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Protein

Annexin

Gene

ANXA11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandCalcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:ANXA11Imported
ORF Names:hCG_22492Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000122359.17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24825

PTM / Processingi

Proteomic databases

MaxQBiQ5T0G8
PRIDEiQ5T0G8

Expressioni

Gene expression databases

BgeeiENSG00000122359
ExpressionAtlasiQ5T0G8 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ5T0G8, 3 interactors

Structurei

3D structure databases

SMRiQ5T0G8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0819 Eukaryota
ENOG410XPUN LUCA
HOVERGENiHBG061815
KOiK17095
OMAiFDAYEIK
OrthoDBiEOG091G0H6H

Family and domain databases

Gene3Di1.10.220.10, 4 hits
InterProiView protein in InterPro
IPR001464 Annexin
IPR018502 Annexin_repeat
IPR018252 Annexin_repeat_CS
IPR037104 Annexin_sf
IPR008157 ANX11
PANTHERiPTHR10502:SF29 PTHR10502:SF29, 1 hit
PfamiView protein in Pfam
PF00191 Annexin, 4 hits
PRINTSiPR00196 ANNEXIN
PR01810 ANNEXINXI
SMARTiView protein in SMART
SM00335 ANX, 4 hits
PROSITEiView protein in PROSITE
PS00223 ANNEXIN, 3 hits

Sequencei

Sequence statusi: Complete.

Q5T0G8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYPGYPPPP GGYPPAAPGG GPWGGAAYPP PPSMPPIGLD NVATYAGQFN
60 70 80 90 100
QDYLSGMAAN MSGTFGGANM PNLYPGAPGA GYPPVPPGGF GQPPSAQQPV
110 120 130 140 150
PPYGMYPPPG GNPPSRMPSY PPYPGAPVPG QPMPPPGQQP PGAYPGQPPV
160 170 180 190 200
TYPGQPPVPL PGQQQPVPSY PGYPGSGTVT PAVPPTQFGS RGTITDAPGF
210 220 230 240 250
DPLRDAEVLR KAMKGFGTDE QAIIDCLGSR SNKQRQQILL SFKTAYGKDL
260 270 280 290 300
IKDLKSELSG NFEKTILALM KTPVLFDIYE IKEAIKGVGT DEACLIEILA
310 320 330 340 350
SRSNEHIREL NRAYKAEFKK TLEEAIRSDT SGHFQRLLIS LSQGNRDEST
360 370 380 390 400
NVDMSLAQRD AQELYAAGEN RLGTDESKFN AVLCSRSRAH LVAVFNEYQR
410 420 430 440 450
MTGRDIEKSI CREMSGDLEE GMLAVVKCLK NTPAFFAERL NKAMRGAGTK
460 470 480 490 500
DRTLIRIMVS RSETDLLDIR SEYKRMYGKS LYHDISGDTS GDYRKILLKI

CGGND
Length:505
Mass (Da):54,390
Last modified:May 10, 2005 - v1
Checksum:i4ADCAC8F270BFEE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056107 mRNA Translation: BAG51628.1
AK126287 mRNA Translation: BAG54303.1
CH471142 Genomic DNA Translation: EAW80400.1
CH471142 Genomic DNA Translation: EAW80401.1
CH471142 Genomic DNA Translation: EAW80402.1
CH471142 Genomic DNA Translation: EAW80403.1
CH471142 Genomic DNA Translation: EAW80404.1
CH471142 Genomic DNA Translation: EAW80405.1
RefSeqiNP_001148.1, NM_001157.2
NP_001265336.1, NM_001278407.1
NP_001265337.1, NM_001278408.1
NP_665875.1, NM_145868.1
NP_665876.1, NM_145869.1
XP_011538038.1, XM_011539736.2
UniGeneiHs.530291

Genome annotation databases

GeneIDi311
KEGGihsa:311
UCSCiuc001kbr.2 human

Similar proteinsi

Entry informationi

Entry nameiQ5T0G8_HUMAN
AccessioniPrimary (citable) accession number: Q5T0G8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 20, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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