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UniProtKB - Q5SZV5 (K0319_MOUSE)

Entry version 119 (07 Apr 2021)
Sequence version 1 (21 Dec 2004)
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Protein

Dyslexia-associated protein KIAA0319 homolog

Gene

Kiaa0319

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processNeurogenesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-8856825, Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828, Clathrin-mediated endocytosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dyslexia-associated protein KIAA0319 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kiaa0319
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:3036268, D130043K22Rik

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini23 – 964ExtracellularSequence analysisAdd BLAST942
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei965 – 985HelicalSequence analysisAdd BLAST21
Topological domaini986 – 1081CytoplasmicSequence analysisAdd BLAST96

Keywords - Cellular componenti

Cell membrane, Endosome, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004294723 – 1081Dyslexia-associated protein KIAA0319 homologAdd BLAST1059

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi196N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi228N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi272N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi302N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi430N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi507N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi522N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi545N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi560N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi742N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1009PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.By similarity
O-glycosylated.By similarity
Shedding of the extracellular domain and intramembrane cleavage produce several proteolytic products. The intramembrane cleavage releases a soluble cytoplasmic polypeptide that translocates to the nucleolus (By similarity).By similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5SZV5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5SZV5

PRoteomics IDEntifications database

More...PRIDEi		Q5SZV5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		269038

PTM databases

GlyConnect protein glycosylation platform

More...GlyConnecti		2268, 2 N-Linked glycans (1 site)

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q5SZV5, 10 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5SZV5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5SZV5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in the frontal neocortex, glanglionic eminence, mesencephalon and cerebellum at 13.5 dpc. More prominently expressed in the developing cerebral neocortex and mesencephalon at 15.5 dpc and in the cortical plate and in the remnant of the ventricular zone at 18.5 dpc.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000006711, Expressed in ventromedial nucleus of hypothalamus and 152 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5SZV5, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Interacts with AP2M1; required for clathrin-mediated endocytosis (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		229131, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q5SZV5, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000006893

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5SZV5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5SZV5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 99MANSCPROSITE-ProRule annotationAdd BLAST77
Domaini345 – 436PKD 1PROSITE-ProRule annotationAdd BLAST92
Domaini444 – 533PKD 2PROSITE-ProRule annotationAdd BLAST90
Domaini539 – 629PKD 3PROSITE-ProRule annotationAdd BLAST91
Domaini630 – 723PKD 4PROSITE-ProRule annotationAdd BLAST94
Domaini729 – 820PKD 5PROSITE-ProRule annotationAdd BLAST92

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1004 – 1007Endocytosis signal4

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QR8M, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161462

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_009448_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5SZV5

Identification of Orthologs from Complete Genome Data

More...OMAi		WSVFYVT

Database of Orthologous Groups

More...OrthoDBi		476157at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5SZV5

TreeFam database of animal gene trees

More...TreeFami		TF323356

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013783, Ig-like_fold
IPR029865, KIAA0319-like
IPR013980, MANSC_dom
IPR011106, MANSC_N
IPR022409, PKD/Chitinase_dom
IPR000601, PKD_dom
IPR035986, PKD_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR46182, PTHR46182, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00765, MANEC, 1 hit
SM00089, PKD, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49299, SSF49299, 4 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50986, MANSC, 1 hit
PS50093, PKD, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5SZV5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSPPGVLSS LLLLAAMAGG SSQQCSEGRT YSDAIISPNP ETIRIMRVSQ 
        60         70         80         90        100
TFSVGDCTAA CCDLLTCDLA WWFEGSCYLV KCMRSENCEP RTTGPIRSYL 
       110        120        130        140        150
TFVRRPVQRP GQLLDYGDMM LSRGSPSGAW GDSLEDLRKD LPFLGKDGGP 
       160        170        180        190        200
EETTEYSDEY KDLERGLLQP SNQQDPRGSA EYPDWSLLPS NEGGFNATAT 
       210        220        230        240        250
GDNSAASMEK LQDPTPHPLD QEQLQALNES TWSPTPGHSS ISSVWPSSAS 
       260        270        280        290        300
PLPTEEGLEG EETLQLQEQP SNSSGKEVPM PSHNPSPASL ESSPATTEKN 
       310        320        330        340        350
SNFTVTPRSR KHSTPTFPTS TVLTGLTPPP WPLSPTASRT VKALAVSAGD 
       360        370        380        390        400
NLVLTLPDRE AELKASVEPA PPADTTYSYE WSLMSHPVDF QGKIKQENKP 
       410        420        430        440        450
TLHLSQLSVG LYAFRVAVSS ENAFGEGYVN VTVMPAARVN QPPVAVVSPQ 
       460        470        480        490        500
TQELSVPLTS ALIDGSQSTD DTEIVSYHWE EVDGPFLGEE FPADTPILRL 
       510        520        530        540        550
SNLVPGNYTF RLTITDSDGA TNSTTASLVI RDAVDYPPVA NAGPNQTITL 
       560        570        580        590        600
PQNTIILNGN QSSDDHQIVL YEWFAGPGGE SKEMVMQGAQ TPYLHLSELQ 
       610        620        630        640        650
EGEYTFQLMV TDSSGQQSTA LVAVTVQAEN NQAPVAVAGP DKELVFPVQS 
       660        670        680        690        700
ATLDGSRSSD DHGIVCYHWE HIRGPSAVEM ENVDKAIATV TGLQVGIYHF 
       710        720        730        740        750
RLTVRDQQGL SSTSTLTVAV KKENNSPPRA QAGGRHVLIL PNNSITLDGS 
       760        770        780        790        800
RSTDDRGIVS YLWIRDGQSP AAGDVIGGSD HRAALQLTNL VEGVYTFHLL 
       810        820        830        840        850
VTDSQGASDS DAATVEVLPD PKKDGLVELI LQVGVEQLTE QQKETLVRQL 
       860        870        880        890        900
AVLLNVLDSD VKVLKIQAHT DVSTVIVFYV QSGSPFKVLR AAAVARNLHK 
       910        920        930        940        950
RLSKEKEAFL LFKVLRVDTA GCLLKCSGHG HCDPITKRCI CSQLWMENLI 
       960        970        980        990       1000
QRYMWDGESN CEWSVFYVAA LALTLTLLTG AVSWLCICCC RRRKRTKIRK 
      1010       1020       1030       1040       1050
KTKYTILDSM DEQERMELRP KYGIKHRSTE HNSSLMVSES EFESDQDTLF 
      1060       1070       1080 
SRERMERGVL KGSLNGCARN GVSFGYYSKD R
Length:1,081
Mass (Da):117,988
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC142C9746D9AF4DA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z497F2Z497_MOUSE
RIKEN cDNA D130043K22 gene
D130043K22Rik
782Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC65528 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK122246 mRNA Translation: BAC65528.1 Different initiation.
AL589699 Genomic DNA Translation: CAI26085.1
BC115723 mRNA Translation: AAI15724.1
BC115940 mRNA Translation: AAI15941.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS36624.1

NCBI Reference Sequences

More...RefSeqi		NP_001074520.1, NM_001081051.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000006893; ENSMUSP00000006893; ENSMUSG00000006711

Database of genes from NCBI RefSeq genomes

More...GeneIDi		210108

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:210108

UCSC genome browser

More...UCSCi		uc007pwn.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122246 mRNA Translation: BAC65528.1 Different initiation.
AL589699 Genomic DNA Translation: CAI26085.1
BC115723 mRNA Translation: AAI15724.1
BC115940 mRNA Translation: AAI15941.1
CCDSiCCDS36624.1
RefSeqiNP_001074520.1, NM_001081051.2

3D structure databases

SMRiQ5SZV5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi229131, 1 interactor
IntActiQ5SZV5, 1 interactor
STRINGi10090.ENSMUSP00000006893

PTM databases

GlyConnecti2268, 2 N-Linked glycans (1 site)
GlyGeniQ5SZV5, 10 sites
iPTMnetiQ5SZV5
PhosphoSitePlusiQ5SZV5

Proteomic databases

MaxQBiQ5SZV5
PaxDbiQ5SZV5
PRIDEiQ5SZV5
ProteomicsDBi269038

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2465, 120 antibodies

Genome annotation databases

EnsembliENSMUST00000006893; ENSMUSP00000006893; ENSMUSG00000006711
GeneIDi210108
KEGGimmu:210108
UCSCiuc007pwn.1, mouse

Organism-specific databases

MGIiMGI:3036268, D130043K22Rik

Rodent Unidentified Gene-Encoded large proteins database

More...Rougei		Search...

Phylogenomic databases

eggNOGiENOG502QR8M, Eukaryota
GeneTreeiENSGT00940000161462
HOGENOMiCLU_009448_0_1_1
InParanoidiQ5SZV5
OMAiWSVFYVT
OrthoDBi476157at2759
PhylomeDBiQ5SZV5
TreeFamiTF323356

Enzyme and pathway databases

ReactomeiR-MMU-8856825, Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828, Clathrin-mediated endocytosis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		210108, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		D130043K22Rik, mouse

Protein Ontology

More...PROi		PR:Q5SZV5
RNActiQ5SZV5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000006711, Expressed in ventromedial nucleus of hypothalamus and 152 other tissues
GenevisibleiQ5SZV5, MM

Family and domain databases

Gene3Di2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR013783, Ig-like_fold
IPR029865, KIAA0319-like
IPR013980, MANSC_dom
IPR011106, MANSC_N
IPR022409, PKD/Chitinase_dom
IPR000601, PKD_dom
IPR035986, PKD_dom_sf
PANTHERiPTHR46182, PTHR46182, 1 hit
SMARTiView protein in SMART
SM00765, MANEC, 1 hit
SM00089, PKD, 5 hits
SUPFAMiSSF49299, SSF49299, 4 hits
PROSITEiView protein in PROSITE
PS50986, MANSC, 1 hit
PS50093, PKD, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK0319_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SZV5
Secondary accession number(s): Q14BF3, Q80U39
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: December 21, 2004
Last modified: April 7, 2021
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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