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Protein
Submitted name:

Lactoperoxidase

Gene

Lpo

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • heme binding Source: InterPro
  • peroxidase activity Source: MGI
  • thiocyanate peroxidase activity Source: MGI

GO - Biological processi

Protein family/group databases

PeroxiBasei3343 MmLPO

Names & Taxonomyi

Protein namesi
Submitted name:
LactoperoxidaseImported
Gene namesi
Name:LpoImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1923363 Lpo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500426189724 – 710Sequence analysisAdd BLAST687

Proteomic databases

MaxQBiQ5SW46
PaxDbiQ5SW46
PRIDEiQ5SW46

PTM databases

iPTMnetiQ5SW46
PhosphoSitePlusiQ5SW46

Expressioni

Gene expression databases

BgeeiENSMUSG00000009356 Expressed in 59 organ(s), highest expression level in parotid gland
ExpressionAtlasiQ5SW46 baseline and differential
GenevisibleiQ5SW46 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099466

Structurei

3D structure databases

ProteinModelPortaliQ5SW46
SMRiQ5SW46
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2408 Eukaryota
ENOG410XPZ3 LUCA
GeneTreeiENSGT00550000074325
HOGENOMiHOG000016084
HOVERGENiHBG000071
InParanoidiQ5SW46
KOiK12550
OMAiFTEKQRD
OrthoDBiEOG091G0236
PhylomeDBiQ5SW46
TreeFamiTF314316

Family and domain databases

Gene3Di1.10.640.10, 1 hit
InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR019791 Haem_peroxidase_animal
IPR037120 Haem_peroxidase_sf
IPR029587 LPO
PANTHERiPTHR11475:SF67 PTHR11475:SF67, 1 hit
PfamiView protein in Pfam
PF03098 An_peroxidase, 1 hit
PRINTSiPR00457 ANPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS50292 PEROXIDASE_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5SW46-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKVLLHLPAL LASLTLLQTA ASASDDPTAE TDIIHDTVEE VKVWVNKAFL
60 70 80 90 100
DSRDRLKMAM TTKIHSTRHL SDYLKHAKGR TRTAIRSGQV WEESLKKLSQ
110 120 130 140 150
FLTNVTGQGL DLTLLSWEAG CDPPAPTMTC NISSPYRTIT GYCNNRKNPA
160 170 180 190 200
LGSANRALAR WLPAEYEDGL SLPYGWTPGK MRNGFPLPQP REVSNQIAAY
210 220 230 240 250
LNEEDVLDQK RSMLFMQWGQ IVDHDMDFAP ETEMGSDTYT KAQCDEHCIQ
260 270 280 290 300
GDNCFPIMFP PGDPKLKTQG KCMPFFRAGF VCPTPPYKSL AREQINALTS
310 320 330 340 350
FLDASLVYSP EPSLANRLRN LSSPLGLMAV NEEVSDNGRP FPPFVKMKPS
360 370 380 390 400
PCEVINATAG VPCFLAGDSR ASEQILLATS HTLFIREHNR LATELSRLNP
410 420 430 440 450
HWDRETLYQE ARKIMGAFIQ ITTFRDYLPI LLGDEMQKWI PPYQGYNESV
460 470 480 490 500
DPRISNVFTF ALRFGHLEIP STVYRLDENY QPWGSESELP LHTVFFNTWR
510 520 530 540 550
LVKDGGIDPL VRGLLAKNAK LMHQNKMMTG ELRNKLFQPN HTIHGFDLAS
560 570 580 590 600
INIQRSRDHG QPGYNSWRAF CGLSQPKTLE ELSAVMKNEV LAKKLMDLYG
610 620 630 640 650
TPSNIDIWLG AVAEPLVHRG RVGPLLTCLL GQQFQRIRDG DRFWWENPGV
660 670 680 690 700
FTEKQRESLQ KMSFSRLVCD NTGIDKVPLN PFQANAYPHG FVDCSSIDKL
710
DLSPWASVKE
Length:710
Mass (Da):80,124
Last modified:December 21, 2004 - v1
Checksum:i53D49184910601AE
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A7M7R7A7M7R7_MOUSE
Lactoperoxidase
Lpo
145Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL604022 Genomic DNA No translation available.
AL606805 Genomic DNA No translation available.
RefSeqiNP_536345.2, NM_080420.2
XP_011247600.1, XM_011249298.2
UniGeneiMm.41236

Genome annotation databases

EnsembliENSMUST00000103177; ENSMUSP00000099466; ENSMUSG00000009356
GeneIDi76113
KEGGimmu:76113
UCSCiuc007kus.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL604022 Genomic DNA No translation available.
AL606805 Genomic DNA No translation available.
RefSeqiNP_536345.2, NM_080420.2
XP_011247600.1, XM_011249298.2
UniGeneiMm.41236

3D structure databases

ProteinModelPortaliQ5SW46
SMRiQ5SW46
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099466

Protein family/group databases

PeroxiBasei3343 MmLPO

PTM databases

iPTMnetiQ5SW46
PhosphoSitePlusiQ5SW46

Proteomic databases

MaxQBiQ5SW46
PaxDbiQ5SW46
PRIDEiQ5SW46

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000103177; ENSMUSP00000099466; ENSMUSG00000009356
GeneIDi76113
KEGGimmu:76113
UCSCiuc007kus.2 mouse

Organism-specific databases

CTDi4025
MGIiMGI:1923363 Lpo

Phylogenomic databases

eggNOGiKOG2408 Eukaryota
ENOG410XPZ3 LUCA
GeneTreeiENSGT00550000074325
HOGENOMiHOG000016084
HOVERGENiHBG000071
InParanoidiQ5SW46
KOiK12550
OMAiFTEKQRD
OrthoDBiEOG091G0236
PhylomeDBiQ5SW46
TreeFamiTF314316

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000009356 Expressed in 59 organ(s), highest expression level in parotid gland
ExpressionAtlasiQ5SW46 baseline and differential
GenevisibleiQ5SW46 MM

Family and domain databases

Gene3Di1.10.640.10, 1 hit
InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR019791 Haem_peroxidase_animal
IPR037120 Haem_peroxidase_sf
IPR029587 LPO
PANTHERiPTHR11475:SF67 PTHR11475:SF67, 1 hit
PfamiView protein in Pfam
PF03098 An_peroxidase, 1 hit
PRINTSiPR00457 ANPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS50292 PEROXIDASE_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SW46_MOUSE
AccessioniPrimary (citable) accession number: Q5SW46
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 7, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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