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Entry version 118 (26 Feb 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Protein FAM83B

Gene

FAM83B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM83BCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM83BImported
Synonyms:C6orf143Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21357 FAM83B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5T0W9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi230K → A: Loss of the ability to interact with and activate EGFR. 1 Publication1

Keywords - Diseasei

Proto-oncogene

Organism-specific databases

DisGeNET

More...
DisGeNETi
222584

Open Targets

More...
OpenTargetsi
ENSG00000168143

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134987811

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5T0W9 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM83B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74744366

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002975621 – 1011Protein FAM83BAdd BLAST1011

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei334PhosphoserineCombined sources1
Modified residuei422PhosphoserineCombined sources1
Modified residuei424PhosphoserineCombined sources1
Modified residuei466PhosphoserineCombined sources1
Modified residuei543PhosphoserineCombined sources1
Modified residuei664PhosphoserineCombined sources1
Modified residuei782PhosphothreonineCombined sources1
Modified residuei802PhosphoserineCombined sources1
Modified residuei852PhosphoserineCombined sources1
Modified residuei869PhosphoserineCombined sources1
Modified residuei915PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5T0W9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5T0W9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5T0W9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5T0W9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5T0W9

PeptideAtlas

More...
PeptideAtlasi
Q5T0W9

PRoteomics IDEntifications database

More...
PRIDEi
Q5T0W9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
64210

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5T0W9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5T0W9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000168143 Expressed in skin of abdomen and 58 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5T0W9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA031464
HPA031465

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with EGFR; the interaction is disrupted by EGF stimulation (PubMed:23912460).

Interacts with RAF1; displaces 14-3-3 proteins from RAF1 and activates RAF1 within the RAS/MAPK signaling cascade (PubMed:22886302).

Interacts with AKT1, PIK3CA and PIK3R1; activates the PI3K/AKT signaling cascade (PubMed:23676467).

3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128805, 33 interactors

Protein interaction database and analysis system

More...
IntActi
Q5T0W9, 28 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000304078

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5T0W9 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11011
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5T0W9

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 284Required for interaction with RAF1 and for the function1 PublicationAdd BLAST284

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi833 – 838Poly-Ser6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM83 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IK0Q Eukaryota
ENOG410ZVMG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157889

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011804_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5T0W9

Identification of Orthologs from Complete Genome Data

More...
OMAi
FYRMCSS

Database of Orthologous Groups

More...
OrthoDBi
103194at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5T0W9

TreeFam database of animal gene trees

More...
TreeFami
TF330777

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012461 FAM83_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07894 FAM83, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5T0W9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METSSMLSSL NDECKSDNYI EPHYKEWYRV AIDILIEHGL EAYQEFLVQE
60 70 80 90 100
RVSDFLAEEE INYILKNVQK VAQSTAHGTD DSCDDTLSSG TYWPVESDVE
110 120 130 140 150
APNLDLGWPY VMPGLLGGTH IDLLFHPPRA HLLTIKETIR KMIKEARKVI
160 170 180 190 200
ALVMDIFTDV DIFKEIVEAS TRGVSVYILL DESNFNHFLN MTEKQGCSVQ
210 220 230 240 250
RLRNIRVRTV KGQDYLSKTG AKFHGKMEQK FLLVDCQKVM YGSYSYMWSF
260 270 280 290 300
EKAHLSMVQI ITGQLVESFD EEFRTLYARS CVPSSFAQEE SARVKHGKAL
310 320 330 340 350
WENGTYQHSV SSLASVSSQR NLFGRQDKIH KLDSSYFKNR GIYTLNEHDK
360 370 380 390 400
YNIRSHGYKP HFVPNFNGPN AIRQFQPNQI NENWKRHSYA GEQPETVPYL
410 420 430 440 450
LLNRALNRTN NPPGNWKKPS DSLSVASSSR EGYVSHHNTP AQSFANRLAQ
460 470 480 490 500
RKTTNLADRN SNVRRSFNGT DNHIRFLQQR MPTLEHTTKS FLRNWRIESY
510 520 530 540 550
LNDHSEATPD SNGSALGDRF EGYDNPENLK ANALYTHSRL RSSLVFKPTL
560 570 580 590 600
PEQKEVNSCT TGSSNSTIIG SQGSETPKEV PDTPTNVQHL TDKPLPESIP
610 620 630 640 650
KLPLQSEAPK MHTLQVPENH SVALNQTTNG HTESNNYIYK TLGVNKQTEN
660 670 680 690 700
LKNQQTENLL KRRSFPLFDN SKANLDPGNS KHYVYSTLTR NRVRQPEKPK
710 720 730 740 750
EDLLKSSKSM HNVTHNLEED EEEVTKRNSP SGTTTKSVSI AALLDVNKEE
760 770 780 790 800
SNKELASKKE VKGSPSFLKK GSQKLRSLLS LTPDKKENLS KNKAPAFYRL
810 820 830 840 850
CSSSDTLVSE GEENQKPKKS DTKVDSSPRR KHSSSSNSQG SIHKSKEDVT
860 870 880 890 900
VSPSQEINAP PDENKRTPSP GPVESKFLER AGDASAPRFN TEQIQYRDSR
910 920 930 940 950
EINAVVTPER RPTSSPRPTS SELLRSHSTD RRVYSRFEPF CKIESSIQPT
960 970 980 990 1000
SNMPNTSINR PEIKSATMGN SYGRSSPLLN YNTGVYRSYQ PNENKFRGFM
1010
QKFGNFIHKN K
Length:1,011
Mass (Da):114,799
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7EF02DC36F95CFC3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti349D → G in BAB70873 (PubMed:14702039).Curated1
Sequence conflicti417K → E in BAB70873 (PubMed:14702039).Curated1
Sequence conflicti541R → S in BAB70873 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034638410N → S. Corresponds to variant dbSNP:rs13211183Ensembl.1
Natural variantiVAR_034639435S → R. Corresponds to variant dbSNP:rs9475076Ensembl.1
Natural variantiVAR_034640640K → T1 PublicationCorresponds to variant dbSNP:rs239798Ensembl.1
Natural variantiVAR_034641907T → N1 PublicationCorresponds to variant dbSNP:rs9475077Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL512363 Genomic DNA No translation available.
AL049555 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX04439.1
BC101628 mRNA Translation: AAI01629.1
BC112275 mRNA Translation: AAI12276.1
AK055204 mRNA Translation: BAB70873.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34479.1

NCBI Reference Sequences

More...
RefSeqi
NP_001010872.1, NM_001010872.2
XP_006715085.1, XM_006715022.3
XP_011512696.1, XM_011514394.2
XP_011512697.1, XM_011514395.2
XP_016865967.1, XM_017010478.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000306858; ENSP00000304078; ENSG00000168143

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
222584

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:222584

UCSC genome browser

More...
UCSCi
uc003pck.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512363 Genomic DNA No translation available.
AL049555 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX04439.1
BC101628 mRNA Translation: AAI01629.1
BC112275 mRNA Translation: AAI12276.1
AK055204 mRNA Translation: BAB70873.1
CCDSiCCDS34479.1
RefSeqiNP_001010872.1, NM_001010872.2
XP_006715085.1, XM_006715022.3
XP_011512696.1, XM_011514394.2
XP_011512697.1, XM_011514395.2
XP_016865967.1, XM_017010478.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5LZKX-ray1.57A/B117-294[»]
5QHIX-ray1.73A/B117-294[»]
5QHJX-ray1.68A/B117-294[»]
5QHKX-ray1.61A/B117-294[»]
5QHLX-ray1.68A/B117-294[»]
5QHMX-ray1.79A117-294[»]
5QHNX-ray1.73A117-294[»]
5QHOX-ray1.66A117-294[»]
5QHPX-ray2.06A117-294[»]
5QHQX-ray1.96A117-294[»]
5QHRX-ray1.68A117-294[»]
5QHSX-ray1.95A117-294[»]
SMRiQ5T0W9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi128805, 33 interactors
IntActiQ5T0W9, 28 interactors
STRINGi9606.ENSP00000304078

PTM databases

iPTMnetiQ5T0W9
PhosphoSitePlusiQ5T0W9

Polymorphism and mutation databases

BioMutaiFAM83B
DMDMi74744366

Proteomic databases

EPDiQ5T0W9
jPOSTiQ5T0W9
MassIVEiQ5T0W9
MaxQBiQ5T0W9
PaxDbiQ5T0W9
PeptideAtlasiQ5T0W9
PRIDEiQ5T0W9
ProteomicsDBi64210

Genome annotation databases

EnsembliENST00000306858; ENSP00000304078; ENSG00000168143
GeneIDi222584
KEGGihsa:222584
UCSCiuc003pck.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
222584
DisGeNETi222584

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM83B
HGNCiHGNC:21357 FAM83B
HPAiHPA031464
HPA031465
neXtProtiNX_Q5T0W9
OpenTargetsiENSG00000168143
PharmGKBiPA134987811

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IK0Q Eukaryota
ENOG410ZVMG LUCA
GeneTreeiENSGT00940000157889
HOGENOMiCLU_011804_0_0_1
InParanoidiQ5T0W9
OMAiFYRMCSS
OrthoDBi103194at2759
PhylomeDBiQ5T0W9
TreeFamiTF330777

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM83B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
222584
PharosiQ5T0W9 Tbio

Protein Ontology

More...
PROi
PR:Q5T0W9
RNActiQ5T0W9 protein

Gene expression databases

BgeeiENSG00000168143 Expressed in skin of abdomen and 58 other tissues
GenevisibleiQ5T0W9 HS

Family and domain databases

InterProiView protein in InterPro
IPR012461 FAM83_N
PfamiView protein in Pfam
PF07894 FAM83, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFA83B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T0W9
Secondary accession number(s): Q2M1P3, Q96DQ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: December 21, 2004
Last modified: February 26, 2020
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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