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Protein
Submitted name:

Tripartite motif-containing 38

Gene

Trim38

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Tripartite motif-containing 38Imported
Gene namesi
Name:Trim38Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2684869 Trim38

Subcellular locationi

PTM / Processingi

PTM databases

iPTMnetiQ5SZ99
PhosphoSitePlusiQ5SZ99

Expressioni

Gene expression databases

BgeeiENSMUSG00000064140 Expressed in 14 organ(s), highest expression level in colon

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073709

Structurei

3D structure databases

ProteinModelPortaliQ5SZ99
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 62RING-typeInterPro annotationAdd BLAST47
Domaini90 – 131B box-typeInterPro annotationAdd BLAST42
Domaini276 – 471B30.2/SPRYInterPro annotationAdd BLAST196

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili135 – 159Sequence analysisAdd BLAST25
Coiled coili211 – 263Sequence analysisAdd BLAST53

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
GeneTreeiENSGT00760000118893
HOVERGENiHBG001357
InParanoidiQ5SZ99
KOiK12014
OMAiPDTAHHE
OrthoDBiEOG091G05W2
PhylomeDBiQ5SZ99
TreeFamiTF342569

Family and domain databases

CDDicd00021 BBOX, 1 hit
cd15815 SPRY_PRY_TRIM38, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR006574 PRY
IPR035790 SPRY/PRY_TRIM38
IPR003877 SPRY_dom
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF13765 PRY, 1 hit
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00589 PRY, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5SZ99-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSDFSTVKI RKVTSCSICK AMMSHPVSIN CGHSYCKSCI QSYYCNVSPK
60 70 80 90 100
TGWKMLGCPL CSSPFSLENL RPNKELETII DMIKGMEEQD QDMVCEEHEE
110 120 130 140 150
KFNRFCEDDG QLLCWRCYWE DRHKGHTLAH VKDVYQNYKE KLQNTMTKLR
160 170 180 190 200
ELQENHEVQI HFITHQINAW KDAVEDRRQT IKSNFKNLQS FLQEEEKFYL
210 220 230 240 250
WRLENEEKEM LVQLEGSEAN LQQTFERAQC QIQELEAKCQ GSAQKLLQDV
260 270 280 290 300
KNTLSRCEAM KRNPLKADPL KVHTKCNVSE LYFDVKTILR RHQVSVILDP
310 320 330 340 350
STAHLDLALT KGGRLVTYKR CPRDLQARSS AKRFYGLPCV LGCEGFTSGR
360 370 380 390 400
YYFEVSVENA TSWDLGVCVE NVHRGFNMKK EPESGFWTIK MSEEDGLEAL
410 420 430 440 450
TSTPTPPLHL IEKPQILGVF LDYEAGAVSF YSVTTGSHIF TFPKASFQDT
460 470
LRPFFQVYQY SPLFLPAINN Q
Length:471
Mass (Da):54,430
Last modified:December 21, 2004 - v1
Checksum:i9C4BE6BACFAD6540
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286YDR5A0A286YDR5_MOUSE
Tripartite motif-containing 38
Trim38
249Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590388 Genomic DNA No translation available.
RefSeqiNP_001025106.1, NM_001029935.2
XP_006516700.1, XM_006516637.2
XP_011242605.1, XM_011244303.1
UniGeneiMm.314151

Genome annotation databases

EnsembliENSMUST00000074067; ENSMUSP00000073709; ENSMUSG00000064140
ENSMUST00000226039; ENSMUSP00000153240; ENSMUSG00000064140
GeneIDi214158
KEGGimmu:214158
UCSCiuc007pva.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590388 Genomic DNA No translation available.
RefSeqiNP_001025106.1, NM_001029935.2
XP_006516700.1, XM_006516637.2
XP_011242605.1, XM_011244303.1
UniGeneiMm.314151

3D structure databases

ProteinModelPortaliQ5SZ99
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073709

PTM databases

iPTMnetiQ5SZ99
PhosphoSitePlusiQ5SZ99

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000074067; ENSMUSP00000073709; ENSMUSG00000064140
ENSMUST00000226039; ENSMUSP00000153240; ENSMUSG00000064140
GeneIDi214158
KEGGimmu:214158
UCSCiuc007pva.2 mouse

Organism-specific databases

CTDi10475
MGIiMGI:2684869 Trim38

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
GeneTreeiENSGT00760000118893
HOVERGENiHBG001357
InParanoidiQ5SZ99
KOiK12014
OMAiPDTAHHE
OrthoDBiEOG091G05W2
PhylomeDBiQ5SZ99
TreeFamiTF342569

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000064140 Expressed in 14 organ(s), highest expression level in colon

Family and domain databases

CDDicd00021 BBOX, 1 hit
cd15815 SPRY_PRY_TRIM38, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR006574 PRY
IPR035790 SPRY/PRY_TRIM38
IPR003877 SPRY_dom
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF13765 PRY, 1 hit
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00589 PRY, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SZ99_MOUSE
AccessioniPrimary (citable) accession number: Q5SZ99
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: October 10, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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