Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q5SW19 (CLU_MOUSE)

Entry version 120 (12 Aug 2020)
Sequence version 2 (24 Mar 2009)
Previous versions | rss
Add a publicationFeedback
Protein

Clustered mitochondria protein homolog

Gene

Cluh

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Clustered mitochondria protein homologUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cluh
Synonyms:Kiaa0664
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1921398, Cluh

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003663731 – 1315Clustered mitochondria protein homologAdd BLAST1315

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei279PhosphoserineBy similarity1
Modified residuei281PhosphoserineBy similarity1
Modified residuei655PhosphoserineBy similarity1
Modified residuei725PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5SW19

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5SW19

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5SW19

PeptideAtlas

More...PeptideAtlasi		Q5SW19

PRoteomics IDEntifications database

More...PRIDEi		Q5SW19

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5SW19

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5SW19

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q5SW19

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		216526, 5 interactors

Protein interaction database and analysis system

More...IntActi		Q5SW19, 5 interactors

Molecular INTeraction database

More...MINTi		Q5SW19

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000090593

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5SW19, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini335 – 577CluPROSITE-ProRule annotationAdd BLAST243
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati980 – 1013TPR 1Add BLAST34
Repeati1022 – 1055TPR 2Add BLAST34
Repeati1106 – 1139TPR 3Add BLAST34
Repeati1148 – 1181TPR 4Add BLAST34

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CLU family.UniRule annotation

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1839, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5SW19

KEGG Orthology (KO)

More...KOi		K03255

Database of Orthologous Groups

More...OrthoDBi		60958at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5SW19

TreeFam database of animal gene trees

More...TreeFami		TF300565

Family and domain databases

Conserved Domains Database

More...CDDi		cd15466, CLU-central, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_03013, CLU, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR027523, CLU
IPR033646, CLU-central
IPR025697, CLU_dom
IPR028275, CLU_N
IPR011990, TPR-like_helical_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13236, CLU, 1 hit
PF15044, CLU_N, 1 hit
PF12807, eIF3_p135, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48452, SSF48452, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51823, CLU, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5SW19-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLNGDCSEN LKKEEGTSEP PRENGLDEGE PGDETTGQEV IVIQDTGFSV 
        60         70         80         90        100
KILAPGIEPF SLQVSPQEMV QEIHQVLMDR EDTCHRTCFS LHLDGNMLDH 
       110        120        130        140        150
FSELRSVEGL QEGSVLRVVE EPYTVREARI HVRHVRDLLK SLDPSDAFNG 
       160        170        180        190        200
VDCNSLSFLS VFTDGDLGDS GKRKKGLEMD PIDCTPPEYI LPGSRERPLC 
       210        220        230        240        250
PLQPQNRDWK PLQCLKVLTM SGWNPPPGNR KMHGDLMYLF VITAEDRQVS 
       260        270        280        290        300
ITASTRGFYL NQSTAYHFNP KPASPRFLSH SLVELLNQIS PTFKKNFAVL 
       310        320        330        340        350
QKKRVQRHPF ERIATPFQVY SWTAPQAEHA MDCVRAEDAY TSRLGYEEHI 
       360        370        380        390        400
PGQTRDWNEE LQTTRELPRK NLPERLLRER AIFKVHSDFT AAATRGAMAV 
       410        420        430        440        450
IDGNVMAINP SEETKMQMFI WNNIFFSLGF DVRDHYKDFG GDVAAYVAPT 
       460        470        480        490        500
NDLNGVRTYN AVDVEGLYTL GTVVVDYRGY RVTAQSIIPG ILERDQEQSV 
       510        520        530        540        550
IYGSIDFGKT VVSHPRYLEL LERTSRPLKI LRHRVLNDRD EEVELCSSVE 
       560        570        580        590        600
CKGIIGNDGR HYILDLLRTF PPDLNFLPVP GEELPEECSR AGFPRTHRHK 
       610        620        630        640        650
LCCLRQELVD AFVEHRYLLF MKLAALQLMQ QKASKVETTT SLENGGLPSS 
       660        670        680        690        700
AETKSEDSIG PEAGCEEEGS SVSGLAKVKE LAETIASDDG TVDPRSREVI 
       710        720        730        740        750
RNACKAVGSI SSTAFDIRFN PDIFSPGVRF PESCQDEVRD QKQLLKDAAA 
       760        770        780        790        800
FLLSCQIPGL VKDCTEYAVL PMDGATLAEV MRQRGINMRY LGKVLDLVLR 
       810        820        830        840        850
SPARDQLDHI YKIGIGELIT RSAKHIFKTY LQGVELSGLS AAISHFLNCF 
       860        870        880        890        900
LSSYPNPVAH LPADELLSKK RNKRRKNRPP GAADNTAWAV MTPQELWKNI 
       910        920        930        940        950
CHEAKNYFDF TLECDSVDQA VETYGLQKIT LLREISLKTG IQILLKEYSF 
       960        970        980        990       1000
DSRHKPAFTE EDVLNIFPVV KHVNPKASDA FHFFQSGQAK VQQGFLKEGC 
      1010       1020       1030       1040       1050
ELINEALNLF NNVYGAMHVE ICACLRLLAR LHYIMGDYAE ALSNQQKAVL 
      1060       1070       1080       1090       1100
MSERVMGIEH PNTIQEYMHL ALYCFASSQL STALSLLYRA RYLMLLVFGE 
      1110       1120       1130       1140       1150
DHPEMALLDN NIGLVLHGVM EYDLSLRFLE NALAVTTKYH GPKALKVALS 
      1160       1170       1180       1190       1200
HHLVARVYES KAEFRSALQH EKEGYTIYKT QLGEDHEKTK ESSEYLKCLT 
      1210       1220       1230       1240       1250
QQAVALQRTM NEIYRNGSSA NIPPLKFTAP SMTSVLEQLN VINGILFIPL 
      1260       1270       1280       1290       1300
SQKDLENLKA EVARRHQLQE ANRNRDKAEE QPMAPEPEPE PERAVEDMGS 
      1310 
PQTAKEGPSS LNLQG
Length:1,315
Mass (Da):148,068
Last modified:March 24, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i868CC53BDA8E3A65
GO
Isoform 2 (identifier: Q5SW19-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     762-856: KDCTEYAVLP...LNCFLSSYPN → REGLKGWVGA...CPISQRRRQI
     857-1315: Missing.

Show »
Length:818
Mass (Da):91,836
Checksum:iC4383C8232BD39B4
GO
Isoform 3 (identifier: Q5SW19-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     761-811: Missing.

Show »
Length:1,264
Mass (Da):142,251
Checksum:i5D3DD2D36406218C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4J140A0A0R4J140_MOUSE
Clustered mitochondria protein homo...
Cluh
1,353Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Z4YLI8Z4YLI8_MOUSE
Clustered mitochondria protein homo...
Cluh
1,302Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH72573 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE20503 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE32406 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE32929 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE34042 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAI24374 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAP19360 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti412E → D in AAH72573 (PubMed:15489334).Curated1
Sequence conflicti817E → D in BAE32406 (PubMed:16141072).Curated1
Sequence conflicti1284A → APE in BAE34042 (PubMed:16141072).Curated1
Sequence conflicti1284A → APE in BAC41440 (PubMed:12465718).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_036578761 – 811Missing in isoform 3. CuratedAdd BLAST51
Alternative sequenceiVSP_036579762 – 856KDCTE…SSYPN → REGLKGWVGAAERGCCPLVP PVPWFLDHIENLLVTSALAS PSLAHWQCPISQRRRQI in isoform 2. 1 PublicationAdd BLAST95
Alternative sequenceiVSP_036580857 – 1315Missing in isoform 2. 1 PublicationAdd BLAST459

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK036540 mRNA Translation: BAE20503.1 Different initiation.
AK154146 mRNA Translation: BAE32406.1 Different initiation.
AK154925 mRNA Translation: BAE32929.1 Different initiation.
AK157310 mRNA Translation: BAE34042.1 Different initiation.
AL607024 Genomic DNA Translation: CAI24374.1 Sequence problems.
AL607024 Genomic DNA Translation: CAP19360.1 Sequence problems.
BC060069 mRNA Translation: AAH60069.1
BC072573 mRNA Translation: AAH72573.1 Different initiation.
BC094446 mRNA Translation: AAH94446.1
AB093256 Transcribed RNA Translation: BAC41440.3

NCBI Reference Sequences

More...RefSeqi		NP_001074627.1, NM_001081158.2
XP_006534416.1, XM_006534353.3 [Q5SW19-1]
XP_006534417.1, XM_006534354.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		74148

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:74148

UCSC genome browser

More...UCSCi		uc007kca.1, mouse [Q5SW19-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036540 mRNA Translation: BAE20503.1 Different initiation.
AK154146 mRNA Translation: BAE32406.1 Different initiation.
AK154925 mRNA Translation: BAE32929.1 Different initiation.
AK157310 mRNA Translation: BAE34042.1 Different initiation.
AL607024 Genomic DNA Translation: CAI24374.1 Sequence problems.
AL607024 Genomic DNA Translation: CAP19360.1 Sequence problems.
BC060069 mRNA Translation: AAH60069.1
BC072573 mRNA Translation: AAH72573.1 Different initiation.
BC094446 mRNA Translation: AAH94446.1
AB093256 Transcribed RNA Translation: BAC41440.3
RefSeqiNP_001074627.1, NM_001081158.2
XP_006534416.1, XM_006534353.3 [Q5SW19-1]
XP_006534417.1, XM_006534354.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi216526, 5 interactors
IntActiQ5SW19, 5 interactors
MINTiQ5SW19
STRINGi10090.ENSMUSP00000090593

PTM databases

iPTMnetiQ5SW19
PhosphoSitePlusiQ5SW19
SwissPalmiQ5SW19

Proteomic databases

EPDiQ5SW19
jPOSTiQ5SW19
PaxDbiQ5SW19
PeptideAtlasiQ5SW19
PRIDEiQ5SW19

Genome annotation databases

GeneIDi74148
KEGGimmu:74148
UCSCiuc007kca.1, mouse [Q5SW19-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23277
MGIiMGI:1921398, Cluh

Rodent Unidentified Gene-Encoded large proteins database

More...Rougei		Search...

Phylogenomic databases

eggNOGiKOG1839, Eukaryota
InParanoidiQ5SW19
KOiK03255
OrthoDBi60958at2759
PhylomeDBiQ5SW19
TreeFamiTF300565

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		74148, 6 hits in 20 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Cluh, mouse

Protein Ontology

More...PROi		PR:Q5SW19
RNActiQ5SW19, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Family and domain databases

CDDicd15466, CLU-central, 1 hit
Gene3Di1.25.40.10, 1 hit
HAMAPiMF_03013, CLU, 1 hit
InterProiView protein in InterPro
IPR027523, CLU
IPR033646, CLU-central
IPR025697, CLU_dom
IPR028275, CLU_N
IPR011990, TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF13236, CLU, 1 hit
PF15044, CLU_N, 1 hit
PF12807, eIF3_p135, 1 hit
SUPFAMiSSF48452, SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS51823, CLU, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCLU_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SW19
Secondary accession number(s): A8Y5E2
, Q3U014, Q3U4M5, Q3V3Q8, Q505Q6, Q6GQX1, Q6PAT1, Q8CHD9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 24, 2009
Last modified: August 12, 2020
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again