UniProtKB - Q5SWZ0 (Q5SWZ0_MOUSE)
Protein
Submitted name:
Prpsap2 protein
Gene
Prpsap2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- identical protein binding Source: Ensembl
- magnesium ion binding Source: InterPro
- ribose phosphate diphosphokinase activity Source: InterPro
GO - Biological processi
- nucleoside metabolic process Source: InterPro
- nucleotide biosynthetic process Source: UniProtKB-KW
Keywordsi
Biological process | Nucleotide biosynthesisARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Prpsap2 proteinImported |
Gene namesi | Name:Prpsap2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:2384838, Prpsap2 |
Subcellular locationi
Other locations
- ribose phosphate diphosphokinase complex Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000020528, Expressed in secondary oocyte and 67 other tissues |
ExpressionAtlasi | Q5SWZ0, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 28 – 138 | Pribosyltran_NInterPro annotationAdd BLAST | 111 |
Sequence similaritiesi
Belongs to the ribose-phosphate pyrophosphokinase family.ARBA annotation
Phylogenomic databases
HOGENOMi | CLU_033546_0_0_1 |
OMAi | HYAYARS |
OrthoDBi | 1043963at2759 |
Family and domain databases
CDDi | cd06223, PRTases_typeI, 1 hit |
InterProi | View protein in InterPro IPR029099, Pribosyltran_N IPR000836, PRibTrfase_dom IPR029057, PRTase-like IPR005946, Rib-P_diPkinase |
PANTHERi | PTHR10210, PTHR10210, 1 hit |
Pfami | View protein in Pfam PF14572, Pribosyl_synth, 1 hit PF13793, Pribosyltran_N, 1 hit |
SUPFAMi | SSF53271, SSF53271, 2 hits |
TIGRFAMsi | TIGR01251, ribP_PPkin, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5SWZ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFCVAPPELE TKMNITKGGL VLFSANSNSS CMELSKKIAE RLGVEMGKVQ
60 70 80 90 100
VYQEPNRETR VQIQESVRGK DVFIIQTISK DVNTTIMELL IMVYACKTSC
110 120 130 140 150
AKSIIGVIPY FPYSKQCKMR KRGSIVSKLL ASMMCKAGLT HLITMDLHQK
160 170 180 190 200
EIQGFFNIPV DNLRASPFLL QYIQEEIPDY RNAVIVAKSP ASAKRAQSFA
210 220 230 240 250
ERLRLGIAVI HGEAQDAESD LVDGRHSPPM VRSVAAIHPS LEIPMLIPKE
260 270 280 290 300
KPPITVVGDV GGRIAIIVDD IIDDVDSFLA AAETLKERGA YKIFVMATHG
310 320 330 340 350
LLSSDAPRLI EESAIDEVVV TNTIPHEIQK LQCPKIKTVD ISMILSEAIR
360
RIHNGESMSY LFRNIGLDD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC106185 mRNA Translation: AAI06186.1 AK038680 mRNA Translation: BAC30096.1 |
RefSeqi | NP_001157714.1, NM_001164242.1 NP_001157715.1, NM_001164243.1 NP_001157716.1, NM_001164244.1 NP_659055.1, NM_144806.2 XP_006532824.1, XM_006532761.3 |
Genome annotation databases
GeneIDi | 212627 |
KEGGi | mmu:212627 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC106185 mRNA Translation: AAI06186.1 AK038680 mRNA Translation: BAC30096.1 |
RefSeqi | NP_001157714.1, NM_001164242.1 NP_001157715.1, NM_001164243.1 NP_001157716.1, NM_001164244.1 NP_659055.1, NM_144806.2 XP_006532824.1, XM_006532761.3 |
3D structure databases
SMRi | Q5SWZ0 |
ModBasei | Search... |
PTM databases
SwissPalmi | Q5SWZ0 |
Proteomic databases
EPDi | Q5SWZ0 |
PeptideAtlasi | Q5SWZ0 |
Protocols and materials databases
Antibodypediai | 13570, 142 antibodies |
Genome annotation databases
GeneIDi | 212627 |
KEGGi | mmu:212627 |
Organism-specific databases
CTDi | 5636 |
MGIi | MGI:2384838, Prpsap2 |
Phylogenomic databases
HOGENOMi | CLU_033546_0_0_1 |
OMAi | HYAYARS |
OrthoDBi | 1043963at2759 |
Miscellaneous databases
BioGRID-ORCSi | 212627, 1 hit in 17 CRISPR screens |
ChiTaRSi | Prpsap2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000020528, Expressed in secondary oocyte and 67 other tissues |
ExpressionAtlasi | Q5SWZ0, baseline and differential |
Family and domain databases
CDDi | cd06223, PRTases_typeI, 1 hit |
InterProi | View protein in InterPro IPR029099, Pribosyltran_N IPR000836, PRibTrfase_dom IPR029057, PRTase-like IPR005946, Rib-P_diPkinase |
PANTHERi | PTHR10210, PTHR10210, 1 hit |
Pfami | View protein in Pfam PF14572, Pribosyl_synth, 1 hit PF13793, Pribosyltran_N, 1 hit |
SUPFAMi | SSF53271, SSF53271, 2 hits |
TIGRFAMsi | TIGR01251, ribP_PPkin, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5SWZ0_MOUSE | |
Accessioni | Q5SWZ0Primary (citable) accession number: Q5SWZ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | December 2, 2020 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |