETVLLAKHNI FTLALMIVNL FNMFITYGDT FLPTPSSYDE 
       560        570        580        590        600
LYYEIIRMHQ SFDNLYSMVL RLSTNAGQWK EAASKVTHAL VNIRAIINHF 
       610        620        630        640        650
NPKIESYAAV NHISQLSEEQ VLEVVRANYD TLTLKLQDGL DQYERYSEQH 
       660        670        680 
KEAAFFKELV RSISTNVRRN LAFHTLSQEV LLKEFSTIS
Length:689
Mass (Da):78,710
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5C21E860F3E2BD68
GO
Isoform 2 (identifier: Q5T2E6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-424: Missing.

Show »
Length:265
Mass (Da):31,142
Checksum:i20CE6A14367BD03C
GO
Isoform 3 (identifier: Q5T2E6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-424: Missing.
     569-584: VLRLSTNAGQWKEAAS → EPSSTTLTPKLSPTLL
     585-689: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Show »
Length:160
Mass (Da):18,957
Checksum:i0E5722922841E7A7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T2E7Q5T2E7_HUMAN
Armadillo-like helical domain-conta...
ARMH3
198Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T2E8Q5T2E8_HUMAN
Armadillo-like helical domain-conta...
ARMH3
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti672A → V in BAB14447 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0245521 – 424Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST424
Alternative sequenceiVSP_024553569 – 584VLRLS…KEAAS → EPSSTTLTPKLSPTLL in isoform 3. 1 PublicationAdd BLAST16
Alternative sequenceiVSP_024554585 – 689Missing in isoform 3. 1 PublicationAdd BLAST105

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK023176 mRNA Translation: BAB14447.1
AC010789 Genomic DNA No translation available.
AL391827 Genomic DNA No translation available.
BC110511 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS41563.1 [Q5T2E6-1]

NCBI Reference Sequences

More...RefSeqi		NP_078817.2, NM_024541.2 [Q5T2E6-1]
XP_011538453.1, XM_011540151.2 [Q5T2E6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000370033; ENSP00000359050; ENSG00000120029 [Q5T2E6-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79591

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79591

UCSC genome browser

More...UCSCi		uc009xwy.2 human [Q5T2E6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023176 mRNA Translation: BAB14447.1
AC010789 Genomic DNA No translation available.
AL391827 Genomic DNA No translation available.
BC110511 mRNA No translation available.
CCDSiCCDS41563.1 [Q5T2E6-1]
RefSeqiNP_078817.2, NM_024541.2 [Q5T2E6-1]
XP_011538453.1, XM_011540151.2 [Q5T2E6-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi122733, 21 interactors
STRINGi9606.ENSP00000359050

PTM databases

iPTMnetiQ5T2E6
PhosphoSitePlusiQ5T2E6

Polymorphism and mutation databases

BioMutaiC10orf76
DMDMi74744614

Proteomic databases

EPDiQ5T2E6
jPOSTiQ5T2E6
MaxQBiQ5T2E6
PaxDbiQ5T2E6
PeptideAtlasiQ5T2E6
PRIDEiQ5T2E6
ProteomicsDBi64333
64334 [Q5T2E6-2]
64335 [Q5T2E6-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370033; ENSP00000359050; ENSG00000120029 [Q5T2E6-1]
GeneIDi79591
KEGGihsa:79591
UCSCiuc009xwy.2 human [Q5T2E6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79591
DisGeNETi79591

GeneCards: human genes, protein and diseases

More...GeneCardsi		ARMH3
HGNCiHGNC:25788 ARMH3
HPAiHPA050913
HPA053580
neXtProtiNX_Q5T2E6
OpenTargetsiENSG00000120029
PharmGKBiPA134903060

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4654 Eukaryota
ENOG410XQ3P LUCA
GeneTreeiENSGT00390000002554
HOGENOMiHOG000006637
InParanoidiQ5T2E6
OMAiKNNPRFW
OrthoDBi1024171at2759
PhylomeDBiQ5T2E6
TreeFamiTF300220

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		C10orf76 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79591

Protein Ontology

More...PROi		PR:Q5T2E6

Gene expression databases

BgeeiENSG00000120029 Expressed in 208 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiQ5T2E6 baseline and differential
GenevisibleiQ5T2E6 HS

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR039868 ARMD3-like
IPR013636 DUF1741
PANTHERiPTHR13608 PTHR13608, 1 hit
PfamiView protein in Pfam
PF08427 DUF1741, 1 hit
SMARTiView protein in SMART
SM01158 DUF1741, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARMD3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T2E6
Secondary accession number(s): Q2TB87, Q9H8Z9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 21, 2004
Last modified: May 8, 2019
This is version 102 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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