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Protein
Submitted name:

Protein Mdm4

Gene

MDM4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Mdm4Imported
Gene namesi
Name:MDM4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000198625.12
HGNCiHGNC:6974 MDM4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198625

PTM / Processingi

Proteomic databases

MaxQBiQ5T0Y2
PeptideAtlasiQ5T0Y2
PRIDEiQ5T0Y2

Expressioni

Gene expression databases

BgeeiENSG00000198625 Expressed in 219 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ5T0Y2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5T0Y2
SMRiQ5T0Y2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini185 – 213RanBP2-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IE9V Eukaryota
ENOG410XSWN LUCA
GeneTreeiENSGT00530000063539

Family and domain databases

InterProiView protein in InterPro
IPR015458 MDM4
IPR016495 p53_neg-reg_MDM_2/4
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
PANTHERiPTHR13844:SF20 PTHR13844:SF20, 1 hit
PfamiView protein in Pfam
PF00641 zf-RanBP, 1 hit
PIRSFiPIRSF006748 p53_MDM_2/4, 1 hit
SUPFAMiSSF90209 SSF90209, 1 hit
PROSITEiView protein in PROSITE
PS01358 ZF_RANBP2_1, 1 hit
PS50199 ZF_RANBP2_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q5T0Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPNFVVDWRV YTDSLFLTVD FGLCAEESST SRKRTTEDDI PTLPTSEHKC
60 70 80 90 100
IHSREDEDLI ENLAQDETSR LDLGFEEWDV AGLPWWFLGN LRSNYTPRSN
110 120 130 140 150
GSTDLQTNQD VGTAIVSDTT DDLWFLNESV SEQLGVGIKV EAADTEQTSE
160 170 180 190 200
EVGKVSDKKV IEVGKNDDLE DSKSLSDDTD VEVTSEDEWQ CTECKKFNSP
210
SKRYCFRCWA LRK
Length:213
Mass (Da):24,213
Last modified:December 21, 2004 - v1
Checksum:iB4DE78BC53238026
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15151MDM4_HUMAN
Protein Mdm4
MDM4 MDMX
490Annotation score:
A0A087WTR9A0A087WTR9_HUMAN
Protein Mdm4
MDM4
267Annotation score:
A0A087WZ58A0A087WZ58_HUMAN
Protein Mdm4
MDM4
392Annotation score:
Q5T0Y3Q5T0Y3_HUMAN
Protein Mdm4
MDM4
171Annotation score:
Q68DC0Q68DC0_HUMAN
MDM4 protein variant G
MDM4 DKFZp781B1423
140Annotation score:
A0A087WUE3A0A087WUE3_HUMAN
Protein Mdm4
MDM4
116Annotation score:
Q5T0Y4Q5T0Y4_HUMAN
Protein Mdm4
MDM4
131Annotation score:
Q6MZR7Q6MZR7_HUMAN
Protein Mdm4
MDM4 DKFZp686B01123
153Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei213Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512306 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000367179; ENSP00000356147; ENSG00000198625
UCSCiuc057orc.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512306 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5T0Y2
SMRiQ5T0Y2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ5T0Y2
PeptideAtlasiQ5T0Y2
PRIDEiQ5T0Y2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367179; ENSP00000356147; ENSG00000198625
UCSCiuc057orc.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000198625.12
HGNCiHGNC:6974 MDM4
OpenTargetsiENSG00000198625
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IE9V Eukaryota
ENOG410XSWN LUCA
GeneTreeiENSGT00530000063539

Miscellaneous databases

ChiTaRSiMDM4 human

Gene expression databases

BgeeiENSG00000198625 Expressed in 219 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ5T0Y2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR015458 MDM4
IPR016495 p53_neg-reg_MDM_2/4
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
PANTHERiPTHR13844:SF20 PTHR13844:SF20, 1 hit
PfamiView protein in Pfam
PF00641 zf-RanBP, 1 hit
PIRSFiPIRSF006748 p53_MDM_2/4, 1 hit
SUPFAMiSSF90209 SSF90209, 1 hit
PROSITEiView protein in PROSITE
PS01358 ZF_RANBP2_1, 1 hit
PS50199 ZF_RANBP2_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T0Y2_HUMAN
AccessioniPrimary (citable) accession number: Q5T0Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 12, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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