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Protein
Submitted name:

Sodium-dependent lysophosphatidylcholine symporter 1

Gene

MFSD2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium-dependent lysophosphatidylcholine symporter 1Imported
Gene namesi
Name:MFSD2AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000168389.17
HGNCiHGNC:25897 MFSD2A

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei113 – 134HelicalSequence analysisAdd BLAST22
Transmembranei146 – 170HelicalSequence analysisAdd BLAST25
Transmembranei239 – 262HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168389

PTM / Processingi

Proteomic databases

EPDiQ5SSK0
PeptideAtlasiQ5SSK0

Expressioni

Gene expression databases

BgeeiENSG00000168389 Expressed in 171 organ(s), highest expression level in placenta
ExpressionAtlasiQ5SSK0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5SSK0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000005318
HOGENOMiHOG000294186
HOVERGENiHBG080097

Family and domain databases

InterProiView protein in InterPro
IPR036259 MFS_trans_sf
SUPFAMiSSF103473 SSF103473, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q5SSK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKGEGAESG SAAGLLPTSI LQSTERPAQK EPKKKKQQLS VCNKLCYALG
60 70 80 90 100
GAPYQVTGCA LGFFLQIYLL DVAQVGPFSA SIILFVGRAW DAITDPLVGL
110 120 130 140 150
CISKSPWTCL GRLMPWIIFS TPLAVIAYFL IWFVPDFPHG QTYWYLLFYC
160 170 180 190 200
LFETMVTCFH VPYSALTMFI STEQTERDSA TAYRMTVEVL GTVLGTAIQG
210 220 230 240 250
QIVGQADTPC FQDLNSSTVA SQSANHTHGT TSHRETQKAY LLAAGVIVCI
260
YIICAVILIL GVREQR
Length:266
Mass (Da):29,097
Last modified:December 21, 2004 - v1
Checksum:iBB8E3D8FC541CA1E
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8NA29NLS1_HUMAN
Sodium-dependent lysophosphatidylch...
MFSD2A MFSD2, NLS1, HMFN0656, PP9177, UNQ300/PRO341
543Annotation score:
E7EPI8E7EPI8_HUMAN
Sodium-dependent lysophosphatidylch...
MFSD2A
374Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei266Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663070 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000434861; ENSP00000407606; ENSG00000168389
UCSCiuc057fdl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663070 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5SSK0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiQ5SSK0
PeptideAtlasiQ5SSK0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000434861; ENSP00000407606; ENSG00000168389
UCSCiuc057fdl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168389.17
HGNCiHGNC:25897 MFSD2A
OpenTargetsiENSG00000168389
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000005318
HOGENOMiHOG000294186
HOVERGENiHBG080097

Miscellaneous databases

ChiTaRSiMFSD2A human

Gene expression databases

BgeeiENSG00000168389 Expressed in 171 organ(s), highest expression level in placenta
ExpressionAtlasiQ5SSK0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR036259 MFS_trans_sf
SUPFAMiSSF103473 SSF103473, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SSK0_HUMAN
AccessioniPrimary (citable) accession number: Q5SSK0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 12, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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