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Entry version 133 (07 Oct 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Mediator of RNA polymerase II transcription subunit 13

Gene

Med13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mediator of RNA polymerase II transcription subunit 13
Alternative name(s):
Thyroid hormone receptor-associated protein 1
Thyroid hormone receptor-associated protein complex 240 kDa component
Short name:
Trap240
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Med13
Synonyms:Kiaa0593, Thrap1, Trap240
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3029632, Med13

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003142401 – 2171Mediator of RNA polymerase II transcription subunit 13Add BLAST2171

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei395PhosphoserineBy similarity1
Modified residuei500PhosphoserineBy similarity1
Modified residuei504PhosphoserineBy similarity1
Modified residuei530PhosphoserineCombined sources1
Modified residuei537PhosphoserineCombined sources1
Modified residuei825PhosphoserineBy similarity1
Modified residuei889PhosphoserineBy similarity1
Modified residuei1028PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5SWW4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5SWW4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5SWW4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5SWW4

PeptideAtlas

More...
PeptideAtlasi
Q5SWW4

PRoteomics IDEntifications database

More...
PRIDEi
Q5SWW4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5SWW4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5SWW4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000034297, Expressed in pineal body and 251 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5SWW4, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
236522, 4 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-3266, CKM complex variant 1
CPX-3267, CKM complex variant 2

Database of interacting proteins

More...
DIPi
DIP-61082N

Protein interaction database and analysis system

More...
IntActi
Q5SWW4, 4 interactors

Molecular INTeraction database

More...
MINTi
Q5SWW4

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000044268

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5SWW4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1187 – 1191LXXLL motif 15
Motifi1278 – 1282LXXLL motif 25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi448 – 451Poly-Gln4
Compositional biasi1507 – 1600Ser-richAdd BLAST94

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Mediator complex subunit 13 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3600, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013680

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000508_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5SWW4

KEGG Orthology (KO)

More...
KOi
K15164

Identification of Orthologs from Complete Genome Data

More...
OMAi
WWGEDPS

Database of Orthologous Groups

More...
OrthoDBi
177884at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5SWW4

TreeFam database of animal gene trees

More...
TreeFami
TF316867

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009401, Med13_C
IPR041285, MID_MedPIWI

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06333, Med13_C, 1 hit
PF18296, MID_MedPIWI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5SWW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSFVSNGA SLEDCHCNLF CLADLTGIKW KRYVWQGPTS APILFPVTEE
60 70 80 90 100
DPILSSFSRC LKADVLGVWR RDQRPGRREL WIFWWGKDPN FADLIHHDLS
110 120 130 140 150
EEEDGVWENG LSYECRTLLF KAVHNLLERC LMNRNFVRIG KWFVKPYEKD
160 170 180 190 200
EKPINKSEHL SCSFTFFLHG DSNVCTSVEI NQHQPVYLLS EEHVTLAQQS
210 220 230 240 250
NSPFQVILSP FGLNGTLTGQ AFKMSDSATK KLIGEWKQFY PISCGLKEMS
260 270 280 290 300
EEKQDDMDWE DDSLAAVEVL VAGVRMIYPA CFVLVPQSDI PAPSSVGASH
310 320 330 340 350
CSASCLGIHQ VPASTRDPAM SSVTLTPPTS PEEVQTVDPQ SAQKWVKFSS
360 370 380 390 400
VSDGFSTDST SHHGGKIPRK LANHVVDRVW QECNMNRLQN KRKYSATSSG
410 420 430 440 450
LCEEETADKI GCWDFVEATQ RTSCSCLRHK SLKTRNTGQQ GQAPSLGQQQ
460 470 480 490 500
QVLPKHKTNE KQDKSEKPQK RPLTPFHHRV SVSDEIGMDT DSASQRLVIS
510 520 530 540 550
AADSQVRFSN IRTNDVAKTP QMHGTELANS PQPPPLSPHP CDVVDEGVTK
560 570 580 590 600
TPSTPQSQHF YQMPTPDPLV PTKPMEDRID SLSQSFPPPF QEAVEPTVYV
610 620 630 640 650
GTAVSLEEDE ANVAWKYYKV PKKKDVEFLP PQLPNDKFKD DPVGPFGQES
660 670 680 690 700
VTSVTELMVQ CKKPLKVSDE IVQQYQIKNQ YLSAIASDTE QEPKIDPYAF
710 720 730 740 750
VEGDEEFIFT DKKDRQNSER EAGKKHKVED GTSAVTVLSH EEDAMSLFSP
760 770 780 790 800
SKQDAPRPTN HARPPSTSLI YDSDLAVSYT DLDNLFNSDE DELTPGSKKS
810 820 830 840 850
ASGSDDKASS KESKTGNLDP LSCISTADLH KMYPTPPSLE QHIMGFSPMN
860 870 880 890 900
MNNKEYGSVD TAPGGTVLEG NSSSVGTQFR IEVEEGFCSP KPSEIKDFSY
910 920 930 940 950
VYKPENCQVL VGCSMFAPLK TLPSHCLPPI KLPEECVYRQ SWTVGKLDLL
960 970 980 990 1000
PSGPSMPFIK EGDGSNLDQD YGPAYTPQTH ASFGMPPSSA PPSNGGAGIL
1010 1020 1030 1040 1050
PSPSTPRFPT PRTPRTPRTP RGAGGPASAQ GSVKYENSDL YSPASTPSTC
1060 1070 1080 1090 1100
RPLNSVEPAT VPSIPEAHSL YVNLILSESV MNLFKDCNFD SCCICVCNMN
1110 1120 1130 1140 1150
IKGADVGVYI PDPTQEAQYR CTCGFSAVMN RKFGNNSGLF LEDELDIIGR
1160 1170 1180 1190 1200
NTDCGKEAEK RFEALRASSV ENVNGGLKES EKVPDELILL LQDQCTNLFS
1210 1220 1230 1240 1250
PFGAADQDPF PKVGISSNWV RVEERDCCSD CCLALEHGRQ FMDNMSGGKV
1260 1270 1280 1290 1300
DEALVRSSCL HPWAKQNDAS VQCSQDILRM LLSLQPVLQD AIQKKRTVRP
1310 1320 1330 1340 1350
WGVQGPLTWQ QFHKMAGRGS YGTDESPEPL PIPTFLLGYD YDFLVLSPFA
1360 1370 1380 1390 1400
LPYWEKLMLE PYGSQRDIAY VVLCPENEAL LNGARSFFRD LTAIYESCRL
1410 1420 1430 1440 1450
GQHRPISRLL TDGIMKVGAT ASKKLSEKFV TEWFSQAADG NNEAFSKLKL
1460 1470 1480 1490 1500
YAQVCRYDLG PYLASQPLDS SLLSQPNLVA PPNQSLVTAP QMTNTGNANA
1510 1520 1530 1540 1550
PSATLASAAS STMTMTSGVP ISTSVATANS TLTTTSSSSS SSLSSGVSSN
1560 1570 1580 1590 1600
KLPSFPPFGS MNTSGTGSMS AQASTVQSGQ LGGQQSSSLQ AAGISGESAS
1610 1620 1630 1640 1650
LPTQPHPDVS ESTMDRDKVG IPTDGDSHAI TYPPAIVVYI IDPFTYENKD
1660 1670 1680 1690 1700
ESTNSSNVWT LGLLRCFLEM VQTLPPHIKS TVSVQIVPCQ YLLQPVKHDD
1710 1720 1730 1740 1750
RQIYSQHLKS LAFSVFTQCR RPLPTSTNVK TLTGFGPGLA METALKSPDR
1760 1770 1780 1790 1800
PECIRLYTPP FILAPVKDKQ TELGETFGEA GQKYNVLFVG YCLSHDQRWI
1810 1820 1830 1840 1850
LASCTDLYGE LLETCIINID VPNRARRKKG SARRFGLQKL WEWCLGLVQM
1860 1870 1880 1890 1900
SSLPWRVVIG RLGRIGHGEL KDWSCLLSRR NLQSLSKRLK DMCRMCGISA
1910 1920 1930 1940 1950
ADSPSILSAC LVAMEPQGSF VIMPDSVSTG SVFGRSTTLN MQTPQLNTPQ
1960 1970 1980 1990 2000
DTSCTHILVF PTSASVQVAS ATYTTENLDL AFNPNNDGAD GMGIFDLLDT
2010 2020 2030 2040 2050
GDDLDPDIIN ILPASPTASP VHSPGSHYPH GGDAGKGQGT DRLLSTESHD
2060 2070 2080 2090 2100
EVTNILQQPL ALGYFVSTAK AGPLPDWFWS ACPQAQYQCP LFLKASLHLH
2110 2120 2130 2140 2150
VPSVQSDELL HSKHSHPLDS NQTSDVLRFV LEQYNALSWL TCDPAVQDRR
2160 2170
SCLPVHFVVL NQLYNFIMNM L
Length:2,171
Mass (Da):238,591
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFD54462F5DC387B9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1299 – 1322RPWGV…RGSYG → GTDESAVVPEIHQFHKSLGQ PFYE in BAC97978 (PubMed:14621295).CuratedAdd BLAST24

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL592065 Genomic DNA No translation available.
AL596256 Genomic DNA No translation available.
AK037303 mRNA Translation: BAE20510.1
AK129168 mRNA Translation: BAC97978.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS36267.1

NCBI Reference Sequences

More...
RefSeqi
NP_001074400.1, NM_001080931.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000043624; ENSMUSP00000044268; ENSMUSG00000034297

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
327987

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:327987

UCSC genome browser

More...
UCSCi
uc007ksk.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592065 Genomic DNA No translation available.
AL596256 Genomic DNA No translation available.
AK037303 mRNA Translation: BAE20510.1
AK129168 mRNA Translation: BAC97978.1
CCDSiCCDS36267.1
RefSeqiNP_001074400.1, NM_001080931.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi236522, 4 interactors
ComplexPortaliCPX-3266, CKM complex variant 1
CPX-3267, CKM complex variant 2
DIPiDIP-61082N
IntActiQ5SWW4, 4 interactors
MINTiQ5SWW4
STRINGi10090.ENSMUSP00000044268

PTM databases

iPTMnetiQ5SWW4
PhosphoSitePlusiQ5SWW4

Proteomic databases

EPDiQ5SWW4
jPOSTiQ5SWW4
MaxQBiQ5SWW4
PaxDbiQ5SWW4
PeptideAtlasiQ5SWW4
PRIDEiQ5SWW4

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31215, 69 antibodies

The DNASU plasmid repository

More...
DNASUi
327987

Genome annotation databases

EnsembliENSMUST00000043624; ENSMUSP00000044268; ENSMUSG00000034297
GeneIDi327987
KEGGimmu:327987
UCSCiuc007ksk.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9969
MGIiMGI:3029632, Med13

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG3600, Eukaryota
GeneTreeiENSGT00390000013680
HOGENOMiCLU_000508_0_0_1
InParanoidiQ5SWW4
KOiK15164
OMAiWWGEDPS
OrthoDBi177884at2759
PhylomeDBiQ5SWW4
TreeFamiTF316867

Enzyme and pathway databases

ReactomeiR-MMU-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
327987, 7 hits in 21 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Med13, mouse

Protein Ontology

More...
PROi
PR:Q5SWW4
RNActiQ5SWW4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000034297, Expressed in pineal body and 251 other tissues
GenevisibleiQ5SWW4, MM

Family and domain databases

InterProiView protein in InterPro
IPR009401, Med13_C
IPR041285, MID_MedPIWI
PfamiView protein in Pfam
PF06333, Med13_C, 1 hit
PF18296, MID_MedPIWI, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMED13_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SWW4
Secondary accession number(s): Q3V3P6, Q6ZQ90
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 21, 2004
Last modified: October 7, 2020
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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