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Protein
Submitted name:

Inducible T-cell costimulator

Gene

Icos

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Inducible T-cell costimulatorImported
Gene namesi
Name:IcosImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1858745 Icos

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei142 – 165HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500426229721 – 223Sequence analysisAdd BLAST203

Proteomic databases

PRIDEiQ5SUZ8

Expressioni

Gene expression databases

BgeeiENSMUSG00000026009
ExpressionAtlasiQ5SUZ8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5SUZ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 135IGvInterPro annotationAdd BLAST113

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J005 Eukaryota
ENOG41117EH LUCA
GeneTreeiENSGT00390000000801
HOVERGENiHBG052079
OMAiYNLDSSH
OrthoDBiEOG091G0IRJ
PhylomeDBiQ5SUZ8

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF15910 V-set_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SUZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPYFCRVFV FCFLIRLLTG EINGSADHRM FSFHNGGVQI SCKYPETVQQ
60 70 80 90 100
LKMRLFRERE VLCELTKTKG SGNAVSIKNP MLCLYHLSNN SVSFFLNNPD
110 120 130 140 150
SSQGSYYFCS LSIFDPPPFQ ERNLSGGYLH IYESQLCCQL KLWLPVGCAA
160 170 180 190 200
FVVVLLFGCI LIIWFSKKKY GSSVHDPNSE YMFMAAVNTN KKSRLAGTAP
210 220
LTALGREEHT SWLRLELICL FLF
Length:223
Mass (Da):25,435
Last modified:December 21, 2004 - v1
Checksum:iB2F6B0B8ACFAD78C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645744 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000027162; ENSMUSP00000027162; ENSMUSG00000026009

Similar proteinsi

Entry informationi

Entry nameiQ5SUZ8_MOUSE
AccessioniPrimary (citable) accession number: Q5SUZ8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: July 18, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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