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Protein

Uncharacterized protein C6orf141

Gene

C6orf141

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C6orf141
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000197261.11
HGNCiHGNC:21351 C6orf141
neXtProtiNX_Q5SZD1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197261
PharmGKBiPA134885117

Polymorphism and mutation databases

BioMutaiC6orf141
DMDMi317373454

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000895371 – 244Uncharacterized protein C6orf141Add BLAST244

Proteomic databases

PaxDbiQ5SZD1
PeptideAtlasiQ5SZD1
PRIDEiQ5SZD1
ProteomicsDBi64054

PTM databases

iPTMnetiQ5SZD1
PhosphoSitePlusiQ5SZD1

Expressioni

Gene expression databases

BgeeiENSG00000197261 Expressed in 132 organ(s), highest expression level in caudate nucleus
CleanExiHS_C6orf141
ExpressionAtlasiQ5SZD1 baseline and differential
GenevisibleiQ5SZD1 HS

Organism-specific databases

HPAiHPA036199

Interactioni

Protein-protein interaction databases

BioGridi126429, 85 interactors
IntActiQ5SZD1, 3 interactors

Structurei

3D structure databases

ProteinModelPortaliQ5SZD1
SMRiQ5SZD1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IY9G Eukaryota
ENOG4111419 LUCA
GeneTreeiENSGT00390000007738
HOVERGENiHBG058140
InParanoidiQ5SZD1
OMAiRESWVRE
OrthoDBiEOG091G0UG7
PhylomeDBiQ5SZD1
TreeFamiTF336881

Family and domain databases

InterProiView protein in InterPro
IPR037739 C6orf141
PANTHERiPTHR36880 PTHR36880, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5SZD1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDPFARMET RGPQGAANPM DSSRSLGDLG PFPREVGRGA PLAPGARNPA
60 70 80 90 100
TAGASRSQGG GHEDRTADRA LGPRAGEELD RESWVREKVL FLLHPERWLG
110 120 130 140 150
TRGDPAREEV AGAEDLPHAG GEDHGEEPNY PSVFQRQKRI SGRRVAPPRD
160 170 180 190 200
AADPPKYVLV RVEDYQVTQE VLQTSWAKGR MTTRTEEHFV TALTFRSSRE
210 220 230 240
GQPGERWGPA ESRALQARTG ASRVHAAGRR VSPSPGTWLE EIKL
Length:244
Mass (Da):26,754
Last modified:January 11, 2011 - v3
Checksum:iB2EE557D7AE9FBF2
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YDR2H0YDR2_HUMAN
Uncharacterized protein C6orf141
C6orf141
72Annotation score:

Sequence cautioni

The sequence AAH36917 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_022939137Q → E3 PublicationsCorresponds to variant dbSNP:rs6919674Ensembl.1
Natural variantiVAR_030643235P → L. Corresponds to variant dbSNP:rs9473588Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK054918 mRNA Translation: BAB70828.1
AK289889 mRNA Translation: BAF82578.1
AL590244 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX04335.1
BC036917 mRNA Translation: AAH36917.1 Different initiation.
CCDSiCCDS55018.1
RefSeqiNP_001139124.1, NM_001145652.1
XP_005248907.1, XM_005248850.3
XP_005248909.1, XM_005248852.2
XP_005248910.1, XM_005248853.2
XP_006715060.1, XM_006714997.2
XP_011512605.1, XM_011514303.2
XP_016865783.1, XM_017010294.1
XP_016865784.1, XM_017010295.1
XP_016865785.1, XM_017010296.1
XP_016865786.1, XM_017010297.1
XP_016865787.1, XM_017010298.1
UniGeneiHs.722010

Genome annotation databases

EnsembliENST00000371194; ENSP00000431184; ENSG00000197261
ENST00000414696; ENSP00000436754; ENSG00000197261
ENST00000529246; ENSP00000434602; ENSG00000197261
GeneIDi135398
KEGGihsa:135398
UCSCiuc011dwo.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK054918 mRNA Translation: BAB70828.1
AK289889 mRNA Translation: BAF82578.1
AL590244 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX04335.1
BC036917 mRNA Translation: AAH36917.1 Different initiation.
CCDSiCCDS55018.1
RefSeqiNP_001139124.1, NM_001145652.1
XP_005248907.1, XM_005248850.3
XP_005248909.1, XM_005248852.2
XP_005248910.1, XM_005248853.2
XP_006715060.1, XM_006714997.2
XP_011512605.1, XM_011514303.2
XP_016865783.1, XM_017010294.1
XP_016865784.1, XM_017010295.1
XP_016865785.1, XM_017010296.1
XP_016865786.1, XM_017010297.1
XP_016865787.1, XM_017010298.1
UniGeneiHs.722010

3D structure databases

ProteinModelPortaliQ5SZD1
SMRiQ5SZD1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126429, 85 interactors
IntActiQ5SZD1, 3 interactors

PTM databases

iPTMnetiQ5SZD1
PhosphoSitePlusiQ5SZD1

Polymorphism and mutation databases

BioMutaiC6orf141
DMDMi317373454

Proteomic databases

PaxDbiQ5SZD1
PeptideAtlasiQ5SZD1
PRIDEiQ5SZD1
ProteomicsDBi64054

Protocols and materials databases

DNASUi135398
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000371194; ENSP00000431184; ENSG00000197261
ENST00000414696; ENSP00000436754; ENSG00000197261
ENST00000529246; ENSP00000434602; ENSG00000197261
GeneIDi135398
KEGGihsa:135398
UCSCiuc011dwo.3 human

Organism-specific databases

CTDi135398
EuPathDBiHostDB:ENSG00000197261.11
GeneCardsiC6orf141
HGNCiHGNC:21351 C6orf141
HPAiHPA036199
neXtProtiNX_Q5SZD1
OpenTargetsiENSG00000197261
PharmGKBiPA134885117
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IY9G Eukaryota
ENOG4111419 LUCA
GeneTreeiENSGT00390000007738
HOVERGENiHBG058140
InParanoidiQ5SZD1
OMAiRESWVRE
OrthoDBiEOG091G0UG7
PhylomeDBiQ5SZD1
TreeFamiTF336881

Miscellaneous databases

GenomeRNAii135398
PROiPR:Q5SZD1

Gene expression databases

BgeeiENSG00000197261 Expressed in 132 organ(s), highest expression level in caudate nucleus
CleanExiHS_C6orf141
ExpressionAtlasiQ5SZD1 baseline and differential
GenevisibleiQ5SZD1 HS

Family and domain databases

InterProiView protein in InterPro
IPR037739 C6orf141
PANTHERiPTHR36880 PTHR36880, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCF141_HUMAN
AccessioniPrimary (citable) accession number: Q5SZD1
Secondary accession number(s): A8K1H4, Q8N400, Q96NQ1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: January 11, 2011
Last modified: September 12, 2018
This is version 92 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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Main funding by: National Institutes of Health

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