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Protein
Submitted name:

Probable ATP-dependent RNA helicase DDX59

Gene

DDX59

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Probable ATP-dependent RNA helicase DDX59Imported
Gene namesi
Name:DDX59Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000118197.13
HGNCiHGNC:25360 DDX59

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei173 – 196HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000118197

PTM / Processingi

Proteomic databases

MaxQBiQ5T1W1
PeptideAtlasiQ5T1W1
PRIDEiQ5T1W1

Expressioni

Gene expression databases

BgeeiENSG00000118197 Expressed in 214 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ5T1W1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5T1W1
SMRiQ5T1W1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 43Helicase ATP-bindingInterPro annotationAdd BLAST43
Domaini54 – 205Helicase C-terminalInterPro annotationAdd BLAST152

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00930000150967
HOGENOMiHOG000200515

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q5T1W1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
FQQQVLDILE NIPNDCQTIL VSATIPTSIE QLASQLLHNP VRIITGEKNL
60 70 80 90 100
PCANVRQIIL WVEDPAKKKK LFEILNDKKL FKPPVLVFVD CKLGADLLSE
110 120 130 140 150
AVQKITGLKS ISIHSEKSQI ERKNILKGLL EGDYEVVVST GVLGRGLDLI
160 170 180 190 200
SVRLVVNFDM PSSMDEYVHQ LNIIWVVPFS GININASLIA LLYSLLTTIN

MKFTP
Length:205
Mass (Da):22,874
Last modified:December 21, 2004 - v1
Checksum:i469A5835763E130C
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T1V6DDX59_HUMAN
Probable ATP-dependent RNA helicase...
DDX59 ZNHIT5
619Annotation score:
B7ZBU3B7ZBU3_HUMAN
Probable ATP-dependent RNA helicase...
DDX59
224Annotation score:
H0Y6Y1H0Y6Y1_HUMAN
Probable ATP-dependent RNA helicase...
DDX59
197Annotation score:
H0Y7Z8H0Y7Z8_HUMAN
Probable ATP-dependent RNA helicase...
DDX59
94Annotation score:
B7ZBU4B7ZBU4_HUMAN
Probable ATP-dependent RNA helicase...
DDX59
75Annotation score:
Q5T1V5Q5T1V5_HUMAN
Probable ATP-dependent RNA helicase...
DDX59
160Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445483 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000413408; ENSP00000394304; ENSG00000118197
UCSCiuc057ofp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445483 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5T1W1
SMRiQ5T1W1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ5T1W1
PeptideAtlasiQ5T1W1
PRIDEiQ5T1W1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413408; ENSP00000394304; ENSG00000118197
UCSCiuc057ofp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000118197.13
HGNCiHGNC:25360 DDX59
OpenTargetsiENSG00000118197
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00930000150967
HOGENOMiHOG000200515

Miscellaneous databases

ChiTaRSiDDX59 human

Gene expression databases

BgeeiENSG00000118197 Expressed in 214 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ5T1W1 baseline and differential

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T1W1_HUMAN
AccessioniPrimary (citable) accession number: Q5T1W1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 7, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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