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UniProtKB - Q5SSK0 (Q5SSK0_HUMAN)
Protein
Submitted name:
Sodium-dependent lysophosphatidylcholine symporter 1
Gene
MFSD2A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- symporter activity Source: InterPro
GO - Biological processi
- carbohydrate transport Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Sodium-dependent lysophosphatidylcholine symporter 1 |
Gene namesi | Name:MFSD2A |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25897, MFSD2A |
VEuPathDBi | HostDB:ENSG00000168389 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 113 – 134 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 146 – 170 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 239 – 262 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000168389, Expressed in placenta and 190 other tissues |
ExpressionAtlasi | Q5SSK0, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 33 | DisorderedSequence analysisAdd BLAST | 33 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00390000005318 |
HOGENOMi | CLU_027408_6_2_1 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR039672, MFS_2 IPR036259, MFS_trans_sf |
PANTHERi | PTHR11328, PTHR11328, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q5SSK0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKGEGAESG SAAGLLPTSI LQSTERPAQK EPKKKKQQLS VCNKLCYALG
60 70 80 90 100
GAPYQVTGCA LGFFLQIYLL DVAQVGPFSA SIILFVGRAW DAITDPLVGL
110 120 130 140 150
CISKSPWTCL GRLMPWIIFS TPLAVIAYFL IWFVPDFPHG QTYWYLLFYC
160 170 180 190 200
LFETMVTCFH VPYSALTMFI STEQTERDSA TAYRMTVEVL GTVLGTAIQG
210 220 230 240 250
QIVGQADTPC FQDLNSSTVA SQSANHTHGT TSHRETQKAY LLAAGVIVCI
260
YIICAVILIL GVREQR
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8NA29 | NLS1_HUMAN | Sodium-dependent lysophosphatidylch... | MFSD2A MFSD2, NLS1, HMFN0656, PP9177, UNQ300/PRO341 | 543 | Annotation score: | ||
E7EPI8 | E7EPI8_HUMAN | Sodium-dependent lysophosphatidylch... | MFSD2A | 374 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 266 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL663070 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000434861.5; ENSP00000407606.1; ENSG00000168389.18 |
UCSCi | uc057fdl.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL663070 Genomic DNA No translation available. |
3D structure databases
SMRi | Q5SSK0 |
ModBasei | Search... |
Proteomic databases
EPDi | Q5SSK0 |
PeptideAtlasi | Q5SSK0 |
PRIDEi | Q5SSK0 |
Protocols and materials databases
Antibodypediai | 31983, 103 antibodies from 21 providers |
Genome annotation databases
Ensembli | ENST00000434861.5; ENSP00000407606.1; ENSG00000168389.18 |
UCSCi | uc057fdl.1, human |
Organism-specific databases
HGNCi | HGNC:25897, MFSD2A |
OpenTargetsi | ENSG00000168389 |
VEuPathDBi | HostDB:ENSG00000168389 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000005318 |
HOGENOMi | CLU_027408_6_2_1 |
Miscellaneous databases
ChiTaRSi | MFSD2A, human |
Gene expression databases
Bgeei | ENSG00000168389, Expressed in placenta and 190 other tissues |
ExpressionAtlasi | Q5SSK0, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR039672, MFS_2 IPR036259, MFS_trans_sf |
PANTHERi | PTHR11328, PTHR11328, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5SSK0_HUMAN | |
Accessioni | Q5SSK0Primary (citable) accession number: Q5SSK0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 21, 2004 |
Last sequence update: | December 21, 2004 | |
Last modified: | May 25, 2022 | |
This is version 101 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |