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Entry version 107 (07 Oct 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Uncharacterized protein C10orf55

Gene

C10orf55

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q5SWW7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C10orf55
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000222047.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:31008, C10orf55

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5SWW7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000222047

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134866694

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5SWW7, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C10orf55

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000897951 – 151Uncharacterized protein C10orf55Add BLAST151

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5SWW7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5SWW7

PRoteomics IDEntifications database

More...
PRIDEi
Q5SWW7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
63979

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000222047, Expressed in sperm and 70 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5SWW7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000222047, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q5SWW7
With#Exp.IntAct
ATXN1 [P54253]3EBI-12809220,EBI-930964
BOLA2B [A0A087WZT3]3EBI-12809220,EBI-12006120
itself3EBI-12809220,EBI-12809220
CRYBA2 [P53672]3EBI-12809220,EBI-750444
DTX2 [Q86UW9]3EBI-12809220,EBI-740376
FAM168A - isoform 2 [Q92567-2]3EBI-12809220,EBI-11978259
FAM222B [Q8WU58]3EBI-12809220,EBI-2807642
FNDC3B - isoform 3 [Q53EP0-3]3EBI-12809220,EBI-10242151
FOXH1 [O75593]3EBI-12809220,EBI-1759806
GCA [P28676]3EBI-12809220,EBI-947242
HNF1B [P35680]3EBI-12809220,EBI-2798841
HNRNPF [P52597]3EBI-12809220,EBI-352986
HSF4 - isoform HSF4A [Q9ULV5-2]3EBI-12809220,EBI-12056251
INCA1 [Q0VD86]3EBI-12809220,EBI-6509505
KRTAP15-1 [Q3LI76]3EBI-12809220,EBI-11992140
KRTAP6-2 [Q3LI66]3EBI-12809220,EBI-11962084
LENG8 [Q96PV6]3EBI-12809220,EBI-739546
LIMS4 [P0CW20]3EBI-12809220,EBI-10196832
MYOZ3 [Q8TDC0]3EBI-12809220,EBI-5662487
NRF1 - isoform 4 [Q16656-4]3EBI-12809220,EBI-11742836
NXF1 [Q9UBU9]3EBI-12809220,EBI-398874
OTX1 [P32242]3EBI-12809220,EBI-740446
PFDN5 [Q99471]3EBI-12809220,EBI-357275
PITX1 [P78337]3EBI-12809220,EBI-748265
PLEKHB1 - isoform 2 [Q9UF11-2]4EBI-12809220,EBI-12832742
PLSCR3 [Q9NRY6]3EBI-12809220,EBI-750734
POGZ [Q7Z3K3]5EBI-12809220,EBI-1389308
PPP1R32 - isoform 2 [Q7Z5V6-2]3EBI-12809220,EBI-12000762
PRR20D [P86480]3EBI-12809220,EBI-12754095
RAMAC [Q9BTL3]3EBI-12809220,EBI-744023
RBM24 - isoform 2 [Q9BX46-2]3EBI-12809220,EBI-12224445
RBM47 [A0AV96]3EBI-12809220,EBI-2823850
RBPMS - isoform C [Q93062-3]3EBI-12809220,EBI-740343
RBPMS2 [Q6ZRY4]3EBI-12809220,EBI-11987469
ROR2 [Q01974]3EBI-12809220,EBI-6422642
SMUG1 - isoform 2 [Q53HV7-2]3EBI-12809220,EBI-12275818
SNRPB - isoform SM-B [P14678-2]3EBI-12809220,EBI-372475
SOHLH1 [Q5JUK2]3EBI-12809220,EBI-12288855
SOX10 [P56693]3EBI-12809220,EBI-1167533
TBX6 [O95947]3EBI-12809220,EBI-2824328
TENT5B [Q96A09]5EBI-12809220,EBI-752030
TENT5D [Q8NEK8]3EBI-12809220,EBI-744726
TIAL1 - isoform 2 [Q01085-2]3EBI-12809220,EBI-11064654
TLE5 - isoform 2 [Q08117-2]3EBI-12809220,EBI-11741437
TP53BP1 [Q12888]3EBI-12809220,EBI-396540
UBAP2 [Q5T6F2]3EBI-12809220,EBI-2514383
UFSP1 [Q6NVU6]3EBI-12809220,EBI-12068150
VENTX [O95231]3EBI-12809220,EBI-10191303
VEZF1 [Q14119]5EBI-12809220,EBI-11980193
WWOX - isoform 5 [Q9NZC7-5]3EBI-12809220,EBI-12040603
ZC3H10 [Q96K80]3EBI-12809220,EBI-742550
ZNF76 [P36508]3EBI-12809220,EBI-7254550

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
136015, 64 interactors

Protein interaction database and analysis system

More...
IntActi
Q5SWW7, 53 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000409225

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5SWW7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5SWW7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RKN2, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017469

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_1730802_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5SWW7

Identification of Orthologs from Complete Genome Data

More...
OMAi
EVHGCPG

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5SWW7

TreeFam database of animal gene trees

More...
TreeFami
TF340698

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5SWW7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFLHLDSHSS LERTKPTVVG VDTHMELDEV HCCPGRDSGG GFIKGPMLQG
60 70 80 90 100
LQGEGKLAPI PKPTLPSPSR LTLFVSSSQM EDHGFPARRN GLTQASFIYQ
110 120 130 140 150
MPAGWGSPGG LFLPCQPVPT PVVLKPPLPP CPISWGESGP AVDGIRRTPA

P
Length:151
Mass (Da):16,057
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i94886D74E7460202
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC03908 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL596247 Genomic DNA No translation available.
BC049374 mRNA Translation: AAH49374.1
AK092517 mRNA Translation: BAC03908.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_001001791.2, NM_001001791.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000412307; ENSP00000409225; ENSG00000222047

UCSC genome browser

More...
UCSCi
uc057ueo.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596247 Genomic DNA No translation available.
BC049374 mRNA Translation: AAH49374.1
AK092517 mRNA Translation: BAC03908.1 Different initiation.
RefSeqiNP_001001791.2, NM_001001791.2

3D structure databases

SMRiQ5SWW7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi136015, 64 interactors
IntActiQ5SWW7, 53 interactors
STRINGi9606.ENSP00000409225

Polymorphism and mutation databases

BioMutaiC10orf55

Proteomic databases

jPOSTiQ5SWW7
PaxDbiQ5SWW7
PRIDEiQ5SWW7
ProteomicsDBi63979

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
49038, 17 antibodies

Genome annotation databases

EnsembliENST00000412307; ENSP00000409225; ENSG00000222047
UCSCiuc057ueo.1, human

Organism-specific databases

EuPathDBiHostDB:ENSG00000222047.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C10orf55
HGNCiHGNC:31008, C10orf55
HPAiENSG00000222047, Tissue enriched (testis)
neXtProtiNX_Q5SWW7
OpenTargetsiENSG00000222047
PharmGKBiPA134866694

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RKN2, Eukaryota
GeneTreeiENSGT00390000017469
HOGENOMiCLU_1730802_0_0_1
InParanoidiQ5SWW7
OMAiEVHGCPG
PhylomeDBiQ5SWW7
TreeFamiTF340698

Enzyme and pathway databases

PathwayCommonsiQ5SWW7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
414236, 5 hits in 859 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C10orf55, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
414236
PharosiQ5SWW7, Tdark

Protein Ontology

More...
PROi
PR:Q5SWW7
RNActiQ5SWW7, protein

Gene expression databases

BgeeiENSG00000222047, Expressed in sperm and 70 other tissues
GenevisibleiQ5SWW7, HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCJ055_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SWW7
Secondary accession number(s): Q3KRG4, Q8NAK4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 21, 2004
Last modified: October 7, 2020
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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