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Entry version 132 (08 May 2019)
Sequence version 3 (14 May 2014)
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Protein

Cilia- and flagella-associated protein 70

Gene

CFAP70

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cilia- and flagella-associated protein 70Imported
Alternative name(s):
Tetratricopeptide repeat protein 18Curated
Short name:
TPR repeat protein 18Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CFAP70Imported
Synonyms:TTC18Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30726 CFAP70

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5T0N1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Cilium

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000156042

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134881300

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CFAP70

Domain mapping of disease mutations (DMDM)

More...
DMDMi
294862471

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002919131 – 1121Cilia- and flagella-associated protein 70Add BLAST1121

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5T0N1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5T0N1

PeptideAtlas

More...
PeptideAtlasi
Q5T0N1

PRoteomics IDEntifications database

More...
PRIDEi
Q5T0N1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
64180
64181 [Q5T0N1-2]
64182 [Q5T0N1-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5T0N1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5T0N1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000156042 Expressed in 162 organ(s), highest expression level in bronchial epithelial cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5T0N1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5T0N1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA037582
HPA070304

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000310829

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati635 – 668TPR 1Add BLAST34
Repeati669 – 702TPR 2Add BLAST34
Repeati704 – 736TPR 3Add BLAST33
Repeati929 – 962TPR 4Add BLAST34
Repeati963 – 996TPR 5Add BLAST34
Repeati1000 – 1033TPR 6Add BLAST34
Repeati1035 – 1066TPR 7Add BLAST32
Repeati1068 – 1100TPR 8Add BLAST33

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CFAP70 family.Curated

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE2V Eukaryota
ENOG410YIJC LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013319

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5T0N1

Identification of Orthologs from Complete Genome Data

More...
OMAi
RIIWDLE

Database of Orthologous Groups

More...
OrthoDBi
260340at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5T0N1

TreeFam database of animal gene trees

More...
TreeFami
TF324454

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13181 TPR_8, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50005 TPR, 7 hits
PS50293 TPR_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5T0N1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEQVPSAGRL VQITVTEGYD LKGFKGDTPV TFIRAEFNQV VLGDSAKITV
60 70 80 90 100
SPEGSAKYNF TSSFEFNPEG GITSDDLAHK PVFLTVTEVL PKEKKQKEEK
110 120 130 140 150
TLILGQAVVD LLPLLEGQSS FQTTVPLHPV QGSPLETPRS SAKQCSLEVK
160 170 180 190 200
VLVAEPLLTT AQISGGNLLK VTLEAAYSVP ESFIPTGPGQ NYMVGLQVPS
210 220 230 240 250
LGEKDYPILF KNGTLKLGGE REPVPRPKKW PIANILAPGA NNIPDAFIVG
260 270 280 290 300
GPYEEEEGEL NHPEDSEFRN QAECIKKRII WDLESRCYLD PSAVVSFQKR
310 320 330 340 350
IADCRLWPVE ITRVPLVTIP KGKAGKTEKT DEEAQLSFHG VAYVNMVPLL
360 370 380 390 400
YPGVKRIRGA FHVYPYLDSV VHEKTKCLLS LFRDIGHHLI HNNKIGGINS
410 420 430 440 450
LLSKQAVSKN LKEDKPVKEK DIDGRPRPGD VQAPSIKSQS SDTPLEGEPP
460 470 480 490 500
LSHNPEGQQY VEAGTYIVLE IQLDKALVPK RMPEELARRV KEMIPPRPPL
510 520 530 540 550
TRRTGGAQKA MSDYHIQIKN ISRAILDEYY RMFGKQVAKL ESDMDSETLE
560 570 580 590 600
EQKCQLSYEL NCSGKYFAFK EQLKHAVVKI VRDKYLKTTS FESQEELQTF
610 620 630 640 650
ISELYVFLVD QMHVALNQTM PDDVQGTVAT IYTSSEQLQL FAFEAEVNEN
660 670 680 690 700
FEMAAAYYKE RLVREPQNLD HWLDYGAFCL LTEDNIKAQE CFQKALSLNQ
710 720 730 740 750
SHIHSLLLCG VLAVLLENYE QAEIFFEDAT CLEPTNVVAW TLLGLYYEIQ
760 770 780 790 800
NNDIRMEMAF HEASKQLQAR MLQAQVTKQK STGVEDTEER GKRESSLGPW
810 820 830 840 850
GITNGSATAI KVEAPAGPGA ALSILDKFLE ESSKLQSDSQ EPILTTQTWD
860 870 880 890 900
PSISQKPSNT FIKEIPTKKE ASKCQDSSAL LHPGLHYGVS QTTTIFMETI
910 920 930 940 950
HFLMKVKAVQ YVHRVLAHEL LCPQGGPSCE YYLVLAQTHI LKKNFAKAEE
960 970 980 990 1000
YLQQAAQMDY LNPNVWGLKG HLYFLSGNHS EAKACYERTI SFVVDASEMH
1010 1020 1030 1040 1050
FIFLRLGLIY LEEKEYEKAK KTYMQACKRS PSCLTWLGLG IACYRLEELT
1060 1070 1080 1090 1100
EAEDALSEAN ALNNYNAEVW AYLALVCLKV GRQLEAEQAY KYMIKLKLKD
1110 1120
EALLAEIHTL QETVGFGNPS F
Length:1,121
Mass (Da):125,721
Last modified:May 14, 2014 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i480F4EAFFC149775
GO
Isoform 2 (identifier: Q5T0N1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1016-1045: Missing.

Show »
Length:1,091
Mass (Da):122,269
Checksum:i5029425912AFBCDC
GO
Isoform 3 (identifier: Q5T0N1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     117-119: GQS → VQS
     120-1121: Missing.

Note: No experimental confirmation available.
Show »
Length:119
Mass (Da):12,999
Checksum:iC976105F75ACBDC1
GO
Isoform 4 (identifier: Q5T0N1-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-896: Missing.
     1016-1045: Missing.

Note: No experimental confirmation available.
Show »
Length:195
Mass (Da):22,338
Checksum:i1D5B5261D4C900AE
GO
Isoform 5 (identifier: Q5T0N1-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-896: Missing.

Note: No experimental confirmation available.
Show »
Length:225
Mass (Da):25,790
Checksum:i8367171B8BACB2C5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WSW1A0A087WSW1_HUMAN
Cilia- and flagella-associated prot...
CFAP70
590Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X6RID7X6RID7_HUMAN
Cilia- and flagella-associated prot...
CFAP70
498Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X6R507X6R507_HUMAN
Cilia- and flagella-associated prot...
CFAP70
361Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MS55A0A0A0MS55_HUMAN
Cilia- and flagella-associated prot...
CFAP70
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAM20909 differs from that shown. Reason: Frameshift at several positions.Curated
The sequence AAM20910 differs from that shown. Reason: Frameshift at several positions.Curated
The sequence BAC05358 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti79H → Y in CAH10391 (PubMed:17974005).Curated1
Sequence conflicti511M → V in AAH32856 (PubMed:15489334).Curated1
Sequence conflicti922C → R in AAM20909 (Ref. 5) Curated1
Sequence conflicti922C → R in AAM20910 (Ref. 5) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032877849W → L. Corresponds to variant dbSNP:rs12256262Ensembl.1
Natural variantiVAR_032878944N → D. Corresponds to variant dbSNP:rs4294502Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0544611 – 896Missing in isoform 4 and isoform 5. 1 PublicationAdd BLAST896
Alternative sequenceiVSP_054462117 – 119GQS → VQS in isoform 3. 1 Publication3
Alternative sequenceiVSP_026289120 – 1121Missing in isoform 3. 1 PublicationAdd BLAST1002
Alternative sequenceiVSP_0262911016 – 1045Missing in isoform 2 and isoform 4. 2 PublicationsAdd BLAST30

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL833537 mRNA Translation: CAH10391.1 Different termination.
AC016394 Genomic DNA No translation available.
AL512656 Genomic DNA No translation available.
BC032856 mRNA Translation: AAH32856.1
AK098631 mRNA Translation: BAC05358.1 Different initiation.
AF435958 mRNA Translation: AAM20909.1 Frameshift.
AF435959 mRNA Translation: AAM20910.1 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_660153.3, NM_145170.3
XP_006717667.1, XM_006717604.2
XP_006717668.1, XM_006717605.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000310715; ENSP00000310829; ENSG00000156042 [Q5T0N1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
118491

UCSC genome browser

More...
UCSCi
uc009xrc.4 human [Q5T0N1-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL833537 mRNA Translation: CAH10391.1 Different termination.
AC016394 Genomic DNA No translation available.
AL512656 Genomic DNA No translation available.
BC032856 mRNA Translation: AAH32856.1
AK098631 mRNA Translation: BAC05358.1 Different initiation.
AF435958 mRNA Translation: AAM20909.1 Frameshift.
AF435959 mRNA Translation: AAM20910.1 Frameshift.
RefSeqiNP_660153.3, NM_145170.3
XP_006717667.1, XM_006717604.2
XP_006717668.1, XM_006717605.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000310829

PTM databases

iPTMnetiQ5T0N1
PhosphoSitePlusiQ5T0N1

Polymorphism and mutation databases

BioMutaiCFAP70
DMDMi294862471

Proteomic databases

EPDiQ5T0N1
PaxDbiQ5T0N1
PeptideAtlasiQ5T0N1
PRIDEiQ5T0N1
ProteomicsDBi64180
64181 [Q5T0N1-2]
64182 [Q5T0N1-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000310715; ENSP00000310829; ENSG00000156042 [Q5T0N1-1]
GeneIDi118491
UCSCiuc009xrc.4 human [Q5T0N1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
118491

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CFAP70

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0201492
HGNCiHGNC:30726 CFAP70
HPAiHPA037582
HPA070304
neXtProtiNX_Q5T0N1
OpenTargetsiENSG00000156042
PharmGKBiPA134881300

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE2V Eukaryota
ENOG410YIJC LUCA
GeneTreeiENSGT00390000013319
InParanoidiQ5T0N1
OMAiRIIWDLE
OrthoDBi260340at2759
PhylomeDBiQ5T0N1
TreeFamiTF324454

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CFAP70 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
118491

Protein Ontology

More...
PROi
PR:Q5T0N1

Gene expression databases

BgeeiENSG00000156042 Expressed in 162 organ(s), highest expression level in bronchial epithelial cell
ExpressionAtlasiQ5T0N1 baseline and differential
GenevisibleiQ5T0N1 HS

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF13181 TPR_8, 3 hits
SMARTiView protein in SMART
SM00028 TPR, 9 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 7 hits
PS50293 TPR_REGION, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCFA70_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5T0N1
Secondary accession number(s): C9JIZ9
, Q5T0M4, Q5T0M9, Q5T0N0, Q69YH9, Q8IYZ8, Q8N7D5, Q8NI30, Q8NI31
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: May 14, 2014
Last modified: May 8, 2019
This is version 132 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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