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Entry version 103 (18 Sep 2019)
Sequence version 2 (15 May 2007)
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Protein

CST complex subunit CTC1

Gene

Ctc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation (PubMed:19854130). However, the CST complex has been shown to be involved in several aspects of telomere replication. The CST complex inhibits telomerase and is involved in telomere length homeostasis; it is proposed to bind to newly telomerase-synthesized 3' overhangs and to terminate telomerase action implicating the association with the ACD:POT1 complex thus interfering with its telomerase stimulation activity. The CST complex is also proposed to be involved in fill-in synthesis of the telomeric C-strand probably implicating recruitment and activation of DNA polymerase alpha. The CST complex facilitates recovery from many forms of exogenous DNA damage; seems to be involved in the re-initiation of DNA replication at repaired forks and/or dormant origins. Involved in telomere maintenance. Involved in genome stability (By similarity). May be in involved in telomeric C-strand fill-in during late S/G2 phase (PubMed:22748632).By similarity2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CST complex subunit CTC1
Alternative name(s):
Alpha-accessory factor of 132 kDa
Short name:
AAF-132
Short name:
AAF132
Conserved telomere maintenance component 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ctc1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1916214 Ctc1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus, Telomere

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002871831 – 1212CST complex subunit CTC1Add BLAST1212

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5SUQ9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5SUQ9

PeptideAtlas

More...
PeptideAtlasi
Q5SUQ9

PRoteomics IDEntifications database

More...
PRIDEi
Q5SUQ9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5SUQ9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5SUQ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000020898 Expressed in 278 organ(s), highest expression level in embryonic stem cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5SUQ9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5SUQ9 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the CST complex, composed of TEN1/C17orf106, CTC1/C17orf68 and STN1; in the complex interacts directly with STN1.

Interacts with ACD and POT1 (By similarity).

By similarity2 Publications

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-2130 CST complex

Protein interaction database and analysis system

More...
IntActi
Q5SUQ9, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000112063

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5SUQ9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CTC1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGVR Eukaryota
ENOG410Y8V3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011553

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5SUQ9

KEGG Orthology (KO)

More...
KOi
K23311

Identification of Orthologs from Complete Genome Data

More...
OMAi
FLWTLCT

Database of Orthologous Groups

More...
OrthoDBi
163417at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5SUQ9

TreeFam database of animal gene trees

More...
TreeFami
TF335866

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029156 CTC1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15489 CTC1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5SUQ9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAACRAQPPT SEQAWLEAAQ TFIQETLCPA GKEVDKELTR SVIACVKETW
60 70 80 90 100
LSQGENQDLT LPFSYSFVSV QSLKTHQRLP CCSHLSWSQS AYQAWTRGGR
110 120 130 140 150
PGDGVLPREQ LILLGTLVDL LGDSEQECRS GSLYVRDNTG TLDCELIDLD
160 170 180 190 200
LSWLGHLFLF PSWSYLPSAK RNSLGEGHLE LWGTPVPVFP LTVSPGPLIP
210 220 230 240 250
IPVLYPEKAS HLLRYRKKSS IKEINLAGKL VHLSALIITQ NKRYFIMTLG
260 270 280 290 300
ELAQAGSQVS IIVQIPAQMV WHRVLRPGRA YVLTKLQVTK TRIHLSCIWT
310 320 330 340 350
TIPSSTLKPL RPGYVQELEL DLEFSKADLK PPPQPTSSKD SRGQEGLVRA
360 370 380 390 400
SKVLHYLGTV TAVLHESAGL YILDGQLILC LAYQKIHGLR RVIRPGVCLE
410 420 430 440 450
LRDVHLLQAV GGATTKPVLA LCLHGTVRLQ GFSCLKPLTL PSSKVYGASL
460 470 480 490 500
YEQLVWKCQL GLPLYLWAAK TLEDLIYKLC PHVLRCHQFL KQPSPGKPSL
510 520 530 540 550
GLQLLAPSWD VLIPPGSPMR HAYSEILEEP HNCPLQKYTP LQTPYSFPTM
560 570 580 590 600
LALAEEGQHR AWATFDPKAM LPLPEASHLT SCQLNRHLAW SWVCLPSCVF
610 620 630 640 650
QPAQVLLGVL VASSRKGCLE LRDLRGSLPC IPLTESSQPL IDPNLVGCLV
660 670 680 690 700
RVEKFQLVVE REVRSSFPSW EEMGMARFIQ KKQARVYVQF YLADALILPV
710 720 730 740 750
PRPTFGSEPS QTASSCPEGP HLGQSRLFLL SHKEALMKRN FCLLPGDSSQ
760 770 780 790 800
PAKPTLSFHV SGTWLCGTQR KEGSGWSPPE SLAVESKDQK VFLIFLGSSV
810 820 830 840 850
RWFPFLYPNQ VYRLVASGPS QTPVFETEGS AGTSRRPLEL ADCGSCLTVQ
860 870 880 890 900
EEWTLELGSS QDIPNVLEVP RTLPESSLAQ LLGDNSPDSL VSFSAEILSR
910 920 930 940 950
ILCEPPLALR RMKPGNAGAI KTGVKLTVAL EMDDCEYPPH LDIYIEDPQL
960 970 980 990 1000
PPQIGLLPGA RVHFSQLEKR ISRSNIVYCC FRSSTSVQVL SFPPETKASA
1010 1020 1030 1040 1050
PLPHIYLAEL LQGDRPPFQA TTSCHIVYVL SLQILWVCAH CTSICPQGKC
1060 1070 1080 1090 1100
SRRDPSCPSQ RAVSQANIRL LVEDGTAEAT VICRNHLVAR ALGLSPSEWS
1110 1120 1130 1140 1150
SILEHARGPG RVALQFTGLG GQTESASKTH EPLTLLLRTL CTSPFVLRPV
1160 1170 1180 1190 1200
KLSFALERRP TDISPREPSR LQQFQCGELP LLTRVNPRLR LVCLSLQEPE
1210
LPNPPQASAA SS
Length:1,212
Mass (Da):134,028
Last modified:May 15, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4254E5B091CA5E1D
GO
Isoform 2 (identifier: Q5SUQ9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     821-821: Missing.

Note: No experimental confirmation available.
Show »
Length:1,211
Mass (Da):133,900
Checksum:iD69B4C4B68318C6C
GO
Isoform 3 (identifier: Q5SUQ9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-246: Missing.

Note: No experimental confirmation available.
Show »
Length:966
Mass (Da):106,599
Checksum:i5DC356B9D334A1E9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E0CXE7E0CXE7_MOUSE
CST complex subunit CTC1
Ctc1 1500010J02Rik
965Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CXT1E0CXT1_MOUSE
CST complex subunit CTC1
Ctc1 1500010J02Rik
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH14687 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAH60629 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC30081 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAE26750 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAE38452 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti446Missing in BAC30081 (PubMed:16141072).Curated1
Sequence conflicti969K → E in BAE26750 (PubMed:16141072).Curated1
Sequence conflicti1144P → H in BAE26750 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0253541 – 246Missing in isoform 3. 1 PublicationAdd BLAST246
Alternative sequenceiVSP_025355821Missing in isoform 2. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK005190 mRNA Translation: BAB23872.1
AK038651 mRNA Translation: BAC30081.1 Different initiation.
AK044055 mRNA Translation: BAC31756.1
AK145919 mRNA Translation: BAE26750.1 Different initiation.
AK165906 mRNA Translation: BAE38452.1 Different initiation.
AL645902 Genomic DNA No translation available.
BC014687 mRNA Translation: AAH14687.1 Different initiation.
BC060629 mRNA Translation: AAH60629.3 Different initiation.
BC147495 mRNA Translation: AAI47496.1
BC147497 mRNA Translation: AAI47498.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS36189.2 [Q5SUQ9-1]
CCDS48824.1 [Q5SUQ9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001013274.2, NM_001013256.2 [Q5SUQ9-1]
NP_001137262.1, NM_001143790.1 [Q5SUQ9-2]
NP_001268394.1, NM_001281465.1 [Q5SUQ9-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000021278; ENSMUSP00000021278; ENSMUSG00000020898 [Q5SUQ9-2]
ENSMUST00000116359; ENSMUSP00000112063; ENSMUSG00000020898 [Q5SUQ9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
68964

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:68964

UCSC genome browser

More...
UCSCi
uc007jox.2 mouse [Q5SUQ9-1]
uc007joz.2 mouse [Q5SUQ9-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005190 mRNA Translation: BAB23872.1
AK038651 mRNA Translation: BAC30081.1 Different initiation.
AK044055 mRNA Translation: BAC31756.1
AK145919 mRNA Translation: BAE26750.1 Different initiation.
AK165906 mRNA Translation: BAE38452.1 Different initiation.
AL645902 Genomic DNA No translation available.
BC014687 mRNA Translation: AAH14687.1 Different initiation.
BC060629 mRNA Translation: AAH60629.3 Different initiation.
BC147495 mRNA Translation: AAI47496.1
BC147497 mRNA Translation: AAI47498.1
CCDSiCCDS36189.2 [Q5SUQ9-1]
CCDS48824.1 [Q5SUQ9-2]
RefSeqiNP_001013274.2, NM_001013256.2 [Q5SUQ9-1]
NP_001137262.1, NM_001143790.1 [Q5SUQ9-2]
NP_001268394.1, NM_001281465.1 [Q5SUQ9-3]

3D structure databases

SMRiQ5SUQ9
ModBaseiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-2130 CST complex
IntActiQ5SUQ9, 3 interactors
STRINGi10090.ENSMUSP00000112063

PTM databases

iPTMnetiQ5SUQ9
PhosphoSitePlusiQ5SUQ9

Proteomic databases

EPDiQ5SUQ9
PaxDbiQ5SUQ9
PeptideAtlasiQ5SUQ9
PRIDEiQ5SUQ9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021278; ENSMUSP00000021278; ENSMUSG00000020898 [Q5SUQ9-2]
ENSMUST00000116359; ENSMUSP00000112063; ENSMUSG00000020898 [Q5SUQ9-1]
GeneIDi68964
KEGGimmu:68964
UCSCiuc007jox.2 mouse [Q5SUQ9-1]
uc007joz.2 mouse [Q5SUQ9-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80169
MGIiMGI:1916214 Ctc1

Phylogenomic databases

eggNOGiENOG410IGVR Eukaryota
ENOG410Y8V3 LUCA
GeneTreeiENSGT00390000011553
InParanoidiQ5SUQ9
KOiK23311
OMAiFLWTLCT
OrthoDBi163417at2759
PhylomeDBiQ5SUQ9
TreeFamiTF335866

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ctc1 mouse

Protein Ontology

More...
PROi
PR:Q5SUQ9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000020898 Expressed in 278 organ(s), highest expression level in embryonic stem cell
ExpressionAtlasiQ5SUQ9 baseline and differential
GenevisibleiQ5SUQ9 MM

Family and domain databases

InterProiView protein in InterPro
IPR029156 CTC1
PfamiView protein in Pfam
PF15489 CTC1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTC1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SUQ9
Secondary accession number(s): B2RW14
, Q3UKQ1, Q6P9S2, Q8BRK2, Q91WN0, Q9CW32
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: September 18, 2019
This is version 103 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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