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Entry version 107 (12 Aug 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Axonemal dynein light chain domain-containing protein 1

Gene

AXDND1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q5T1B0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Axonemal dynein light chain domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AXDND1
Synonyms:C1orf125
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000162779.20

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26564, AXDND1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5T1B0

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
126859

Open Targets

More...
OpenTargetsi
ENSG00000162779

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672443

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5T1B0, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
AXDND1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74744440

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002848681 – 1012Axonemal dynein light chain domain-containing protein 1Add BLAST1012

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5T1B0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5T1B0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5T1B0

PeptideAtlas

More...
PeptideAtlasi
Q5T1B0

PRoteomics IDEntifications database

More...
PRIDEi
Q5T1B0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
64252 [Q5T1B0-1]
64253 [Q5T1B0-2]
64254 [Q5T1B0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5T1B0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5T1B0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162779, Expressed in sperm and 111 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5T1B0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5T1B0, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000162779, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126021, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q5T1B0, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356590

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5T1B0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5T1B0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili317 – 402Sequence analysisAdd BLAST86
Coiled coili447 – 486Sequence analysisAdd BLAST40
Coiled coili572 – 597Sequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi824 – 1002Glu-richAdd BLAST179

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSV4, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005554

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5T1B0

Identification of Orthologs from Complete Genome Data

More...
OMAi
WINTCSC

Database of Orthologous Groups

More...
OrthoDBi
370082at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5T1B0

TreeFam database of animal gene trees

More...
TreeFami
TF314891

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019347, Axonemal_dynein_light_chain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10211, Ax_dynein_light, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T1B0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSLPKTPSTP LNSTSTSESK KLKVSVAKEG TRGLPELKEK KNMVDRSKLL
60 70 80 90 100
PTSLQNEFIP KEVLLSLTYA ANAGPCPENL LPPKKIKTPK GTLPRLVDHV
110 120 130 140 150
WHHPVRRNKF KYLIDHPVSL TGAGRDISFL YDVTYAKGQT REKAVCPPHL
160 170 180 190 200
ARSLQSHDGV IVPHKPKTLT DTLIPEEFHI VSSTGVSGLE CYDDKYTTLL
210 220 230 240 250
TDSENRLLLF PSMKPNKRVE VAQLNDVMDT MLERAGVENQ EYTGPTKMHK
260 270 280 290 300
LLHILKKEQT IYNMIFHELI RQVSVDCADR GELLSKVRER YVQMLDQIAR
310 320 330 340 350
QMIDFYKDLV TQRVMDQRIL EELYNFKHVI EELTRELCLV RAHDVKLTKE
360 370 380 390 400
TEKAHKDLAQ ALLNAEKNAK IVEEYHDLYT LQRERMENDM KKLVAERDIW
410 420 430 440 450
SSATYELALK VIERNRVILA RRLYLNEKGW NKYTKHFIIL LSNKDTEDLA
460 470 480 490 500
LLQKLTQKWR NLVNKLKQEV EQMEESTSET LKIVKDGLIK WQEFFNEKDI
510 520 530 540 550
LSPNKGNIFN SVLLDFKQWQ KILNEKKEEF TGDVLLSKYD TLKIIKHLQE
560 570 580 590 600
NWADIGLGIF NRHKSLEGEM PSERQYMEEI IKNIQKLYKE YEIRINGDNG
610 620 630 640 650
YSKILPSLIS SLDFCSFKLE NLEFPDTPLE EWQEIDEKIN EMKSHLDILL
660 670 680 690 700
NLTGIVPQHI DVDSVSVLQA YIFNMIQQWL LKIGNEINNG NIELQHHMDE
710 720 730 740 750
LHISMIQWMV NLLILMIPNF TDQDCLLKLE EESAEKHDIG VARLELDAIE
760 770 780 790 800
LTRKLYQYSS YLSSCCKGMV TAMALSKSTN SHKNATEDLY EVDKLKKECY
810 820 830 840 850
EWINTCSCLL SNIKGRKITL LTYEEIERLL EEEAVKEFIE PEIDESFKED
860 870 880 890 900
EEESKEDRKL QEENKERAEE QPSTSTEKEK LIRFIGEDEN VHSKPLFETD
910 920 930 940 950
VLSSWRESAK QGTLAQKYLE AMAVIEHMQE KLLEVENRAR QAEEKFEDAY
960 970 980 990 1000
EKLHHTLIKN KDLEELVMTS RKESKEEKEN QDEREVKEEE EQQEEEEVRS
1010
AENSSKSPKK GH
Length:1,012
Mass (Da):118,027
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i68FAFA863A251F87
GO
Isoform 2 (identifier: Q5T1B0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-212: Missing.
     600-655: GYSKILPSLI...LDILLNLTGI → ETGSHRVAQA...CEVTPKFFQV
     656-1012: Missing.

Show »
Length:443
Mass (Da):52,379
Checksum:i0889A103C9F8C33C
GO
Isoform 3 (identifier: Q5T1B0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-768: Missing.
     906-908: RES → KKV
     909-1012: Missing.

Show »
Length:140
Mass (Da):16,452
Checksum:iED8E0073D6E32A84
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6H900A6H900_HUMAN
Axonemal dynein light chain domain-...
AXDND1 C1orf125
529Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AM31B1AM31_HUMAN
Axonemal dynein light chain domain-...
AXDND1
872Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9B7D6R9B7_HUMAN
Axonemal dynein light chain domain-...
AXDND1
78Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6REE1D6REE1_HUMAN
Axonemal dynein light chain domain-...
AXDND1
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RDY4D6RDY4_HUMAN
Axonemal dynein light chain domain-...
AXDND1
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAH10571 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050705522I → L. Corresponds to variant dbSNP:rs11577579Ensembl.1
Natural variantiVAR_031841742A → V. Corresponds to variant dbSNP:rs17369441Ensembl.1
Natural variantiVAR_031842991E → Q. Corresponds to variant dbSNP:rs6425573Ensembl.1
Natural variantiVAR_050706993Q → E. Corresponds to variant dbSNP:rs6658180Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0247031 – 768Missing in isoform 3. 1 PublicationAdd BLAST768
Alternative sequenceiVSP_0247041 – 212Missing in isoform 2. 1 PublicationAdd BLAST212
Alternative sequenceiVSP_024705600 – 655GYSKI…NLTGI → ETGSHRVAQAGLKLLGSSDH PTSAPQSAGIRGIIHRTWPW VNFYIVCEVTPKFFQV in isoform 2. 1 PublicationAdd BLAST56
Alternative sequenceiVSP_024706656 – 1012Missing in isoform 2. 1 PublicationAdd BLAST357
Alternative sequenceiVSP_024707906 – 908RES → KKV in isoform 3. 1 Publication3
Alternative sequenceiVSP_024708909 – 1012Missing in isoform 3. 1 PublicationAdd BLAST104

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK057502 mRNA Translation: BAB71513.1
AK058167 mRNA Translation: BAB71698.1
BX647935 mRNA Translation: CAH10571.1 Frameshift.
AL160286 Genomic DNA No translation available.
AL451075 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30948.1 [Q5T1B0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_653297.3, NM_144696.5 [Q5T1B0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367618; ENSP00000356590; ENSG00000162779 [Q5T1B0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
126859

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:126859

UCSC genome browser

More...
UCSCi
uc001gmo.3, human [Q5T1B0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057502 mRNA Translation: BAB71513.1
AK058167 mRNA Translation: BAB71698.1
BX647935 mRNA Translation: CAH10571.1 Frameshift.
AL160286 Genomic DNA No translation available.
AL451075 Genomic DNA No translation available.
CCDSiCCDS30948.1 [Q5T1B0-1]
RefSeqiNP_653297.3, NM_144696.5 [Q5T1B0-1]

3D structure databases

SMRiQ5T1B0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi126021, 3 interactors
IntActiQ5T1B0, 4 interactors
STRINGi9606.ENSP00000356590

PTM databases

iPTMnetiQ5T1B0
PhosphoSitePlusiQ5T1B0

Polymorphism and mutation databases

BioMutaiAXDND1
DMDMi74744440

Proteomic databases

jPOSTiQ5T1B0
MassIVEiQ5T1B0
PaxDbiQ5T1B0
PeptideAtlasiQ5T1B0
PRIDEiQ5T1B0
ProteomicsDBi64252 [Q5T1B0-1]
64253 [Q5T1B0-2]
64254 [Q5T1B0-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
50119, 38 antibodies

Genome annotation databases

EnsembliENST00000367618; ENSP00000356590; ENSG00000162779 [Q5T1B0-1]
GeneIDi126859
KEGGihsa:126859
UCSCiuc001gmo.3, human [Q5T1B0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
126859
DisGeNETi126859
EuPathDBiHostDB:ENSG00000162779.20

GeneCards: human genes, protein and diseases

More...
GeneCardsi
AXDND1
HGNCiHGNC:26564, AXDND1
HPAiENSG00000162779, Tissue enriched (testis)
neXtProtiNX_Q5T1B0
OpenTargetsiENSG00000162779
PharmGKBiPA142672443

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QSV4, Eukaryota
GeneTreeiENSGT00390000005554
InParanoidiQ5T1B0
OMAiWINTCSC
OrthoDBi370082at2759
PhylomeDBiQ5T1B0
TreeFamiTF314891

Enzyme and pathway databases

PathwayCommonsiQ5T1B0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
126859, 5 hits in 870 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
AXDND1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
126859
PharosiQ5T1B0, Tdark

Protein Ontology

More...
PROi
PR:Q5T1B0
RNActiQ5T1B0, protein

Gene expression databases

BgeeiENSG00000162779, Expressed in sperm and 111 other tissues
ExpressionAtlasiQ5T1B0, baseline and differential
GenevisibleiQ5T1B0, HS

Family and domain databases

InterProiView protein in InterPro
IPR019347, Axonemal_dynein_light_chain
PfamiView protein in Pfam
PF10211, Ax_dynein_light, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAXDN1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T1B0
Secondary accession number(s): Q6AWB2, Q96LJ3, Q96M01
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 21, 2004
Last modified: August 12, 2020
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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