UniProtKB - Q5SZB4 (CI050_HUMAN)
Protein
Uncharacterized protein C9orf50
Gene
C9orf50
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein C9orf50 |
Gene namesi | Name:C9orf50 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:23677, C9orf50 |
neXtProti | NX_Q5SZB4 |
VEuPathDBi | HostDB:ENSG00000179058.6 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000179058 |
PharmGKBi | PA142672314 |
Miscellaneous databases
Pharosi | Q5SZB4, Tdark |
Genetic variation databases
BioMutai | C9orf50 |
DMDMi | 74744124 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000295144 | 1 – 431 | Uncharacterized protein C9orf50Add BLAST | 431 |
Proteomic databases
PaxDbi | Q5SZB4 |
PeptideAtlasi | Q5SZB4 |
PRIDEi | Q5SZB4 |
ProteomicsDBi | 64049 |
PTM databases
iPTMneti | Q5SZB4 |
PhosphoSitePlusi | Q5SZB4 |
Expressioni
Gene expression databases
Bgeei | ENSG00000179058, Expressed in left testis and 92 other tissues |
ExpressionAtlasi | Q5SZB4, baseline and differential |
Genevisiblei | Q5SZB4, HS |
Organism-specific databases
HPAi | ENSG00000179058, Tissue enhanced (testis) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 131998, 2 interactors |
IntActi | Q5SZB4, 1 interactor |
STRINGi | 9606.ENSP00000361556 |
Miscellaneous databases
RNActi | Q5SZB4, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502TKNG, Eukaryota |
GeneTreei | ENSGT00390000004321 |
HOGENOMi | CLU_052521_1_0_1 |
InParanoidi | Q5SZB4 |
OMAi | ANHRPHG |
OrthoDBi | 1120902at2759 |
PhylomeDBi | Q5SZB4 |
TreeFami | TF338486 |
Family and domain databases
InterProi | View protein in InterPro IPR032756, DUF4685 |
Pfami | View protein in Pfam PF15737, DUF4685, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q5SZB4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFWRRLRPGA QDLAPKGLPG DGDFRRSSDP RLPKLTPPAL RAALGARGSG
60 70 80 90 100
DWRIPGGGAA WWPEGDAKPG VGVGRLPPRL PALLTATRRA VRKRGLLRSL
110 120 130 140 150
LPPPLLSAGA SRESAPRQPG PGERERPRRR VAREDPDFLG AFLGELLPSR
160 170 180 190 200
FREFLHQLQE KCAEEPEPLT SPAPQHQRGV LEHCPGSPRC PNCSFLPDLW
210 220 230 240 250
GQSSHLQDSL TKISLQQTPI LGPLKGDHSQ FTTVRKANHR PHGAQVPRLK
260 270 280 290 300
AALTHNPSGE GSRPCRQRCP FRVRFADETL QDTTLRYWER RRSVQQSVIV
310 320 330 340 350
NQKAALPVAS ERVFGSVGKR LESLPKALYP GAKEETLASS SCWDCAGLST
360 370 380 390 400
QKTQGYLSED TSMNSSLPFC SWKKAAAQRP RSSLRAFLDP HRNLEQESLL
410 420 430
PNRVLQSVLK QGCPKGYHLL LASATLQPDK R
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A087WX76 | A0A087WX76_HUMAN | Chromosome 9 open reading frame 50,... | C9orf50 hCG_30607 | 69 | Annotation score: |
Sequence cautioni
The sequence AK093122 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 163 | A → T in AK093122 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 368 | P → S in AAI12354 (PubMed:15489334).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_033220 | 248 | R → K. Corresponds to variant dbSNP:rs918165Ensembl. | 1 | |
Natural variantiVAR_033221 | 312 | R → Q. Corresponds to variant dbSNP:rs3213763Ensembl. | 1 | |
Natural variantiVAR_033222 | 381 | R → Q. Corresponds to variant dbSNP:rs2302779Ensembl. | 1 | |
Natural variantiVAR_033223 | 415 | K → R. Corresponds to variant dbSNP:rs3087721Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK093122 mRNA No translation available. AL590369 Genomic DNA No translation available. AL391056 Genomic DNA No translation available. BC112353 mRNA Translation: AAI12354.1 |
CCDSi | CCDS35159.1 |
RefSeqi | NP_955382.3, NM_199350.3 XP_011516957.1, XM_011518655.1 XP_011516958.1, XM_011518656.1 |
Genome annotation databases
Ensembli | ENST00000372478; ENSP00000361556; ENSG00000179058 |
GeneIDi | 375759 |
KEGGi | hsa:375759 |
UCSCi | uc004byc.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK093122 mRNA No translation available. AL590369 Genomic DNA No translation available. AL391056 Genomic DNA No translation available. BC112353 mRNA Translation: AAI12354.1 |
CCDSi | CCDS35159.1 |
RefSeqi | NP_955382.3, NM_199350.3 XP_011516957.1, XM_011518655.1 XP_011516958.1, XM_011518656.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 131998, 2 interactors |
IntActi | Q5SZB4, 1 interactor |
STRINGi | 9606.ENSP00000361556 |
PTM databases
iPTMneti | Q5SZB4 |
PhosphoSitePlusi | Q5SZB4 |
Genetic variation databases
BioMutai | C9orf50 |
DMDMi | 74744124 |
Proteomic databases
PaxDbi | Q5SZB4 |
PeptideAtlasi | Q5SZB4 |
PRIDEi | Q5SZB4 |
ProteomicsDBi | 64049 |
Protocols and materials databases
Antibodypediai | 17886, 39 antibodies |
Genome annotation databases
Ensembli | ENST00000372478; ENSP00000361556; ENSG00000179058 |
GeneIDi | 375759 |
KEGGi | hsa:375759 |
UCSCi | uc004byc.4, human |
Organism-specific databases
CTDi | 375759 |
GeneCardsi | C9orf50 |
HGNCi | HGNC:23677, C9orf50 |
HPAi | ENSG00000179058, Tissue enhanced (testis) |
neXtProti | NX_Q5SZB4 |
OpenTargetsi | ENSG00000179058 |
PharmGKBi | PA142672314 |
VEuPathDBi | HostDB:ENSG00000179058.6 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502TKNG, Eukaryota |
GeneTreei | ENSGT00390000004321 |
HOGENOMi | CLU_052521_1_0_1 |
InParanoidi | Q5SZB4 |
OMAi | ANHRPHG |
OrthoDBi | 1120902at2759 |
PhylomeDBi | Q5SZB4 |
TreeFami | TF338486 |
Enzyme and pathway databases
PathwayCommonsi | Q5SZB4 |
Miscellaneous databases
BioGRID-ORCSi | 375759, 7 hits in 979 CRISPR screens |
GenomeRNAii | 375759 |
Pharosi | Q5SZB4, Tdark |
PROi | PR:Q5SZB4 |
RNActi | Q5SZB4, protein |
Gene expression databases
Bgeei | ENSG00000179058, Expressed in left testis and 92 other tissues |
ExpressionAtlasi | Q5SZB4, baseline and differential |
Genevisiblei | Q5SZB4, HS |
Family and domain databases
InterProi | View protein in InterPro IPR032756, DUF4685 |
Pfami | View protein in Pfam PF15737, DUF4685, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CI050_HUMAN | |
Accessioni | Q5SZB4Primary (citable) accession number: Q5SZB4 Secondary accession number(s): Q2M1I2, Q8NA65 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 10, 2007 |
Last sequence update: | December 21, 2004 | |
Last modified: | April 7, 2021 | |
This is version 98 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports