UniProtKB - Q5SWT3 (S2535_MOUSE)
Protein
Solute carrier family 25 member 35
Gene
Slc25a35
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Solute carrier family 25 member 35 |
Gene namesi | Name:Slc25a35 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1919248, Slc25a35 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity; Multi-pass membrane protein By similarity
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
- mitochondrion Source: MGI
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 38 – 58 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 59 – 79 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 91 – 119 | Helical; Name=3Sequence analysisAdd BLAST | 29 | |
Transmembranei | 169 – 190 | Helical; Name=4Sequence analysisAdd BLAST | 22 | |
Transmembranei | 205 – 225 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 277 – 300 | Helical; Name=6Sequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000291795 | 1 – 300 | Solute carrier family 25 member 35Add BLAST | 300 |
Proteomic databases
EPDi | Q5SWT3 |
jPOSTi | Q5SWT3 |
MaxQBi | Q5SWT3 |
PaxDbi | Q5SWT3 |
PeptideAtlasi | Q5SWT3 |
PRIDEi | Q5SWT3 |
PTM databases
iPTMneti | Q5SWT3 |
PhosphoSitePlusi | Q5SWT3 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000018740, Expressed in brown adipose tissue and 178 other tissues |
ExpressionAtlasi | Q5SWT3, baseline and differential |
Genevisiblei | Q5SWT3, MM |
Interactioni
Protein-protein interaction databases
IntActi | Q5SWT3, 2 interactors |
MINTi | Q5SWT3 |
STRINGi | 10090.ENSMUSP00000099666 |
Miscellaneous databases
RNActi | Q5SWT3, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 1 – 90 | Solcar 1Add BLAST | 90 | |
Repeati | 100 – 193 | Solcar 2Add BLAST | 94 | |
Repeati | 203 – 294 | Solcar 3Add BLAST | 92 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0755, Eukaryota |
GeneTreei | ENSGT00940000160771 |
InParanoidi | Q5SWT3 |
OMAi | VMSRMYN |
OrthoDBi | 1013743at2759 |
PhylomeDBi | Q5SWT3 |
TreeFami | TF324506 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q5SWT3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFLMSGVAA CGACVFTNPL EVVKTRMQLQ GELQAPGTYQ RHYRNVFHAF
60 70 80 90 100
FTIGKVDGLA ALQKGLGPAL LYQFLMNGIR LGTYGLAESR GYLHTNEGTH
110 120 130 140 150
SPVRSAAAGA LAGVMGAYLG SPIYMVKTHL QAQAASEIAV GHQYKHQGMF
160 170 180 190 200
QALTEIGQKH GLVGLWRGAV GGLPRVVIGS STQLCTFSSI KDLLSQWEIF
210 220 230 240 250
PPQSWKVALA AAMVSGVAIV VAMTPFDVAS TRLYNQPTDT RGKGLMYRGI
260 270 280 290 300
LDALLQTART EGFFGMYKGI GASYFRLGPH TILSLFFWDQ LRSFYNTYAK
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0A0MQ70 | A0A0A0MQ70_MOUSE | Solute carrier family 25 member 35 | Slc25a35 | 296 | Annotation score: |
Sequence cautioni
The sequence AAH04569 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAI25535 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK007453 mRNA Translation: BAB25048.1 AK171131 mRNA Translation: BAE42267.1 AL603662 Genomic DNA Translation: CAI25535.1 Sequence problems. AL603662 Genomic DNA Translation: CAI25536.1 BC004569 mRNA Translation: AAH04569.1 Different initiation. BC019996 mRNA Translation: AAH19996.1 |
CCDSi | CCDS24874.1 |
RefSeqi | NP_082324.1, NM_028048.2 XP_006534336.1, XM_006534273.2 |
Genome annotation databases
Ensembli | ENSMUST00000102606; ENSMUSP00000099666; ENSMUSG00000018740 |
GeneIDi | 71998 |
KEGGi | mmu:71998 |
UCSCi | uc007jop.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK007453 mRNA Translation: BAB25048.1 AK171131 mRNA Translation: BAE42267.1 AL603662 Genomic DNA Translation: CAI25535.1 Sequence problems. AL603662 Genomic DNA Translation: CAI25536.1 BC004569 mRNA Translation: AAH04569.1 Different initiation. BC019996 mRNA Translation: AAH19996.1 |
CCDSi | CCDS24874.1 |
RefSeqi | NP_082324.1, NM_028048.2 XP_006534336.1, XM_006534273.2 |
3D structure databases
SMRi | Q5SWT3 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q5SWT3, 2 interactors |
MINTi | Q5SWT3 |
STRINGi | 10090.ENSMUSP00000099666 |
PTM databases
iPTMneti | Q5SWT3 |
PhosphoSitePlusi | Q5SWT3 |
Proteomic databases
EPDi | Q5SWT3 |
jPOSTi | Q5SWT3 |
MaxQBi | Q5SWT3 |
PaxDbi | Q5SWT3 |
PeptideAtlasi | Q5SWT3 |
PRIDEi | Q5SWT3 |
Protocols and materials databases
Antibodypediai | 24621, 63 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000102606; ENSMUSP00000099666; ENSMUSG00000018740 |
GeneIDi | 71998 |
KEGGi | mmu:71998 |
UCSCi | uc007jop.1, mouse |
Organism-specific databases
CTDi | 399512 |
MGIi | MGI:1919248, Slc25a35 |
Phylogenomic databases
eggNOGi | KOG0755, Eukaryota |
GeneTreei | ENSGT00940000160771 |
InParanoidi | Q5SWT3 |
OMAi | VMSRMYN |
OrthoDBi | 1013743at2759 |
PhylomeDBi | Q5SWT3 |
TreeFami | TF324506 |
Miscellaneous databases
BioGRID-ORCSi | 71998, 1 hit in 17 CRISPR screens |
ChiTaRSi | Slc25a35, mouse |
PROi | PR:Q5SWT3 |
RNActi | Q5SWT3, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000018740, Expressed in brown adipose tissue and 178 other tissues |
ExpressionAtlasi | Q5SWT3, baseline and differential |
Genevisiblei | Q5SWT3, MM |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | S2535_MOUSE | |
Accessioni | Q5SWT3Primary (citable) accession number: Q5SWT3 Secondary accession number(s): Q3TBP2, Q99KM5, Q9D913 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2007 |
Last sequence update: | June 26, 2007 | |
Last modified: | February 10, 2021 | |
This is version 110 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families